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How to get fromIndiana to Buffaloby train, plane, bus, bus (Greyhound), car, shuttle, bus (Flixbus) or train (Amtrak)

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There are 9 ways to get from Indiana to Buffalo by train, plane, bus, bus (Greyhound), car, shuttle, bus (Flixbus), or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Chicago Midway International Airport, fly to Buffalo Niagara International Airport

    best
    1. Take the train from Gary to Museum Campus/11th Street Sationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Buffalo Niagara International Airport (BUF)plane plane MDW - BUF
    5h 13m
    $203–1,293

  2. Bus, train

    cheapest
    1. Take the bus from Indianapolis, IN to Toledobus bus Cincinnati
    2. Take the train from Toledo to Buffalo Depew Stationtrain train Lake Shore Limited
    11h 38m
    $53–275

  3. Bus

    1. Take the bus from Indianapolis Union Station to Cincinnati Bus Stationbus bus Greyhound US0120
    2. Take the bus from Cincinnati, OH to Buffalo, NYbus bus Cinncinati,OH-Buffalo
    12h 15m
    $72–169

  4. Drive 494.8 mi

    1. Drive from Indianapolis to Buffalocar car 494.8 mi
    8h 33m
    $91–131

  5. Train to Chicago O'Hare International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Gary to Van Buren St.train train
    2. Fly from Chicago O'Hare International Airport (ORD) to Buffalo Niagara International Airport (BUF)plane plane ORD - BUF
    5h 45m
    $154–943

  6. Train to Chicago Midway International Airport, fly to Rochester, bus

    1. Take the train from Gary to Museum Campus/11th Street Sationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Rochester (ROC)plane plane MDW - ROC
    3. Take the bus from Rochester, NY to Buffalo, NYbus bus
    7h 23m
    $133–798

  7. Fly Indianapolis to Toronto Pearson International Airport, shuttle

    1. Fly from Indianapolis (IND) to Toronto Pearson International Airport (YYZ)plane plane IND - YYZ
    2. Take a shuttle bus from Pearson International Airport Terminal 1 to Buffalo Airportshuttle bus
    8h 5m
    $266–652

  8. Bus via Pittsburgh

    1. Take the bus from Indianapolis to Pittsburgh Intermodal Stationbus bus FlixBus N2640
    2. Take the bus from Pittsburgh to Buffalobus bus Fab510
    15h 50m
    $84–260

  9. Train (Amtrak)

    1. Take the train from Indianapolis to Chicago Union Stationtrain train Cardinal
    2. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train Lake Shore Limited
    17h 44m
    $100–348

Indiana to Buffalo by bus and train

Calendar7Weekly Services
Duration11h 38mAverage Duration
Ticket$53Cheapest Price
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Questions & Answers

What companies run services between Indiana, USA and Buffalo, NY, USA?

You can take a bus from Indianapolis Union Station to Buffalo, NY via Cincinnati Bus Station and Cincinnati, OH in around 12h 15m. Alternatively, you can take a train from Indianapolis to Buffalo via Chicago Union Station and Buffalo Depew Station in around 17h 44m.

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