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How to get fromHyannis to Key Westby plane, bus, train, or car

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There are 4 ways to get from Hyannis to Key West by plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Barnstable Municipal Airport

    best
    1. Fly from Barnstable Municipal Airport (HYA) to Key West International Airport (EYW)plane plane HYA - EYW
    17h 38m
    $131–567

  2. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Stationbus bus
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Miami Amtrak Stationtrain train
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    5. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    42h 58m
    $477–1,700

  3. Drive 1,675.8 mi

    1. Drive from Hyannis to Key Westcar car 1,675.8 mi
    29h 53m
    $306–442

  4. Bus to Boston Logan Airport, fly

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Key West International Airport (EYW)plane plane BOS - EYW
    7h 18m
    $279–599

Hyannis to Key West by bus, train, taxi, and foot

Calendar7Weekly Services
Duration42h 58mAverage Duration
Ticket$477Cheapest Price
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Questions & Answers

What companies run services between Hyannis, MA, USA and Key West, FL, USA?

American Airlines, Cape Air, and JetBlue Airways fly from Barnstable Municipal Airport (HYA) to Key West International Airport (EYW) 5 times a day.

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