Rome2Rio

How to get fromHyannis to Presque Isleby bus (Amtrak), car, ferry, plane, bus, train, or bus (Flixbus, Greyhound)

Find Transport to Presque Isle

See all options

There are 7 ways to get from Hyannis to Presque Isle by bus (Amtrak), car, ferry, plane, bus, train, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston, MA - South Station to Bangor Transportation Centerbus bus
    3. Take the bus from Bangor, ME to Presque Isle, Mainebus bus
    11h 16m
    $93–140

  2. Fly from Barnstable Municipal Airport

    cheapest
    1. Fly from Barnstable Municipal Airport (HYA) to Presque Isle (PQI)plane plane HYA - PQI
    8h
    $70–393

  3. Drive  461.1 mi

    1. Drive from Hyannis to Presque Islecar car 461.1 mi
    8h 10m
    $85–122

  4. Ferry to Martha'S Vineyard Airport, fly

    1. Take the ferry from Hyannis, MA to Marthas Vineyard Terminalferry ferry
    2. Fly from Martha'S Vineyard Airport (MVY) to Presque Isle (PQI)plane plane MVY - PQI
    8h 34m
    $94–461

  5. Bus, train

    1. Take the bus from Hyannis to Bostonbus bus
    2. Take the train from Boston to Portlandtrain train
    3. Take the bus from Portland Transportation Center to Bangor Transportation Centerbus bus
    4. Take the bus from Bangor, ME to Presque Isle, Mainebus bus
    12h 41m
    $128–207

  6. Bus via Bangor

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to Bangor Park & Ridebus bus
    3. Take the bus from Bangor, ME to Presque Isle, Mainebus bus
    12h 50m
    $89–144

  7. Bus to Boston Logan Airport, fly

    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Presque Isle (PQI)plane plane BOS - PQI
    4h 13m
    $77–405

Hyannis to Presque Isle by bus

Calendar7Weekly Buses
Duration11h 16mAverage Duration
Ticket$93Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Hyannis to Presque Isle.ExpandLaunch map view
  • Distance: 490.8 mi
  • Duration: 11h 16m

What companies run services between Hyannis, MA, USA and Presque Isle, ME, USA?

You can take a bus from Hyannis Transportation Center to Presque Isle, Maine via Boston, South Station, Boston, MA - South Station, Bangor Transportation Center, and Bangor, ME in around 11h 16m. Alternatively, Cape Air, JetBlue Airways, and American Airlines fly from Barnstable Municipal Airport (HYA) to Presque Isle (PQI) 4 times a day.

Airlines
Train operators
Bus operators
Ferry operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There