There are 6 ways to get from Indianapolis to Independence by bus, train, bus (Greyhound), car, plane, or train (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train
best- Take the bus from Indianapolis Union Station to St Louis Bus StationGreyhound US0421
- Take the train from St. Louis to Independence StationMissouri River Runner / ...
10h 5m$68–180Bus (Greyhound)
- Take the bus from Indianapolis Union Station to St Louis Bus StationGreyhound US0421
- Take the bus from St Louis Bus Station to Kansas City Bus StationGreyhound US1200 / ...
11h 8m$73–195Drive 473.9 mi
- Drive from Indianapolis to Independence473.9 mi
7h 56m$87–125Fly from Indianapolis, line 24 bus
- Fly from Indianapolis (IND) to Kansas City (MCI)IND - MCI
- Take the bus from East Village - Bay A to On White Oak At Osage Eb
6h 35m$182–472Train (Amtrak)
- Take the train from Indianapolis to Chicago Union StationCardinal
- Take the train from Chicago Union Station to Independence StationLincoln Service Missouri River Runner
16h 21m$101–447Train to Purdue University Airport, fly
- Take the train from Indianapolis to Lafayette Amtrak Station
- Fly from Purdue University Airport (LAF) to Kansas City (MCI)LAF - MCI
10h 35m$112–542
Indianapolis to Independence by bus and train
Questions & Answers
The cheapest way to get from Indianapolis to Independence is to bus and train which costs $65 - $180 and takes 10h 5m.
The fastest way to get from Indianapolis to Independence is to fly and line 24 bus which takes 6h 35m and costs $180 - $480.
No, there is no direct bus from Indianapolis station to Independence. However, there are services departing from Indianapolis Union Station and arriving at On White Oak At Osage Eb via St Louis Bus Station and East Village - Bay A. The journey, including transfers, takes approximately 11h 8m.
No, there is no direct train from Indianapolis to Independence station. However, there are services departing from Indianapolis and arriving at Independence Station via Chicago Union Station. The journey, including transfers, takes approximately 16h 21m.
The distance between Indianapolis and Independence is 514 miles. The road distance is 476.7 miles.
The best way to get from Indianapolis to Independence without a car is to bus and train which takes 10h 5m and costs $65 - $180.
It takes approximately 10h 5m to get from Indianapolis to Independence, including transfers.
Indianapolis to Independence bus services, operated by Greyhound USA, depart from Indianapolis Union Station.
Indianapolis to Independence train services, operated by Amtrak, depart from Indianapolis station.
The best way to get from Indianapolis to Independence is to bus which takes 11h 8m and costs $70 - $200. Alternatively, you can train, which costs $100 - $450 and takes 16h 21m.
What companies run services between Indianapolis, IN, USA and Independence, MO, USA?
You can take a bus from Indianapolis Union Station to On White Oak At Osage Eb via St Louis Bus Station, Kansas City Bus Station, and East Village - Bay A in around 11h 8m. Alternatively, you can take a train from Indianapolis to Independence Station via Chicago Union Station in around 16h 21m.
- Website
- southwest.com
Flights from Indianapolis to Kansas City
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $95–600
Flights from Indianapolis to Kansas City via Chicago Midway
- Ave. Duration
- 4h
- When
- Monday, Tuesday, Friday, Saturday, and Sunday
- Estimated price
- $110–600
- Website
- united.com
Flights from Purdue University Airport to Kansas City via Chicago O'Hare
- Ave. Duration
- 4h 43m
- When
- Every day
- Estimated price
- $85–490
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from St. Louis to Independence Station
- Ave. Duration
- 5h 10m
- Frequency
- Twice daily
- Estimated price
- $30–65
- Website
- https://www.amtrak.com/home.html
Train from Indianapolis to Chicago Union Station
- Ave. Duration
- 5h
- Frequency
- 3 times a week
- Estimated price
- $35–300
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Independence Station
- Ave. Duration
- 10h 21m
- Frequency
- Once daily
- Estimated price
- $65–150
- Website
- https://www.amtrak.com/home.html
Train from Indianapolis to Lafayette Amtrak Station
- Ave. Duration
- 1h 35m
- Frequency
- 3 times a week
- Estimated price
- $25–55
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Indianapolis Union Station to St Louis Bus Station
- Ave. Duration
- 3h 55m
- Frequency
- 3 times a day
- Estimated price
- $35–120
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Kansas City Bus Station
- Ave. Duration
- 4h 30m
- Frequency
- 4 times a day
- Estimated price
- $35–80
- Website
- https://www.greyhound.com/
- Phone
- +1 816-221-0660
- Website
- ridekc.org
Bus from East Village - Bay A to On White Oak At Osage Eb
- Ave. Duration
- 41 min
- Frequency
- Hourly
- Schedules at
- ridekc.org
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More Questions & Answers
Indianapolis to Independence bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Independence is 1h behind Indianapolis. It is currently 5:09 PM in Indianapolis and 4:09 PM in Independence.
Indianapolis to Independence train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Indianapolis to Independence is 477 miles. It takes approximately 7h 56m to drive from Indianapolis to Independence.
Book your Indianapolis to Independence train tickets online with Omio.
There are 236+ hotels available in Independence.






