There are 5 ways to get from Hyannis to Key West by bus, plane, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Boston Logan Airport, fly
best- Take the bus from Hyannis Transportation Center to Logan International Airportbus
- Fly from Boston Logan Airport (BOS) to Key West International Airport (EYW)plane BOS - EYW
7h 18m$139–529Bus, train
- Take the bus from Hyannis Transportation Center to Boston South Stationbus
- Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Miami Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
42h 50m$247–1,279Drive 1,675.8 mi
- Drive from Hyannis to Key Westcar 1,675.8 mi
29h 52m$306–442Fly from Barnstable Municipal Airport
- Fly from Barnstable Municipal Airport (HYA) to Key West International Airport (EYW)plane HYA - EYW
7h 14m$210–908Bus, train to Theodore Francis Green State Airport, fly
- Take the bus from Hyannis Transportation Center to Boston South Stationbus
- Take the train from South Station to TF Green Airporttrain
- Fly from Theodore Francis Green State Airport (PVD) to Key West International Airport (EYW)plane PVD - EYW
10h 47m$327–505
Boston Logan Airport (BOS) to Key West International Airport (EYW) flights
Questions & Answers
The cheapest way to get from Hyannis to Key West is to drive which costs $300 - $450 and takes 29h 52m.
The fastest way to get from Hyannis to Key West is to fly which takes 7h 14m and costs $210 - $950.
The distance between Hyannis and Key West is 1462 miles. The road distance is 1685.6 miles.
The best way to get from Hyannis to Key West without a car is to bus and train which takes 42h 50m and costs $240 - $1,300.
It takes approximately 7h 18m to get from Hyannis to Key West, including transfers.
Yes, the driving distance between Hyannis to Key West is 1686 miles. It takes approximately 29h 52m to drive from Hyannis to Key West.
There are 943+ hotels available in Key West.
What companies run services between Hyannis, MA, USA and Key West, FL, USA?
American Airlines, United Airlines, and Cape Air fly from Barnstable Municipal Airport (HYA) to Key West International Airport (EYW) 6 times a week.
- Website
- aa.com
Flights from Boston Logan Airport to Key West International Airport
- Ave. Duration
- 3h 58m
- When
- Friday to Sunday
- Estimated price
- $130–650
Flights from Boston Logan Airport to Key West International Airport via Miami
- Ave. Duration
- 6h 10m
- When
- Every day
- Estimated price
- $140–650
Flights from Barnstable Municipal Airport to Key West International Airport via Boston Logan Airport
- Ave. Duration
- 7h 42m
- When
- Friday to Sunday
- Estimated price
- $190–900
Flights from Barnstable Municipal Airport to Key West International Airport via Martha's Vineyard, Charlotte
- Ave. Duration
- 9h 39m
- When
- Saturday
- Estimated price
- $200–950
Flights from Barnstable Municipal Airport to Key West International Airport via Nantucket, Charlotte
- Ave. Duration
- 14h 42m
- When
- Saturday
- Estimated price
- $200–950
Flights from Theodore Francis Green State Airport to Key West International Airport via Charlotte
- Ave. Duration
- 7h 29m
- When
- Every day
- Estimated price
- $100–500
Flights from Theodore Francis Green State Airport to Key West International Airport via Reagan Washington
- Ave. Duration
- 6h 10m
- When
- Sunday
- Estimated price
- $100–490
- Website
- delta.com
Flights from Theodore Francis Green State Airport to Key West International Airport via Atlanta
- Ave. Duration
- 7h 33m
- When
- Every day
- Estimated price
- $110–550
- Website
- jetblue.com
Flights from Boston Logan Airport to Key West International Airport
- Ave. Duration
- 3h 58m
- When
- Every day
- Estimated price
- $130–650
- Website
- spirit.com
Flights from Boston Logan Airport to Key West International Airport via Fort Lauderdale
- Ave. Duration
- 8h 3m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $100–480
- Website
- united.com
Flights from Barnstable Municipal Airport to Key West International Airport via Chicago O'Hare
- Ave. Duration
- 7h 9m
- When
- Saturday
- Estimated price
- $270–1,200
- Website
- flybreeze.com
Flights from Theodore Francis Green State Airport to Key West International Airport via Orlando
- Ave. Duration
- 6h 26m
- When
- Monday and Friday
- Estimated price
- $300–440
Rome2Rio's guide to Amtrak Northeast Regional
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 4h 2m
- Frequency
- Every 3 hours
- Estimated price
- $30–300
- Website
- https://www.amtrak.com/home
- Schedules at
- https://www.amtrak.com/northeast-regional-train
- Coach
- $30–300
- Business Class
- $95–360
Rome2Rio's guide to Amtrak Acela
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 41m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $50–490
- First Class
- $200–750
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Ny Moynihan Train Hall At Penn Station to Miami Amtrak Station
- Ave. Duration
- 28h 29m
- Frequency
- Once daily
- Estimated price
- $160–430
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-617-222-3200
- Website
- mbta.com
Train from South Station to TF Green Airport
- Ave. Duration
- 1h 25m
- Frequency
- Every 4 hours
- Estimated price
- $6–16
- Website
- https://www.mbta.com
- Adult
- $6–16
- Phone
- +1 (508) 746-0378
- info@p-b.com
- Website
- p-b.com
Bus from Hyannis Transportation Center to Logan International Airport
- Ave. Duration
- 2h 15m
- Frequency
- Hourly
- Estimated price
- $28–40
- Website
- https://www.p-b.com
- One Way - Adult
- $28–40
- Phone
- 1-800-343-9999
- Website
- peterpanbus.com
Bus from Hyannis Transportation Center to Boston South Station
- Ave. Duration
- 1h 40m
- Frequency
- Every 4 hours
- Estimated price
- $10–40
- Website
- https://peterpanbus.com
- Adult
- $10–40
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Estimated price
- $21–30
- Website
- https://www.greyhound.com/
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
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