There are 7 ways to get from Hyannis to Key Largo by plane, shuttle, bus (Flixbus, Greyhound), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Barnstable Municipal Airport to Miami International Airport, shuttle
best- Fly from Barnstable Municipal Airport (HYA) to Miami International Airport (MIA)HYA - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
8h 41m$193–663Bus to Boston Logan Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle
cheapest- Take the bus from Hyannis Transportation Center to Logan International Airport
- Fly from Boston Logan Airport (BOS) to Fort Lauderdale–Hollywood International Airport (FLL)BOS - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FL
9h 23m$188–456Bus
- Take the bus from Hyannis Transportation Center to Boston South Buses
- Take the bus from Boston to New York Midtown
- Take the bus from New York Midtown to Baltimore Downtown Bus Station
- Take the bus from Baltimore Downtown Bus Station to Orlando Bus Station
- Take the bus from Orlando Bus Station to Miami Airport Station
- Take the bus from Miami Airport Station to Key Largo Bus Stop
38h 21m$228–398Bus, train
- Take the bus from Hyannis Transportation Center to Boston South Station
- Take the train from Boston to Ny Moynihan Train Hall At Penn Station
- Take the train from Ny Moynihan Train Hall At Penn Station to Hollywood Amtrak Station
- Take the bus from Miami Airport Station to Key Largo Bus Stop
38h 49m$236–1,510Drive 1,579.8 mi
- Drive from Hyannis to Key Largo1,579.8 mi
27h 20m$289–417Bus to Boston Logan Airport, fly to Miami International Airport, shuttle
- Take the bus from Hyannis Transportation Center to Logan International Airport
- Fly from Boston Logan Airport (BOS) to Miami International Airport (MIA)BOS - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
9h 5m$193–526Bus, train to Theodore Francis Green State Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle
- Take the bus from Hyannis Transportation Center to Boston South Station
- Take the train from Boston to Providence
- Fly from Theodore Francis Green State Airport (PVD) to Fort Lauderdale–Hollywood International Airport (FLL)PVD - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FL
10h 29m$317–1,578
Hyannis to Key Largo by bus
Questions & Answers
The cheapest way to get from Hyannis to Key Largo is to bus and fly and shuttle which costs $180 - $460 and takes 9h 23m.
The fastest way to get from Hyannis to Key Largo is to fly and shuttle which takes 8h 41m and costs $190 - $700.
No, there is no direct bus from Hyannis to Key Largo. However, there are services departing from Hyannis Transportation Center and arriving at Key Largo Bus Stop via Boston, New York Midtown, Baltimore Downtown Bus Station, Orlando Bus Station and Miami Airport Station. The journey, including transfers, takes approximately 38h 21m.
The distance between Hyannis and Key Largo is 1301 miles. The road distance is 1589 miles.
The best way to get from Hyannis to Key Largo without a car is to bus which takes 38h 21m and costs $220 - $400.
It takes approximately 8h 41m to get from Hyannis to Key Largo, including transfers.
Hyannis to Key Largo bus services, operated by Plymouth & Brockton, depart from Hyannis Transportation Center station.
Hyannis to Key Largo bus services, operated by Plymouth & Brockton, arrive at Boston South Buses station.
Yes, the driving distance between Hyannis to Key Largo is 1589 miles. It takes approximately 27h 20m to drive from Hyannis to Key Largo.
There are 304+ hotels available in Key Largo.
What companies run services between Hyannis, MA, USA and Key Largo, FL, USA?
You can take a bus from Hyannis Transportation Center to Key Largo Bus Stop via Boston, Bus Terminal South Station, Boston, New York Midtown, Baltimore Downtown Bus Station, Orlando Bus Station, and Miami Airport Station in around 38h 21m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- jetblue.com
Flights from Boston Logan Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 29m
- When
- Every day
- Estimated price
- $65–330
Flights from Boston Logan Airport to Fort Lauderdale–Hollywood International Airport via Charleston
- Ave. Duration
- 5h 23m
- When
- Tuesday
- Estimated price
- $70–330
Flights from Theodore Francis Green State Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 13m
- When
- Every day
- Estimated price
- $60–290
- Website
- southwest.com
Flights from Boston Logan Airport to Miami International Airport via Baltimore
- Ave. Duration
- 5h 18m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $90–440
Flights from Boston Logan Airport to Fort Lauderdale–Hollywood International Airport via Baltimore
- Ave. Duration
- 5h 15m
- When
- Monday, Tuesday, Wednesday, and Saturday
- Estimated price
- $70–330
Flights from Theodore Francis Green State Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 15m
- When
- Saturday
- Estimated price
- $60–290
Flights from Theodore Francis Green State Airport to Fort Lauderdale–Hollywood International Airport via Baltimore
- Ave. Duration
- 5h 25m
- When
- Every day
- Estimated price
- $60–300
- Website
- aa.com
Flights from Barnstable Municipal Airport to Miami International Airport via Philadelphia
- Ave. Duration
- 5h 21m
- When
- Every day
- Estimated price
- $110–550
Flights from Barnstable Municipal Airport to Miami International Airport via New York La Guardia
- Ave. Duration
- 5h 33m
- When
- Every day
- Estimated price
- $110–550
Flights from Barnstable Municipal Airport to Miami International Airport via Reagan Washington
- Ave. Duration
- 6h 2m
- When
- Every day
- Estimated price
- $110–550
Flights from Barnstable Municipal Airport to Miami International Airport via Chicago O'Hare
- Ave. Duration
- 8h 17m
- When
- Saturday
- Estimated price
- $160–700
Flights from Barnstable Municipal Airport to Miami International Airport via Boston Logan Airport
- Ave. Duration
- 6h 34m
- When
- Monday, Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- $110–550
Flights from Boston Logan Airport to Miami International Airport
- Ave. Duration
- 3h 43m
- When
- Every day
- Estimated price
- $90–430
- Website
- delta.com
Flights from Barnstable Municipal Airport to Miami International Airport via New York JFK
- Ave. Duration
- 6h 15m
- When
- Every day
- Estimated price
- $110–550
Flights from Boston Logan Airport to Miami International Airport
- Ave. Duration
- 3h 36m
- When
- Every day
- Estimated price
- $90–430
Flights from Boston Logan Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 30m
- When
- Every day
- Estimated price
- $65–330
- Website
- spirit.com
Flights from Boston Logan Airport to Miami International Airport
- Ave. Duration
- 3h 37m
- When
- Wednesday
- Estimated price
- $85–380
Flights from Boston Logan Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 29m
- When
- Every day
- Estimated price
- $60–280
Flights from Boston Logan Airport to Fort Lauderdale–Hollywood International Airport via Myrtle Beach
- Ave. Duration
- 5h 3m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $60–280
- Website
- flybreeze.com
Flights from Theodore Francis Green State Airport to Fort Lauderdale–Hollywood International Airport via Myrtle Beach
- Ave. Duration
- 5h 43m
- When
- Monday and Friday
- Estimated price
- $200–800
Rome2Rio's guide to Amtrak Northeast Regional
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 4h 2m
- Frequency
- Every 3 hours
- Estimated price
- $30–300
- Website
- https://www.amtrak.com/home.html
- Schedules at
- https://www.amtrak.com/northeast-regional-train
- Coach
- $30–300
- Business Class
- $95–360
Train from Boston to Providence
- Ave. Duration
- 39 min
- Frequency
- Every 3 hours
- Estimated price
- $6–210
- Website
- https://www.amtrak.com/home.html
- Schedules at
- https://www.amtrak.com/northeast-regional-train
- Coach
- $6–210
- Business Class
- $45–240
Rome2Rio's guide to Amtrak Acela
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 41m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $50–490
- First Class
- $200–750
Train from Boston to Providence
- Ave. Duration
- 34 min
- Frequency
- Every 4 hours
- Estimated price
- $10–600
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $10–450
- First Class
- $110–600
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Ny Moynihan Train Hall At Penn Station to Hollywood Amtrak Station
- Ave. Duration
- 27h 51m
- Frequency
- Once daily
- Estimated price
- $180–700
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-617-222-3200
- Website
- mbta.com
Train from Boston to Providence
- Ave. Duration
- 1h 10m
- Frequency
- Hourly
- Estimated price
- $5–14
- Website
- https://www.mbta.com
- Adult
- $5–14
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 15m
- Frequency
- 4 times a day
- Estimated price
- $80–110
- Website
- https://www.keysshuttle.com
Shuttle from Fort Lauderdale, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 45m
- Frequency
- 4 times a day
- Estimated price
- $100–140
- Website
- https://www.keysshuttle.com
- Phone
- +1 (508) 746-0378
- info@p-b.com
- Website
- p-b.com
Bus from Hyannis Transportation Center to Boston South Buses
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $27–35
- Website
- https://www.p-b.com
- One Way - Adult
- $27–35
Bus from Hyannis Transportation Center to Logan International Airport
- Ave. Duration
- 2h 15m
- Frequency
- Hourly
- Estimated price
- $28–40
- Website
- https://www.p-b.com
- One Way - Adult
- $28–40
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Boston to New York Midtown
- Ave. Duration
- 4h 20m
- Frequency
- Every 3 hours
- Estimated price
- $30–65
- Schedules at
- flixbus.com
Bus from New York Midtown to Baltimore Downtown Bus Station
- Ave. Duration
- 3h 30m
- Frequency
- Every 3 hours
- Estimated price
- $30–60
- Schedules at
- flixbus.com
Bus from Baltimore Downtown Bus Station to Orlando Bus Station
- Ave. Duration
- 17h 40m
- Frequency
- 5 times a week
- Estimated price
- $100–170
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to Miami Airport Station
- Ave. Duration
- 4h 50m
- Frequency
- Hourly
- Estimated price
- $28–50
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Orlando Bus Station to Miami Airport Station
- Ave. Duration
- 6h 20m
- Frequency
- 4 times a day
- Estimated price
- $28–45
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Key Largo Bus Stop
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- $13–18
- Website
- https://www.greyhound.com/
- Phone
- 1-800-343-9999
- Website
- peterpanbus.com
Bus from Hyannis Transportation Center to Boston South Station
- Ave. Duration
- 1h 40m
- Frequency
- Every 4 hours
- Estimated price
- $10–40
- Website
- https://peterpanbus.com
- Adult
- $10–40
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