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How to get fromHyannis to Ithacaby bus (Flixbus), bus, train, car or plane

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There are 10 ways to get from Hyannis to Ithaca by bus (Flixbus), bus, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Hyannis Transportation Center to Boston South BusesbusHyannis - South Shore to Logan Airport
    2. Take the bus from Boston to IthacabusFlixBus 2691
    10h 34m
    $82–185

  2. Bus, train via New York

    cheapest
    1. Take the bus from Hyannis Transportation Center to Boston South Stationbus
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain
    3. Take the bus from New York, NY to Ithaca, NYbus
    11h 50m
    $60–866

  3. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Stationbus
    2. Take the train from Boston to Syracuse Regional Transportation Centertrain
    3. Take the bus from Syracuse Bus Station to Ithacabus
    13h 45m
    $164–466

  4. Drive 390 mi

    1. Drive from Hyannis to Ithacacar390 mi
    7h 19m
    $72–103

  5. Fly Barnstable Municipal Airport to Syracuse Hancock International Airport, bus

    1. Fly from Barnstable Municipal Airport (HYA) to Syracuse Hancock International Airport (SYR)planeHYA - SYR
    2. Take the bus from Syracuse Airport, NY to Ithaca, NYbus
    7h 19m
    $123–758

  6. Bus, train via Utica

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus
    2. Take the train from Boston to Utica Amtrak Stationtrain
    3. Take the bus from Utica, NY to Ithaca, NYbus
    14h 30m
    $187–485

  7. Bus to Boston Logan Airport, fly to Syracuse Hancock International Airport, bus

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus
    2. Fly from Boston Logan Airport (BOS) to Syracuse Hancock International Airport (SYR)planeBOS - SYR
    3. Take the bus from Syracuse Airport, NY to Ithaca, NYbus
    7h 22m
    $118–641

  8. Bus to Boston Logan Airport, fly to Rochester, bus

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus
    2. Fly from Boston Logan Airport (BOS) to Rochester (ROC)planeBOS - ROC
    3. Take the bus from Rochester, NY to Ithaca, NYbus
    8h 24m
    $208–536

  9. Bus to Provincetown Municipal Airport, fly to Syracuse Hancock International Airport, bus

    1. Take the bus from Hyannis Transportation Center to Provincetownbus
    2. Fly from Provincetown Municipal Airport (PVC) to Syracuse Hancock International Airport (SYR)planePVC - SYR
    3. Take the bus from Syracuse Airport, NY to Ithaca, NYbus
    11h 1m
    $120–740

  10. Fly Barnstable Municipal Airport to Ithaca Tompkins Regional Airport

    1. Fly from Barnstable Municipal Airport (HYA) to Ithaca Tompkins Regional Airport (ITH)planeHYA - ITH
    6h 2m
    $63–423

Hyannis to Ithaca by bus

Calendar10Weekly Buses
Duration10h 34mAverage Duration
Ticket$82Cheapest Price
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Questions & Answers

What companies run services between Hyannis, MA, USA and Ithaca, NY, USA?

You can take a bus from Hyannis Transportation Center to Ithaca via Boston, Bus Terminal South Station and Boston in around 10h 34m. Alternatively, Cape Air, Delta, and two other airlines fly from Barnstable Municipal Airport (HYA) to Ithaca Tompkins Regional Airport (ITH) twice daily.

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