There are 10 ways to get from Indiana to Ithaca by train, plane, bus, bus (Greyhound, Flixbus), car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Chicago O'Hare International Airport, fly to Syracuse Hancock International Airport, bus
best- Take the train from Gary to Van Buren St.
- Fly from Chicago O'Hare International Airport (ORD) to Syracuse Hancock International Airport (SYR)ORD - SYR
- Take the bus from Syracuse Airport, NY to Ithaca, NY
7h 28m$125–668Bus, train
cheapest- Take the bus from Indianapolis, IN to Toledo
- Take the train from Toledo to Rochester
- Take the bus from Rochester to Ithaca231
14h 14m$87–200Bus
- Take the bus from Indianapolis Union Station to Cincinnati Bus Station
- Take the bus from Cincinnati, OH to Buffalo, NY
- Take the bus from Buffalo to Ithaca
17h$98–196Drive 620.7 mi
- Drive from Indianapolis to Ithaca620.7 mi
11h 8m$114–164Train to Chicago O'Hare International Airport, fly to Rochester, bus
- Take the train from Gary to Van Buren St.
- Fly from Chicago O'Hare International Airport (ORD) to Rochester (ROC)ORD - ROC
- Take the bus from Rochester, NY to Ithaca, NY
8h 2m$140–533Train to Chicago Midway International Airport, fly to Rochester, bus
- Take the train from Gary to Museum Campus/11th Street Sation
- Fly from Chicago Midway International Airport (MDW) to Rochester (ROC)MDW - ROC
- Take the bus from Rochester, NY to Ithaca, NY
7h 39m$119–673Train to Chicago O'Hare International Airport, fly to Wilkes-Barre/Scranton International Airport, bus
- Take the train from Gary to Van Buren St.
- Fly from Chicago O'Hare International Airport (ORD) to Wilkes-Barre/Scranton International Airport (AVP)ORD - AVP
- Take the bus from Scranton, Pa to Ithaca
8h 29m$132–513Train to Chicago Midway International Airport, fly to Buffalo Niagara International Airport, bus
- Take the train from Gary to Museum Campus/11th Street Sation
- Fly from Chicago Midway International Airport (MDW) to Buffalo Niagara International Airport (BUF)MDW - BUF
- Take the bus from Buffalo Niagara International Airport to Ithaca
8h 24m$239–1,368Train, bus
- Take the train from Indianapolis to Chicago Union Station
- Take the train from Chicago Union Station to Syracuse Regional Transportation Center
- Take the bus from Syracuse Bus Station to Ithaca
21h 2m$149–295Bus via Harrisburg
- Take the bus from Indianapolis Union Station to Harrisburg Bus Station
- Take the bus from Harrisburg, PA to Scranton, PA
- Take the bus from Scranton, Pa to Ithaca246
21h 40m$103–269
Indiana to Ithaca by bus and train
Questions & Answers
The cheapest way to get from Indiana to Ithaca is to drive which costs $110 - $170 and takes 11h 8m.
The fastest way to get from Indiana to Ithaca is to train and fly and bus which takes 7h 28m and costs $120 - $700.
No, there is no direct bus from Indiana station to Ithaca. However, there are services departing from Indianapolis Union Station and arriving at Ithaca via Cincinnati, OH and Buffalo. The journey, including transfers, takes approximately 17h.
The distance between Indiana and Ithaca is 722 miles. The road distance is 624.4 miles.
The best way to get from Indiana to Ithaca without a car is to bus and train which takes 14h 14m and costs $85 - $200.
It takes approximately 7h 28m to get from Indiana to Ithaca, including transfers.
Indiana to Ithaca bus services, operated by Greyhound USA, depart from Indianapolis Union Station.
Indiana to Ithaca bus services, operated by Greyhound USA, arrive at Cincinnati Bus Station.
Yes, the driving distance between Indiana to Ithaca is 624 miles. It takes approximately 11h 8m to drive from Indiana to Ithaca.
Book your Indiana to Ithaca bus tickets online with Omio.
What companies run services between Indiana, USA and Ithaca, NY, USA?
You can take a bus from Indianapolis Union Station to Ithaca via Cincinnati Bus Station, Cincinnati, OH, Buffalo, NY, and Buffalo in around 17h.
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Syracuse Hancock International Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- $95–600
Flights from Chicago O'Hare International Airport to Syracuse Hancock International Airport via Reagan Washington
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $120–700
Flights from Chicago O'Hare International Airport to Rochester
- Ave. Duration
- 1h 47m
- When
- Every day
- Estimated price
- $70–450
Flights from Chicago O'Hare International Airport to Rochester via Reagan Washington
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $100–550
Flights from Chicago O'Hare International Airport to Wilkes-Barre/Scranton International Airport
- Ave. Duration
- 2h 2m
- When
- Every day
- Estimated price
- $65–390
Flights from Chicago O'Hare International Airport to Wilkes-Barre/Scranton International Airport via Charlotte
- Ave. Duration
- 4h 42m
- When
- Thursday, Saturday, and Sunday
- Estimated price
- $95–490
- Website
- united.com
Flights from Chicago O'Hare International Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 56m
- When
- Every day
- Estimated price
- $95–600
Flights from Chicago O'Hare International Airport to Syracuse Hancock International Airport via Washington Dulles
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $120–700
Flights from Chicago O'Hare International Airport to Rochester
- Ave. Duration
- 1h 49m
- When
- Every day
- Estimated price
- $70–450
Flights from Chicago O'Hare International Airport to Rochester via Washington Dulles
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- $95–550
Flights from Chicago O'Hare International Airport to Wilkes-Barre/Scranton International Airport
- Ave. Duration
- 2h 4m
- When
- Every day
- Estimated price
- $65–390
Flights from Chicago O'Hare International Airport to Wilkes-Barre/Scranton International Airport via Washington Dulles
- Ave. Duration
- 4h 42m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $75–420
- Website
- southwest.com
Flights from Chicago Midway International Airport to Rochester
- Ave. Duration
- 1h 35m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $90–600
Flights from Chicago Midway International Airport to Rochester via Baltimore
- Ave. Duration
- 4h
- When
- Saturday
- Estimated price
- $120–700
Flights from Chicago Midway International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $200–1,300
- Website
- delta.com
Flights from Chicago O'Hare International Airport to Syracuse Hancock International Airport via Detroit
- Ave. Duration
- 4h 19m
- When
- Every day
- Estimated price
- $95–600
Flights from Chicago O'Hare International Airport to Syracuse Hancock International Airport via New York La Guardia
- Ave. Duration
- 4h 35m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–700
Flights from Chicago O'Hare International Airport to Rochester via Detroit
- Ave. Duration
- 3h 49m
- When
- Every day
- Estimated price
- $70–450
- Phone
- +1 219-926-5744
- Website
- mysouthshoreline.com
Train from Gary to Van Buren St.
- Ave. Duration
- 52 min
- Frequency
- Hourly
- Estimated price
- $7–9
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $7–9
Train from Gary to Museum Campus/11th Street Sation
- Ave. Duration
- 49 min
- Frequency
- Hourly
- Estimated price
- $7–8
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $7–8
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Toledo to Rochester
- Ave. Duration
- 6h 29m
- Frequency
- Twice daily
- Estimated price
- $45–85
- Website
- https://www.amtrak.com/home.html
Train from Indianapolis to Chicago Union Station
- Ave. Duration
- 5h
- Frequency
- 3 times a week
- Estimated price
- $40–65
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Syracuse Regional Transportation Center
- Ave. Duration
- 12h 58m
- Frequency
- Twice daily
- Estimated price
- $90–200
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-844-800-6828
- pr@ourbus.com
- Website
- ourbus.com
Bus from Syracuse Airport, NY to Ithaca, NY
- Ave. Duration
- 1h 45m
- Frequency
- 5 times a week
- Estimated price
- $20–55
- Website
- https://www.ourbus.com
Bus from Rochester, NY to Ithaca, NY
- Ave. Duration
- 2h 30m
- Frequency
- 6 times a week
- Estimated price
- $20–60
- Website
- https://www.ourbus.com
Bus from Harrisburg, PA to Scranton, PA
- Ave. Duration
- 3h 15m
- Frequency
- Once daily
- Estimated price
- $20–65
- Website
- https://www.ourbus.com
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Indianapolis, IN to Toledo
- Ave. Duration
- 3h 55m
- Frequency
- Once daily
- Estimated price
- $21–65
- Website
- https://baronsbus.com
Bus from Cincinnati, OH to Buffalo, NY
- Ave. Duration
- 9h 20m
- Frequency
- Once daily
- Estimated price
- $45–95
- Website
- https://baronsbus.com
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Rochester to Ithaca
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $20–55
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $20–55
- Flexible
- $40–55
Bus from Scranton, Pa to Ithaca
- Ave. Duration
- 2h 30m
- Frequency
- Twice daily
- Estimated price
- $22–65
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $22–65
- Flexible
- $45–65
Bus from Harrisburg, PA to Scranton, PA
- Ave. Duration
- 3h 15m
- Frequency
- Once daily
- Estimated price
- $24–75
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $24–75
- Flexible
- $45–75
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Indianapolis Union Station to Cincinnati Bus Station
- Ave. Duration
- 1h 55m
- Frequency
- Once daily
- Estimated price
- $23–50
- Website
- https://www.greyhound.com/
Bus from Indianapolis Union Station to Harrisburg Bus Station
- Ave. Duration
- 13h 55m
- Frequency
- 3 times a day
- Estimated price
- $60–130
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Buffalo to Ithaca
- Ave. Duration
- 3h 45m
- Frequency
- 6 times a week
- Estimated price
- $30–55
- Schedules at
- flixbus.com
Bus from Buffalo Niagara International Airport to Ithaca
- Ave. Duration
- 3h 25m
- Frequency
- 6 times a week
- Estimated price
- $30–55
- Schedules at
- flixbus.com
Bus from Syracuse Bus Station to Ithaca
- Ave. Duration
- 1h 4m
- Frequency
- Once daily
- Estimated price
- $15–30
- Schedules at
- flixbus.com
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