There are 9 ways to get from Hyannis to Ithaca by bus (Flixbus), bus, train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Hyannis Transportation Center to Boston South Busesbus Hyannis - South Shore to Logan Airport
- Take the bus from Boston to Ithacabus FlixBus 2691
10h 34m$82–125Fly Barnstable Municipal Airport to Ithaca Tompkins Regional Airport
cheapest- Fly from Barnstable Municipal Airport (HYA) to Ithaca Tompkins Regional Airport (ITH)plane HYA - ITH
8h 24m$60–380Bus, train
- Take the bus from Hyannis Transportation Center to Boston South Busesbus
- Take the train from Boston to Utica Amtrak Stationtrain
- Take the bus from Utica Bus Stop to Ithacabus
13h 54m$118–242Drive 390 mi
- Drive from Hyannis to Ithacacar 390 mi
7h 21m$72–103Fly Barnstable Municipal Airport to Syracuse Hancock International Airport, bus
- Fly from Barnstable Municipal Airport (HYA) to Syracuse Hancock International Airport (SYR)plane HYA - SYR
- Take the bus from Syracuse Bus Station to Ithacabus
6h 49m$118–724Bus via New Haven
- Take the bus from Hyannis to Providencebus
- Take the bus from Providence to New Havenbus
- Take the bus from New Haven, CT - Union Station to Ithaca, NY - West Ave across from Bakers Flagpolebus
11h 40m$126–309Bus to Boston Logan Airport, fly to Rochester, bus
- Take the bus from Hyannis Transportation Center to Logan International Airportbus
- Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane BOS - ROC
- Take the bus from Rochester to Ithacabus
7h 43m$167–765Bus to Provincetown Municipal Airport, fly to Syracuse Hancock International Airport, bus
- Take the bus from Hyannis to Provincetownbus
- Fly from Provincetown Municipal Airport (PVC) to Syracuse Hancock International Airport (SYR)plane PVC - SYR
- Take the bus from Syracuse Bus Station to Ithacabus
9h 47m$168–982Bus to Boston Logan Airport, fly to Syracuse Hancock International Airport, bus
- Take the bus from Hyannis Transportation Center to Logan International Airportbus
- Fly from Boston Logan Airport (BOS) to Syracuse Hancock International Airport (SYR)plane BOS - SYR
- Take the bus from Syracuse Bus Station to Ithacabus
7h 50m$130–728
Hyannis to Ithaca by bus
Questions & Answers
The cheapest way to get from Hyannis to Ithaca is to drive which costs $70 - $110 and takes 7h 21m.
The fastest way to get from Hyannis to Ithaca is to fly and bus which takes 6h 49m and costs $110 - $750.
No, there is no direct bus from Hyannis to Ithaca. However, there are services departing from Hyannis Transportation Center and arriving at Ithaca via Boston. The journey, including transfers, takes approximately 10h 34m.
The distance between Hyannis and Ithaca is 455 miles. The road distance is 392.3 miles.
The best way to get from Hyannis to Ithaca without a car is to bus which takes 10h 34m and costs $80 - $130.
It takes approximately 10h 34m to get from Hyannis to Ithaca, including transfers.
Hyannis to Ithaca bus services, operated by Plymouth & Brockton, depart from Hyannis Transportation Center station.
The best way to get from Hyannis to Ithaca is to bus which takes 10h 34m and costs $80 - $130. Alternatively, you can fly, which costs $60 - $380 and takes 8h 24m.
Hyannis to Ithaca bus services, operated by Plymouth & Brockton, arrive at Boston South Buses station.
Yes, the driving distance between Hyannis to Ithaca is 392 miles. It takes approximately 7h 21m to drive from Hyannis to Ithaca.
What companies run services between Hyannis, MA, USA and Ithaca, NY, USA?
You can take a bus from Hyannis Transportation Center to Ithaca via Boston, South Station and Boston in around 10h 34m. Alternatively, Cape Air, JetBlue Airways, and Delta fly from Barnstable Municipal Airport (HYA) to Ithaca Tompkins Regional Airport (ITH) twice daily.
- Website
- delta.com
Flights from Boston Logan Airport to Rochester via New York La Guardia
- Ave. Duration
- 3h 48m
- When
- Monday to Friday
- Estimated price
- $110–700
Flights from Provincetown Municipal Airport to Syracuse Hancock International Airport via Boston Logan Airport, New York La Guardia
- Ave. Duration
- 6h 8m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–950
Flights from Barnstable Municipal Airport to Ithaca Tompkins Regional Airport via Boston Logan Airport, New York JFK
- Ave. Duration
- 8h 45m
- When
- Every day
- Estimated price
- $60–390
Flights from Barnstable Municipal Airport to Ithaca Tompkins Regional Airport via Martha's Vineyard, New York JFK
- Ave. Duration
- 14h 54m
- When
- Sunday
- Estimated price
- $60–380
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Utica Amtrak Station
- Ave. Duration
- 7h 55m
- Frequency
- Once daily
- Estimated price
- $75–180
- Website
- Amtrak
- Phone
- +1 (508) 746-0378
- info@p-b.com
- Website
- Plymouth & Brockton
Bus from Hyannis Transportation Center to Boston South Buses
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $27–35
- Website
- Plymouth & Brockton
- One Way - Adult
- $27–35
Bus from Hyannis Transportation Center to Boston South Buses
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $27–35
- Website
- Plymouth & Brockton
- One Way - Adult
- $27–35
Bus from Hyannis Transportation Center to Logan International Airport
- Ave. Duration
- 2h 15m
- Frequency
- Every 30 minutes
- Estimated price
- $28–40
- Website
- Plymouth & Brockton
- One Way - Adult
- $28–40
Bus from Hyannis Transportation Center to Logan International Airport
- Ave. Duration
- 2h 15m
- Frequency
- Every 30 minutes
- Estimated price
- $28–40
- Website
- Plymouth & Brockton
- One Way - Adult
- $28–40
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Book your Hyannis to Ithaca bus tickets online with Omio.
There are 86+ hotels available in Ithaca.




