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How to get fromIndiana to Buffaloby train, plane, bus, bus (Greyhound), car, bus (Flixbus) or train (Amtrak)

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There are 9 ways to get from Indiana to Buffalo by train, plane, bus, bus (Greyhound), car, bus (Flixbus), or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Chicago Midway International Airport, fly to Buffalo Niagara International Airport

    best
    1. Take the train from Gary to Museum Campus/11th Street Sationtrain
    2. Fly from Chicago Midway International Airport (MDW) to Buffalo Niagara International Airport (BUF)planeMDW - BUF
    5h 13m
    $193–1,193

  2. Bus, train

    cheapest
    1. Take the bus from Indianapolis, IN to ToledobusCincinnati
    2. Take the train from Toledo to Buffalo Depew StationtrainLake Shore Limited
    11h 38m
    $66–255

  3. Bus

    1. Take the bus from Indianapolis Union Station to Cincinnati Bus StationbusGreyhound US0120
    2. Take the bus from Cincinnati, OH to Buffalo, NYbusCinncinati,OH-Buffalo
    12h 15m
    $68–170

  4. Drive 494.8 mi

    1. Drive from Indianapolis to Buffalocar494.8 mi
    8h 29m
    $91–131

  5. Train to Chicago O'Hare International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Gary to Van Buren St.train
    2. Fly from Chicago O'Hare International Airport (ORD) to Buffalo Niagara International Airport (BUF)planeORD - BUF
    5h 44m
    $164–993

  6. Train to Chicago O'Hare International Airport, fly to Rochester, bus

    1. Take the train from Gary to Van Buren St.train
    2. Fly from Chicago O'Hare International Airport (ORD) to Rochester (ROC)planeORD - ROC
    3. Take the bus from Rochester, NY to Buffalo, NYbus
    7h 56m
    $144–618

  7. Train to Chicago Midway International Airport, fly to Rochester, bus

    1. Take the train from Gary to Museum Campus/11th Street Sationtrain
    2. Fly from Chicago Midway International Airport (MDW) to Rochester (ROC)planeMDW - ROC
    3. Take the bus from Rochester, NY to Buffalo, NYbus
    7h 23m
    $133–748

  8. Bus via Pittsburgh

    1. Take the bus from Indianapolis to Pittsburgh Intermodal StationbusFlixBus N2640
    2. Take the bus from Pittsburgh to BuffalobusFab510
    15h 50m
    $84–261

  9. Train (Amtrak)

    1. Take the train from Indianapolis to Chicago Union StationtrainCardinal
    2. Take the train from Chicago Union Station to Buffalo Depew StationtrainLake Shore Limited
    17h 44m
    $100–582

Indiana to Buffalo by bus and train

Calendar7Weekly Services
Duration11h 38mAverage Duration
Ticket$66Cheapest Price
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Questions & Answers

What companies run services between Indiana, USA and Buffalo, NY, USA?

You can take a bus from Indianapolis Union Station to Buffalo, NY via Cincinnati Bus Station and Cincinnati, OH in around 12h 15m. Alternatively, you can take a train from Indianapolis to Buffalo via Chicago Union Station and Buffalo Depew Station in around 17h 44m.

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