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How to get fromHyannis to Ohioby bus, plane, bus (Greyhound), train, car, or bus (Flixbus)

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There are 8 ways to get from Hyannis to Ohio by bus, plane, bus (Greyhound), train, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, fly to Cleveland-Hopkins International Airport

    best
    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Cleveland-Hopkins International Airport (CLE)plane plane BOS - CLE
    5h 48m
    $171–989

  2. Drive  770.2 mi

    cheapest
    1. Drive from Hyannis to Columbuscar car 770.2 mi
    14h 28m
    $141–203

  3. Bus

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to Cleveland Bus Stationbus bus
    3. Take the bus from Cleveland Bus Station to Columbusbus bus
    20h 10m
    $147–275

  4. Bus, train via Brook Park

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the train from Boston to Cleveland Amtraktrain train
    3. Take the bus from Cleveland Bus Station to Columbusbus bus
    22h 25m
    $230–478

  5. Bus, fly to John Glenn Columbus International Airport

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to John Glenn Columbus International Airport (CMH)plane plane BOS - CMH
    6h 33m
    $190–989

  6. Bus, fly to Covington

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Covington (CVG)plane plane BOS - CVG
    7h 12m
    $451–1,041

  7. Bus via New York

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to New York Midtownbus bus
    3. Take the bus from New York Midtown to Columbusbus bus
    20h 45m
    $147–235

  8. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the train from Boston to Cleveland Amtraktrain train
    3. Take the bus from Cleveland Ohio Greyhound Station to Columbus, Ohio Greyhound Stationbus bus
    24h 35m
    $268–659

Hyannis to Ohio by bus

Calendar7Weekly Buses
Duration20h 10mAverage Duration
Ticket$147Cheapest Price
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Questions & Answers

Map of how to get from Hyannis to Ohio.ExpandLaunch map view
  • Distance: 648.1 mi
  • Duration: 5h 48m

What companies run services between Hyannis, MA, USA and Ohio, USA?

You can take a bus from Hyannis Transportation Center to Columbus via Boston, South Station, Boston, and Cleveland Bus Station in around 20h 10m.

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