There are 9 ways to get from Illinois to Tupelo by plane, car, bus (Greyhound, Flixbus), bus, train, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Chicago Midway International Airport to Birmingham–Shuttlesworth International Airport, drive
best- Fly from Chicago Midway International Airport (MDW) to Birmingham–Shuttlesworth International Airport (BHM)plane MDW - BHM
- Drive from Birmingham-Airport-BHM to Tupelocar
5h 36m$156–845Fly Chicago O'Hare International Airport to Huntsville International Airport-Carl T Jones Field, drive
cheapest- Fly from Chicago O'Hare International Airport (ORD) to Huntsville International Airport-Carl T Jones Field (HSV)plane ORD - HSV
- Drive from Huntsville International Airport-Carl T Jones Field (HSV) to Tupelocar
6h 5m$106–520Bus
- Take the bus from Chicago Bus Station to Memphis Bus Stationbus Greyhound US0125
- Take the bus from Memphis Bus Station to Tupelobus Greyhound US0610
12h 14m$112–245Drive 583 mi
- Drive from Chicago to Tupelocar 583 mi
10h 33m$107–154Fly Chicago O'Hare International Airport to Memphis, bus
- Fly from Chicago O'Hare International Airport (ORD) to Memphis (MEM)plane ORD - MEM
- Take the bus from Memphis Bus Station to Tupelobus
7h 40m$282–548Fly Chicago Midway International Airport to Tupelo Regional Airport
- Fly from Chicago Midway International Airport (MDW) to Tupelo Regional Airport (TUP)plane MDW - TUP
6h 18m$128–675Fly Chicago Midway International Airport to Memphis, bus
- Fly from Chicago Midway International Airport (MDW) to Memphis (MEM)plane MDW - MEM
- Take the bus from Memphis Bus Station to Tupelobus
7h 23m$152–778Train, bus
- Take the train from Chicago Union Station to St. Louistrain
- Take the bus from St Louis Bus Station to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Tupelobus
14h$114–240Bus via Champaign
- Take the bus from Chicago to Champaign Intermodal Trans Ctrbus
- Take the bus from Champaign Intermodal Trans Ctr to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Tupelobus
16h 17m$118–214
Chicago Midway International Airport (MDW) to Birmingham–Shuttlesworth International Airport (BHM) flights
Questions & Answers
The cheapest way to get from Illinois to Tupelo is to drive which costs $100 - $160 and takes 10h 33m.
The fastest way to get from Illinois to Tupelo is to fly and drive which takes 5h 36m and costs $150 - $850.
The distance between Illinois and Tupelo is 721 miles. The road distance is 586.4 miles.
The best way to get from Illinois to Tupelo without a car is to bus which takes 12h 14m and costs $110 - $250.
It takes approximately 5h 36m to get from Illinois to Tupelo, including transfers.
The best way to get from Illinois to Tupelo is to bus which takes 12h 14m and costs $110 - $250. Alternatively, you can fly, which costs $120 - $700 and takes 6h 18m.
Yes, the driving distance between Illinois to Tupelo is 586 miles. It takes approximately 10h 33m to drive from Illinois to Tupelo.
There are 34+ hotels available in Tupelo.
What companies run services between Illinois, USA and Tupelo, MS, USA?
You can take a bus from Chicago Bus Station to Tupelo via Memphis Bus Station and Tupelo in around 12h 14m. Alternatively, Southwest Airlines and Corporate Flight Management Inc fly from Chicago Midway International Airport (MDW) to Tupelo Regional Airport (TUP) once daily.
- Website
- delta.com
Flights from Chicago Midway International Airport to Birmingham–Shuttlesworth International Airport via Atlanta
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $150–850
Flights from Chicago O'Hare International Airport to Huntsville International Airport-Carl T Jones Field via Atlanta
- Ave. Duration
- 4h 14m
- When
- Every day
- Estimated price
- $100–550
Flights from Chicago O'Hare International Airport to Memphis via Atlanta
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- $110–600
Flights from Chicago Midway International Airport to Memphis via Detroit
- Ave. Duration
- 4h 29m
- When
- Saturday
- Estimated price
- $150–800
- Website
- southwest.com
Flights from Chicago Midway International Airport to Birmingham–Shuttlesworth International Airport
- Ave. Duration
- 1h 43m
- When
- Every day
- Estimated price
- $130–800
Flights from Chicago Midway International Airport to Birmingham–Shuttlesworth International Airport via Nashville
- Ave. Duration
- 3h 45m
- When
- Tuesday and Saturday
- Estimated price
- $130–800
Flights from Chicago O'Hare International Airport to Memphis via Nashville
- Ave. Duration
- 4h 5m
- When
- Saturday
- Estimated price
- $85–500
Flights from Chicago Midway International Airport to Memphis
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- $110–700
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Huntsville International Airport-Carl T Jones Field
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- $80–480
Flights from Chicago O'Hare International Airport to Memphis
- Ave. Duration
- 1h 54m
- When
- Every day
- Estimated price
- $75–470
- Website
- united.com
Flights from Chicago O'Hare International Airport to Huntsville International Airport-Carl T Jones Field
- Ave. Duration
- 1h 58m
- When
- Every day
- Estimated price
- $80–480
Flights from Chicago O'Hare International Airport to Memphis
- Ave. Duration
- 1h 59m
- When
- Every day
- Estimated price
- $75–470
- Website
- contouraviation.com
Flights from Chicago Midway International Airport to Tupelo Regional Airport via Nashville
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- $110–650
Flights from Chicago Midway International Airport to Tupelo Regional Airport via Indianapolis, Nashville
- Ave. Duration
- 9h 5m
- When
- Sunday
- Estimated price
- $110–650
Flights from Chicago Midway International Airport to Tupelo Regional Airport via Louisville, Nashville
- Ave. Duration
- 9h 10m
- When
- Sunday
- Estimated price
- $110–700
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to St. Louis
- Ave. Duration
- 4h 46m
- Frequency
- 5 times a day
- Estimated price
- $30–110
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Chicago Bus Station to Memphis Bus Station
- Ave. Duration
- 9h 30m
- Frequency
- Once daily
- Estimated price
- $75–180
- Website
- https://www.greyhound.com/
Bus from Memphis Bus Station to Tupelo
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $29–60
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Memphis Bus Station
- Ave. Duration
- 5h 30m
- Frequency
- Once daily
- Estimated price
- $40–65
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Chicago Bus Station to Memphis Bus Station
- Ave. Duration
- 11h
- Frequency
- 5 times a week
- Estimated price
- $70–150
- Schedules at
- flixbus.com
Bus from St Louis Bus Station to Memphis Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- 5 times a week
- Estimated price
- $40–60
- Schedules at
- flixbus.com
Bus from Chicago to Champaign Intermodal Trans Ctr
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $22–40
- Schedules at
- flixbus.com
Bus from Champaign Intermodal Trans Ctr to Memphis Bus Station
- Ave. Duration
- 8h 25m
- Frequency
- 5 times a week
- Estimated price
- $55–100
- Schedules at
- flixbus.com
- Adult
- $55–100
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