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How to get fromIndianapolis to BuffaloBy plane, bus, train, car, shuttle, bus (Flixbus, Greyhound), or train (Amtrak)

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There are 8 ways to get from Indianapolis to Buffalo by plane, bus, train, car, shuttle, bus (Flixbus, Greyhound), or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Buffalo Niagara International Airport

    best
    1. Fly from Indianapolis (IND) to Buffalo Niagara International Airport (BUF)plane plane IND - BUF
    6h 13m
    $147–930

  2. Bus

    cheapest
    1. Take the bus from Indianapolis, IN to Toledobus bus
    2. Take the bus from Toledo to Clevelandbus bus
    3. Take the bus from Cleveland, OH to Buffalo, NYbus bus
    10h 50m
    $51–165

  3. Bus, train

    1. Take the bus from Indianapolis, IN to Toledobus bus Cincinnati
    2. Take the train from Toledo to Buffalo Depew Stationtrain train Lake Shore Limited
    11h 38m
    $111–315

  4. Drive 494.8 mi

    1. Drive from Indianapolis to Buffalocar car 494.8 mi
    8h 38m
    $91–131

  5. Fly to Rochester, bus

    1. Fly from Indianapolis (IND) to Rochester (ROC)plane plane IND - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    7h 38m
    $129–647

  6. Fly to Toronto Pearson International Airport, shuttle

    1. Fly from Indianapolis (IND) to Toronto Pearson International Airport (YYZ)plane plane IND - YYZ
    2. Take a shuttle bus from Pearson International Airport Terminal 1 to Buffalo Airportshuttle bus
    7h 57m
    $357–1,000

  7. Bus via Dayton

    1. Take the bus from Indianapolis to Dayton Trotwood Bus Stationbus bus
    2. Take the bus from Dayton Trotwood Bus Station to Cleveland Bus Stationbus bus
    3. Take the bus from Cleveland Bus Station to Buffalobus bus
    12h 50m
    $79–163

  8. Train (Amtrak)

    1. Take the train from Indianapolis to Chicago Union Stationtrain train Cardinal
    2. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train Lake Shore Limited
    17h 44m
    $203–512

Indianapolis to Buffalo by bus

Calendar7Weekly Buses
Duration10h 50mAverage Duration
Ticket$51Cheapest Price
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Questions & Answers

What companies run services between Indianapolis, IN, USA and Buffalo, NY, USA?

Southwest Airlines, Delta, and two other airlines fly from Indianapolis (IND) to Buffalo Niagara International Airport (BUF) hourly. Alternatively, you can take a bus from Indianapolis, IN to Buffalo, NY via Toledo and Cleveland, OH in around 10h 50m.

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