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How to get fromHyannis to Ithacaby bus (Flixbus), bus, train, car or plane

Find Transport to Ithaca

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There are 8 ways to get from Hyannis to Ithaca by bus (Flixbus), bus, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Hyannis Transportation Center to Boston South Stationbus bus Hyannis
    2. Take the bus from Boston to Ithacabus bus FlixBus 2691
    10h 24m
    $55–116

  2. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the train from Boston to Utica Amtrak Stationtrain train
    3. Take the bus from Utica Bus Stop to Ithacabus bus
    13h 54m
    $105–208

  3. Drive 390 mi

    1. Drive from Hyannis to Ithacacar car 390 mi
    7h 20m
    $72–103

  4. Fly Barnstable Municipal Airport to Syracuse Hancock International Airport, bus

    1. Fly from Barnstable Municipal Airport (HYA) to Syracuse Hancock International Airport (SYR)plane plane HYA - SYR
    2. Take the bus from Syracuse Bus Station to Ithacabus bus
    6h 47m
    $145–933

  5. Bus to Boston Logan Airport, fly to Rochester, bus

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane plane BOS - ROC
    3. Take the bus from Rochester to Ithacabus bus
    7h 51m
    $277–865

  6. Bus to Boston Logan Airport, fly to Syracuse Hancock International Airport, bus

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Syracuse Hancock International Airport (SYR)plane plane BOS - SYR
    3. Take the bus from Syracuse Bus Station to Ithacabus bus
    7h 52m
    $118–676

  7. Fly Barnstable Municipal Airport to Ithaca Tompkins Regional Airport

    1. Fly from Barnstable Municipal Airport (HYA) to Ithaca Tompkins Regional Airport (ITH)plane plane HYA - ITH
    4h 51m
    $70–470

  8. Bus to Provincetown Municipal Airport, fly to Syracuse Hancock International Airport, bus

    1. Take the bus from Theophilus F. Smith Road to Race Point Beachbus bus
    2. Fly from Provincetown Municipal Airport (PVC) to Syracuse Hancock International Airport (SYR)plane plane PVC - SYR
    3. Take the bus from Syracuse Bus Station to Ithacabus bus
    13h 41m
    $101–646

Hyannis to Ithaca by bus

Calendar5Weekly Buses
Duration10h 24mAverage Duration
Ticket$55Cheapest Price
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Questions & Answers

What companies run services between Hyannis, MA, USA and Ithaca, NY, USA?

You can take a bus from Hyannis Transportation Center to Ithaca via Boston South Station and Boston in around 10h 24m. Alternatively, Cape Air, Delta, and JetBlue Airways fly from Barnstable Municipal Airport (HYA) to Ithaca Tompkins Regional Airport (ITH) 6 times a week.

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