There are 9 ways to get from Indiana to Des Moines by train, plane, bus (Greyhound), bus, car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Chicago O'Hare International Airport, fly to Des Moines
best- Take the train from Gary to Van Buren St.
- Fly from Chicago O'Hare International Airport (ORD) to Des Moines (DSM)ORD - DSM
4h 27m$107–584Train to Chicago O'Hare International Airport, fly to Fort Dodge Municipal Airport, drive
cheapest- Take the train from Gary to Van Buren St.
- Fly from Chicago O'Hare International Airport (ORD) to Fort Dodge Municipal Airport (FOD)ORD - FOD
- Drive from Fort Dodge Municipal Airport (FOD) to Des Moines
6h 19m$66–318Bus (Greyhound)
- Take the bus from Indianapolis Union Station to Chicago Bus StationGreyhound US0100 / ...
- Take the bus from Chicago Bus Station to Des MoinesGreyhound US0123 / ...
11h 14m$81–178Train, bus via Galesburg
- Take the train from Indianapolis to Chicago Union Station
- Take the train from Chicago Union Station to Galesburg Amtrak Station
- Take the bus from Galesburg to Burlington
- Take the bus from Burlington to Des Moines
14h 51m$131–471Drive 466.6 mi
- Drive from Indianapolis to Des Moines466.6 mi
7h 50m$86–123Train to Chicago Midway International Airport, fly to Des Moines
- Take the train from Gary to Museum Campus/11th Street Sation
- Fly from Chicago Midway International Airport (MDW) to Des Moines (DSM)MDW - DSM
4h 10m$126–734Train to South Bend, fly to Des Moines
- Take the train from Gary Metro Center to South Bend Airport
- Fly from South Bend (SBN) to Des Moines (DSM)SBN - DSM
6h 26m$177–982Bus via Des Moines
- Take the bus from Indianapolis to Chicago Bus StationFlixBus 2512 / ...
- Take the bus from Chicago to Des MoinesChicago
11h 45m$92–233Train, bus
- Take the train from Indianapolis to Chicago Union StationCardinal
- Take the bus from Chicago to Des MoinesChicago
13h 19m$91–416
Indiana to Des Moines by bus (Greyhound)
Questions & Answers
The cheapest way to get from Indiana to Des Moines is to drive which costs $85 - $130 and takes 7h 50m.
The fastest way to get from Indiana to Des Moines is to train and fly which takes 4h 10m and costs $120 - $750.
No, there is no direct bus from Indiana station to Des Moines. However, there are services departing from Indianapolis Union Station and arriving at Des Moines via Chicago Bus Station. The journey, including transfers, takes approximately 11h 14m.
The distance between Indiana and Des Moines is 354 miles. The road distance is 469.3 miles.
The best way to get from Indiana to Des Moines without a car is to bus which takes 11h 14m and costs $80 - $180.
It takes approximately 4h 27m to get from Indiana to Des Moines, including transfers.
Indiana to Des Moines bus services, operated by Greyhound USA, depart from Indianapolis Union Station.
Indiana to Des Moines bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Des Moines is 1h behind Indiana. It is currently 11:14 AM in Indiana and 10:14 AM in Des Moines.
Yes, the driving distance between Indiana to Des Moines is 469 miles. It takes approximately 7h 50m to drive from Indiana to Des Moines.
What companies run services between Indiana, USA and Des Moines, IA, USA?
You can take a bus from Indianapolis Union Station to Des Moines via Chicago Bus Station in around 11h 14m.
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Des Moines
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $80–550
Flights from South Bend to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 7h 22m
- When
- Every day
- Estimated price
- $340–1,600
Flights from South Bend to Des Moines via Charlotte
- Ave. Duration
- 7h
- When
- Every day
- Estimated price
- $320–1,500
- Website
- united.com
Flights from Chicago O'Hare International Airport to Des Moines
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $80–550
Flights from South Bend to Des Moines via Chicago O'Hare International Airport
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- $150–950
Flights from Chicago O'Hare International Airport to Fort Dodge Municipal Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $40–280
- Website
- delta.com
Flights from South Bend to Des Moines via Detroit
- Ave. Duration
- 4h 3m
- When
- Friday to Sunday
- Estimated price
- $200–1,100
Flights from South Bend to Des Moines via Minneapolis
- Ave. Duration
- 4h 14m
- When
- Every day
- Estimated price
- $200–1,100
Flights from South Bend to Des Moines via Atlanta
- Ave. Duration
- 5h 45m
- When
- Every day
- Estimated price
- $310–1,500
- Website
- southwest.com
Flights from Chicago Midway International Airport to Des Moines
- Ave. Duration
- 1h 25m
- When
- Monday, Thursday, and Friday
- Estimated price
- $100–700
Flights from Chicago Midway International Airport to Des Moines via St. Louis
- Ave. Duration
- 3h 50m
- When
- Monday and Friday
- Estimated price
- $130–800
- Phone
- +1 219-926-5744
- Website
- mysouthshoreline.com
Train from Gary to Van Buren St.
- Ave. Duration
- 52 min
- Frequency
- Hourly
- Estimated price
- $7–9
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $7–9
Train from Gary to Museum Campus/11th Street Sation
- Ave. Duration
- 49 min
- Frequency
- Hourly
- Estimated price
- $7–8
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $7–8
Train from Gary Metro Center to South Bend Airport
- Ave. Duration
- 1h 12m
- Frequency
- Every 2 hours
- Estimated price
- $10–12
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $10–12
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Indianapolis to Chicago Union Station
- Ave. Duration
- 5h
- Frequency
- 3 times a week
- Estimated price
- $35–260
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Galesburg Amtrak Station
- Ave. Duration
- 2h 36m
- Frequency
- 4 times a day
- Estimated price
- $30–85
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Indianapolis Union Station to Chicago Bus Station
- Ave. Duration
- 3h 40m
- Frequency
- 5 times a day
- Estimated price
- $35–85
- Website
- https://www.greyhound.com/
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 6h 34m
- Frequency
- 3 times a day
- Estimated price
- $45–95
- Website
- https://www.greyhound.com/
- Phone
- +1 (319) 753-2864
- info@burlingtontrailways.com
- Website
- burlingtontrailways.com
Bus from Galesburg to Burlington
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $25–50
- Website
- https://burlingtontrailways.com
- Saver Fares
- $25–40
- Flexible Fares
- $30–50
Bus from Burlington to Des Moines
- Ave. Duration
- 3h 5m
- Frequency
- Once daily
- Estimated price
- $40–80
- Website
- https://burlingtontrailways.com
- Saver Fares
- $40–60
- Flexible Fares
- $50–80
Bus from Chicago to Des Moines
- Ave. Duration
- 7h 10m
- Frequency
- Twice daily
- Estimated price
- $55–160
- Website
- https://burlingtontrailways.com
- Saver Fares
- $65–95
- Flexible Fares
- $90–130
- Saver Fare
- $55–110
- Flex Fare
- $75–160
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Indianapolis to Chicago Bus Station
- Ave. Duration
- 3h 35m
- Frequency
- Every 4 hours
- Estimated price
- $35–75
- Schedules at
- flixbus.com
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