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How to get fromHyannis to Presque Isleby plane, bus (Amtrak), car, bus (Flixbus, Greyhound), bus or train

Find Transport to Presque Isle

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There are 5 ways to get from Hyannis to Presque Isle by plane, bus (Amtrak), car, bus (Flixbus, Greyhound), bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Barnstable Municipal Airport (HYA) to Presque Isle (PQI)plane plane HYA - PQI
    5h 59m
    $78–454
  2. Bus

    cheapest
    1. Take the bus from Hyannis Transportation Center to Boston South Stationbus bus
    2. Take the bus from Boston, MA - South Station to Bangor Transportation Centerbus bus
    3. Take the bus from Bangor, ME to Presque Isle, Mainebus bus
    11h 7m
    $76–141
  3. Drive 461.1 mi

    1. Drive from Hyannis to Presque Islecar car 461.1 mi
    8h 10m
    $85–122
  4. Bus via Bangor

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to Bangor Park & Ridebus bus
    3. Take the bus from Bangor, ME to Presque Isle, Mainebus bus
    12h 50m
    $80–149
  5. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Stationbus bus
    2. Take the train from Boston to Portlandtrain train
    3. Take the bus from Portland Transportation Center to Bangor Transportation Centerbus bus
    4. Take the bus from Bangor, ME to Presque Isle, Mainebus bus
    12h 52m
    $89–179

Hyannis to Presque Isle by bus

Calendar7Weekly Buses
Duration11h 7mAverage Duration
Ticket$76Cheapest Price
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Questions & Answers

What companies run services between Hyannis, MA, USA and Presque Isle, ME, USA?

Cape Air, JetBlue Airways, and American Airlines fly from Barnstable Municipal Airport (HYA) to Presque Isle (PQI) 3 times a day. Alternatively, you can take a bus from Hyannis Transportation Center to Presque Isle, Maine via Boston South Station, Boston, MA - South Station, Bangor Transportation Center, and Bangor, ME in around 11h 7m.

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