Rome2Rio

How to get fromIndiana to Buffaloby train, plane, bus (Flixbus), bus, car, bus (Greyhound), or train (Amtrak)

Find Transport to Buffalo

See all options

There are 9 ways to get from Indiana to Buffalo by train, plane, bus (Flixbus), bus, car, bus (Greyhound), or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Chicago Midway International Airport, fly to Buffalo Niagara International Airport

    best
    1. Take the train from Gary to Museum Campus/11th Street Sationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Buffalo Niagara International Airport (BUF)plane plane MDW - BUF
    5h 13m
    $171–327

  2. Bus (Flixbus)

    cheapest
    1. Take the bus from Indianapolis to Columbusbus bus FlixBus 2511 / ...
    2. Take the bus from Columbus to Buffalobus bus FlixBus 2526
    10h 55m
    $77–115

  3. Bus, train

    1. Take the bus from Indianapolis, IN to Toledobus bus Cincinnati / ...
    2. Take the train from Toledo to Buffalo Depew Stationtrain train Lake Shore Limited
    11h 38m
    $94–370

  4. Drive  494.8 mi

    1. Drive from Indianapolis to Buffalocar car 494.8 mi
    8h 38m
    $91–131

  5. Train to Chicago O'Hare International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Gary to Van Buren St.train train
    2. Fly from Chicago O'Hare International Airport (ORD) to Buffalo Niagara International Airport (BUF)plane plane ORD - BUF
    5h 39m
    $181–317

  6. Train to Chicago Midway International Airport, fly to Rochester, bus

    1. Take the train from Gary to Museum Campus/11th Street Sationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Rochester (ROC)plane plane MDW - ROC
    3. Take the bus from Rochester Bus Stop to Buffalobus bus
    6h 42m
    $179–905

  7. Fly Indianapolis to Toronto Pearson International Airport, bus

    1. Fly from Indianapolis (IND) to Toronto Pearson International Airport (YYZ)plane plane IND - YYZ
    2. Take the bus from Toronto Pearson Airport to Buffalobus bus
    8h 28m
    $77–405

  8. Bus via Brook Park (Greyhound)

    1. Take the bus from Indianapolis Union Station to Dayton Trotwood Bus Stationbus bus
    2. Take the bus from Dayton Trotwood Bus Station to Cleveland Bus Stationbus bus
    3. Take the bus from Cleveland Bus Station to Buffalobus bus
    12h 50m
    $82–136

  9. Train (Amtrak)

    1. Take the train from Indianapolis to Chicago Union Stationtrain train Cardinal
    2. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train Lake Shore Limited
    17h 44m
    $181–562

Indiana to Buffalo by bus (Flixbus)

Calendar6Weekly Buses
Duration10h 55mAverage Duration
Ticket$77Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Indiana to Buffalo.ExpandLaunch map view
  • Distance: 516.1 mi
  • Duration: 5h 13m

What companies run services between Indiana, USA and Buffalo, NY, USA?

You can take a bus from Indianapolis to Buffalo via Columbus in around 10h 55m. Alternatively, you can take a train from Indianapolis to Buffalo via Chicago Union Station and Buffalo Depew Station in around 17h 44m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There