Rome2Rio

How to get fromIndiana to Buffaloby train, plane, bus (Greyhound), bus, car, bus (Flixbus) or train (Amtrak)

Find Transport to Buffalo

See all options

There are 8 ways to get from Indiana to Buffalo by train, plane, bus (Greyhound), bus, car, bus (Flixbus), or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Chicago O'Hare International Airport, fly to Buffalo Niagara International Airport

    best
    1. Take the train from Gary to Van Buren St.train train
    2. Fly from Chicago O'Hare International Airport (ORD) to Buffalo Niagara International Airport (BUF)plane plane ORD - BUF
    5h 45m
    $134–893

  2. Bus via Toledo

    cheapest
    1. Take the bus from Indianapolis, IN to Toledobus bus
    2. Take the bus from Toledo Bus Stop to Cleveland Bus Stationbus bus
    3. Take the bus from Cleveland, OH to Buffalo, NYbus bus
    10h 50m
    $51–165

  3. Bus, train

    1. Take the bus from Indianapolis, IN to Toledobus bus Cincinnati
    2. Take the train from Toledo to Buffalo Depew Stationtrain train Lake Shore Limited
    11h 38m
    $53–230

  4. Drive 494.8 mi

    1. Drive from Indianapolis to Buffalocar car 494.8 mi
    8h 38m
    $91–131

  5. Train to Chicago Midway International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Gary to Museum Campus/11th Street Sationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Buffalo Niagara International Airport (BUF)plane plane MDW - BUF
    5h 13m
    $183–1,193

  6. Train to Chicago Midway International Airport, fly to Rochester, bus

    1. Take the train from Gary to Museum Campus/11th Street Sationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Rochester (ROC)plane plane MDW - ROC
    3. Take the bus from Rochester, NY to Buffalo, NYbus bus
    7h 23m
    $143–848

  7. Bus

    1. Take the bus from Indianapolis to Pittsburgh Intermodal Stationbus bus FlixBus N2640
    2. Take the bus from Pittsburgh to Buffalobus bus Fab510
    15h 50m
    $82–273

  8. Train (Amtrak)

    1. Take the train from Indianapolis to Chicago Union Stationtrain train Cardinal
    2. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train Lake Shore Limited
    17h 44m
    $98–309

Indiana to Buffalo by bus

Calendar7Weekly Buses
Duration10h 50mAverage Duration
Ticket$51Cheapest Price
See schedules

Questions & Answers

What companies run services between Indiana, USA and Buffalo, NY, USA?

You can take a bus from Indianapolis, IN to Buffalo, NY via Toledo Bus Stop, Cleveland Bus Station, and Cleveland, OH in around 10h 50m. Alternatively, you can take a train from Indianapolis to Buffalo via Chicago Union Station and Buffalo Depew Station in around 17h 44m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers

Where to next?

Trips from Indiana

Trips to Buffalo

Popular routes