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How to get fromIndianapolis to Durhamby plane, bus, bus (Flixbus, Greyhound), train (Amtrak), car, or train

Find Transport to Durham

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There are 8 ways to get from Indianapolis to Durham by plane, bus, bus (Flixbus, Greyhound), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Indianapolis to Raleigh-Durham International Airport, bus, line 700 bus

    best
    1. Fly from Indianapolis (IND) to Raleigh-Durham International Airport (RDU)plane plane IND - RDU
    2. Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus bus
    3. Take the bus from Regional Transit Center to Duke St at Jackson Stbus bus
    5h
    $168–378

  2. Drive  589.1 mi

    cheapest
    1. Drive from Indianapolis to Durhamcar car 589.1 mi
    10h 27m
    $108–156

  3. Bus

    1. Take the bus from Indianapolis to Columbusbus bus
    2. Take the bus from Columbus to Winston Salem(Trans Center)bus bus
    3. Take the bus from Winston Salem(Trans Center) to Durhambus bus
    16h 57m
    $114–175

  4. Train (Amtrak)

    1. Take the train from Indianapolis to Charlottesvilletrain train
    2. Take the train from Charlottesville to Greensborotrain train
    3. Take the train from Greensboro to Durham Amtrak Stationtrain train
    21h 54m
    $461–715

  5. Fly Indianapolis to Piedmont Triad International Airport, train

    1. Fly from Indianapolis (IND) to Piedmont Triad International Airport (GSO)plane plane IND - GSO
    2. Take the train from Greensboro to Durham Amtrak Stationtrain train
    7h 45m
    $211–1,037

  6. Bus to Covington, fly to Raleigh-Durham International Airport

    1. Take the bus from Indianapolis to Cincinnatibus bus
    2. Fly from Covington (CVG) to Raleigh-Durham International Airport (RDU)plane plane CVG - RDU
    7h 17m
    $120–686

  7. Train via Arlington (Amtrak)

    1. Take the train from Indianapolis to Alexandriatrain train Cardinal
    2. Take the train from Alexandria to Durham Amtrak Stationtrain train Carolinian
    25h 44m
    $563–884

  8. Bus, train

    1. Take the bus from Indianapolis to Toledobus bus Bsb 14
    2. Take the train from Toledo to Raleigh Union Stationtrain train Floridian
    26h 25m
    $485–813

Indianapolis to Durham by bus and foot

Calendar7Weekly Services
Duration16h 57mAverage Duration
Ticket$114Cheapest Price
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Comparing Your Travel Options

Map of how to get from Indianapolis to Durham.ExpandLaunch map view
  • Distance: 520.4 mi
  • Duration: 5h

What companies run services between Indianapolis, IN, USA and Durham, NC, USA?

You can take a bus from Indianapolis to Durham via Columbus, E Main St & S 5Th St, S Grant Ave & E Mound St, Columbus, and Winston Salem(Trans Center) in around 16h 57m. Alternatively, you can take a train from Indianapolis to Durham Amtrak Station via Charlottesville and Greensboro in around 21h 54m.

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