There are 5 ways to get from Indianapolis to Buffalo by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  5 h 43 min

  1. Fly from Indianapolis (IND) to Buffalo (BUF) IND - BUF

$164 - $449

Cheapest option

Bus  •  11 h 25 min

  1. Take the bus from Indianapolis, IN to Richmond, IN
  2. Take the bus from Richmond, IN to Columbus, OH
  3. Take the bus from Columbus, Oh to Cleveland, Oh
  4. Take the bus from Cleveland, Oh to Buffalo, Ny 212

$72 - $163

3 alternative options

Train  •  17 h 21 min

  1. Take the train from Indianapolis Amtrak to Chicago Union Station Amtrak Hoosier State / ...
  2. Take the train from Chicago Union Station Amtrak to Buffalo Depew Station Amtrak Lake Shore Limited

$135 - $368

Bus, Thru-Bus  •  18 h 49 min

  1. Take the bus from Indianapolis, IN to Ann Arbor, MI
  2. Take the bus from Ann Arbor, MI to Hamilton, ON
  3. Take the Thru-Bus from Hamilton, ON to Buffalo, NY

$82 - $189

Drive  •  8 h 27 min

  1. Drive from Indianapolis to Buffalo 502.7 miles

$45 - $75

Questions & Answers

The cheapest way to get from Indianapolis to Buffalo is to drive which costs $45 - $75 and takes 8 h 27 min.

More details

The quickest way to get from Indianapolis to Buffalo is to fly which costs $160 - $450 and takes 5 h 43 min.

More details

The distance between Indianapolis and Buffalo is 437 miles. The road distance is 502.7 miles.

Get driving directions

It takes approximately 5 h 43 min to get from Indianapolis to Buffalo, including transfers.

More details

No, there is no direct bus from Indianapolis to Buffalo. However, there are services departing from Indianapolis, IN and arriving at Buffalo, Ny via Richmond, IN, Columbus, Oh and Cleveland, Oh. The journey, including transfers, takes approximately 11 h 25 min.

More details

No, there is no direct train from Indianapolis to Buffalo. However, there are services departing from Indianapolis Amtrak and arriving at Buffalo via Chicago Union Station Amtrak and Buffalo. The journey, including transfers, takes approximately 17 h 21 min.

More details

The best way to get from Indianapolis to Buffalo without a car is to bus which takes 11 h 25 min and costs $70 - $170.

More details

Map of how to get from Indianapolis to Buffalo.
Launch map view
  • Distance: 437.1 miles
  • Duration: 5 h 43 min

What companies run services between Indianapolis, IN, USA and Buffalo, NY, USA?

Delta, Southwest Airlines and two other airlines fly from Indianapolis to Buffalo hourly. Alternatively, you can take a bus from Indianapolis to Buffalo via Richmond, IN, Columbus, OH, Columbus, Oh, and Cleveland, Oh in around 11 h 25 min.

Airlines
United Airlines
Website
united.com
Flights from Indianapolis to Buffalo via Washington Dulles
Ave. Duration
3 h 53 min
When
Every day
Estimated price
$170 - $750
Flights from Indianapolis to Buffalo via Chicago O'Hare
Ave. Duration
3 h 49 min
When
Every day
Estimated price
$170 - $750
Southwest Airlines
Website
southwest.com
Flights from Indianapolis to Buffalo via Chicago Midway
Ave. Duration
3 h 36 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$390 - $750
Flights from Indianapolis to Buffalo via Baltimore
Ave. Duration
4 h 10 min
When
Every day
Estimated price
$390 - $750
American Airlines
Website
aa.com
Flights from Indianapolis to Buffalo via Reagan Washington
Ave. Duration
3 h 53 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$170 - $850
Flights from Indianapolis to Buffalo via Chicago O'Hare
Ave. Duration
3 h 57 min
When
Every day
Estimated price
$170 - $850
Flights from Indianapolis to Buffalo via Philadelphia
Ave. Duration
4 h 1 min
When
Saturday
Estimated price
$170 - $850
Delta
Website
delta.com
Flights from Indianapolis to Buffalo via Detroit
Ave. Duration
3 h 29 min
When
Every day
Estimated price
$170 - $700
Train operators
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Indianapolis Amtrak to Chicago Union Station Amtrak
Ave. Duration
5 h
Frequency
Once daily
Estimated price
$40 - $100
Website
amtrak.com
Coach Seat
$40 - $60
Flexi Coach Seat
$70 - $110
Business Coach Seat
$70 - $100
Room
$200 - $280
Train from Chicago Union Station Amtrak to Buffalo Depew Station Amtrak
Ave. Duration
10 h 16 min
Frequency
Twice daily
Estimated price
$75 - $220
Website
amtrak.com
Coach Seat
$75 - $120
Flexi Coach Seat
$140 - $200
Business Coach Seat
$150 - $220
Room
$330 - $460
Bus operators
Barons Bus
Website
baronsbus.com
Bus from Indianapolis, IN to Richmond, IN
Ave. Duration
1 h 34 min
Frequency
Once daily
Estimated price
$13 - $25
Schedules at
baronsbus.com
Bus from Richmond, IN to Columbus, OH
Ave. Duration
2 h 10 min
Frequency
3 times a day
Estimated price
$15 - $28
Schedules at
baronsbus.com
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Columbus, Oh to Cleveland, Oh
Ave. Duration
2 h 20 min
Frequency
Hourly
Estimated price
$19 - $50
Website
greyhound.com
Economy
$19 - $30
Flexible
$35 - $50
Bus from Cleveland, Oh to Buffalo, Ny
Ave. Duration
3 h 45 min
Frequency
Every 30 minutes
Estimated price
$24 - $60
Website
greyhound.com
Economy
$24 - $40
Flexible
$45 - $60
Greyhound Canada
Phone
+1 1-800-661-8747
Email
Canada.info@greyhound.ca
Website
greyhound.ca
Bus from Ann Arbor, MI to Hamilton, ON
Ave. Duration
5 h 54 min
Frequency
Once daily
Estimated price
$25 - $65
Website
Greyhound.ca
Advanced Purchase
$25 - $40
Online Fare
$30 - $50
Standard Fare
$40 - $65
Refundable
$45 - $70
Bus from Hamilton, ON to Buffalo, NY
Ave. Duration
2 h 40 min
Frequency
Once daily
Estimated price
$12 - $35
Website
Greyhound.ca
Advanced Purchase
$12 - $18
Online Fare
$13 - $27
Standard Fare
$21 - $35
Refundable
$25 - $40

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