There are 4 ways to get from Indianapolis to Great Smoky Mountains National Park by plane, car or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Knoxville, drive  •  6 h 33 min

  1. Fly from Indianapolis (IND) to Knoxville (TYS) IND - TYS
  2. Drive from Knoxville to Great Smoky Mountains National Park

$207 - $1,111

Cheapest option

Bus, Megabus, drive  •  13 h 6 min

  1. Take the bus from Indianapolis, IN to Chattanooga
  2. Take the Megabus from Chattanooga to Knoxville
  3. Drive from Knoxville to Great Smoky Mountains National Park

$58 - $83

2 alternative options

Fly to Asheville, drive  •  6 h 58 min

  1. Fly from Indianapolis (IND) to Asheville (AVL) IND - AVL
  2. Drive from Asheville to Great Smoky Mountains National Park

$239 - $1,114

Drive  •  6 h 51 min

  1. Drive from Indianapolis to Great Smoky Mountains National Park 421.2 miles

$40 - $60

Questions & Answers

The cheapest way to get from Indianapolis to Great Smoky Mountains National Park is to drive which costs $40 - $60 and takes 6 h 51 min.

More details

The quickest way to get from Indianapolis to Great Smoky Mountains National Park is to fly and drive which costs $200 - $1,200 and takes 6 h 33 min.

More details

The distance between Indianapolis and Great Smoky Mountains National Park is 324 miles. The road distance is 421.2 miles.

Get driving directions

It takes approximately 6 h 33 min to get from Indianapolis to Great Smoky Mountains National Park, including transfers.

More details

What companies run services between Indianapolis, IN, USA and Great Smoky Mountains National Park, TN, USA?

There is no direct connection from Indianapolis to Great Smoky Mountains National Park. However, you can take the line 8 bus to Indianapolis Airport, take the walk to Indianapolis airport, fly to Knoxville, then take the drive to Great Smoky Mountains National Park. Alternatively, you can take the line 8 bus to Indianapolis Airport, take the walk to Indianapolis airport, fly to Asheville, then take the drive to Great Smoky Mountains National Park.

Airlines
Delta
Website
delta.com
Flights from Indianapolis to Knoxville via Atlanta
Ave. Duration
3 h 47 min
When
Every day
Estimated price
$200 - $1,100
Flights from Indianapolis to Knoxville via Detroit
Ave. Duration
3 h 49 min
When
Every day
Estimated price
$210 - $1,100
Flights from Indianapolis to Asheville via Atlanta
Ave. Duration
3 h 58 min
When
Every day
Estimated price
$200 - $1,100
American Airlines
Website
aa.com
Flights from Indianapolis to Knoxville via Charlotte
Ave. Duration
3 h 54 min
When
Every day
Estimated price
$210 - $1,100
Flights from Indianapolis to Knoxville via Chicago O'Hare
Ave. Duration
4 h 17 min
When
Every day
Estimated price
$220 - $1,100
Flights from Indianapolis to Knoxville via Reagan Washington
Ave. Duration
4 h 9 min
When
Every day
Estimated price
$240 - $1,100
Flights from Indianapolis to Asheville via Charlotte
Ave. Duration
4 h 15 min
When
Every day
Estimated price
$210 - $1,100
United Airlines
Website
united.com
Flights from Indianapolis to Knoxville via Chicago O'Hare
Ave. Duration
3 h 44 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$230 - $1,100
Flights from Indianapolis to Knoxville via Washington Dulles
Ave. Duration
3 h 54 min
When
Every day
Estimated price
$250 - $1,200
Flights from Indianapolis to Asheville via Chicago O'Hare
Ave. Duration
5 h 23 min
When
Every day
Estimated price
$240 - $1,200
Flights from Indianapolis to Asheville via Newark
Ave. Duration
5 h 55 min
When
Saturday
Estimated price
$290 - $1,300
Allegiant Air
Website
allegiantair.com
Flights from Indianapolis to Asheville via St. Petersburg
Ave. Duration
5 h 54 min
When
Thursday and Sunday
Estimated price
$230 - $1,100
Bus operators
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from Indianapolis, IN to Chattanooga
Ave. Duration
8 h 31 min
Frequency
Twice daily
Estimated price
$40 - $55
Schedules at
us.megabus.com
Bus from Chattanooga to Knoxville
Ave. Duration
2 h
Frequency
Twice daily
Estimated price
$12 - $22
Schedules at
us.megabus.com

Want to know more about travelling around the world?

Rome2rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including How do I get from Sydney to Melbourne, Which side of Niagara Falls should I choose (and how do I get there)? and Want to know more about US trains? - to help you get the most out of your next trip.

Trips to Great Smoky Mountains National Park