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How to get fromHyannis to Presque Isleby bus (Amtrak), car, plane, bus, train or bus (Greyhound)

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There are 5 ways to get from Hyannis to Presque Isle by bus (Amtrak), car, plane, bus, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Hyannis Transportation Center to Boston South Stationbus bus
    2. Take the bus from Boston, MA - South Station to Bangor Transportation Centerbus bus
    3. Take the bus from Bangor, ME to Presque Isle, Mainebus bus
    11h 7m
    $76–141

  2. Fly

    cheapest
    1. Fly from Barnstable Municipal Airport (HYA) to Presque Isle (PQI)plane plane HYA - PQI
    7h 55m
    $63–344

  3. Drive 461.1 mi

    1. Drive from Hyannis to Presque Islecar car 461.1 mi
    8h 10m
    $85–122

  4. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Stationbus bus
    2. Take the train from Boston to Portlandtrain train
    3. Take the bus from Portland Transportation Center to Bangor Transportation Centerbus bus
    4. Take the bus from Bangor, ME to Presque Isle, Mainebus bus
    12h 51m
    $97–158

  5. Bus via Bangor

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to Bangor Park & Ridebus bus
    3. Take the bus from Bangor, ME to Presque Isle, Mainebus bus
    13h 49m
    $88–144

Hyannis to Presque Isle by bus

Calendar7Weekly Buses
Duration11h 7mAverage Duration
Ticket$76Cheapest Price
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Questions & Answers

What companies run services between Hyannis, MA, USA and Presque Isle, ME, USA?

You can take a bus from Hyannis Transportation Center to Presque Isle, Maine via Boston South Station, Boston, MA - South Station, Bangor Transportation Center, and Bangor, ME in around 11h 7m. Alternatively, Cape Air, JetBlue Airways, and American Airlines fly from Barnstable Municipal Airport (HYA) to Presque Isle (PQI) 5 times a day.

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