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How to get fromHyannis to Indianapolisby plane, bus (Greyhound, Flixbus), bus, train, car or bus (Greyhound)

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There are 7 ways to get from Hyannis to Indianapolis by plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Barnstable Municipal Airport

    best
    1. Fly from Barnstable Municipal Airport (HYA) to Indianapolis (IND)plane plane HYA - IND
    6h 1m
    $92–478
  2. Bus via Boston

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to Newark Penn Stationbus bus
    3. Take the bus from Newark Penn Station to Indianapolisbus bus
    24h 10m
    $157–325
  3. Bus, train via Toledo

    1. Take the bus from Hyannis Transportation Center to Boston South Stationbus bus
    2. Take the train from Boston to Toledotrain train
    3. Take the bus from Toledo to Indianapolis, INbus bus
    25h 8m
    $181–901
  4. Drive 944.7 mi

    1. Drive from Hyannis to Indianapoliscar car 944.7 mi
    17h 20m
    $173–249
  5. Bus to Boston Logan Airport, fly

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Indianapolis (IND)plane plane BOS - IND
    6h 48m
    $150–408
  6. Bus

    1. Take the bus from Hyannis Transportation Center to Providence Bus Terminalbus bus
    2. Take the bus from Peter Pan Bus Terminal to Port Authority Bus Terminalbus bus
    3. Take the bus from Port Authority Bus Terminal to Indianapolis Union Stationbus bus
    25h 5m
    $127–363
  7. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Stationbus bus
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Indianapolistrain train
    29h 56m
    $170–1,436

Hyannis to Indianapolis by bus

Calendar7Weekly Buses
Duration24h 10mAverage Duration
Ticket$157Cheapest Price
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Questions & Answers

What companies run services between Hyannis, MA, USA and Indianapolis, IN, USA?

American Airlines, Cape Air, and Allegiant Air fly from Barnstable Municipal Airport (HYA) to Indianapolis (IND) 5 times a day. Alternatively, you can take a bus from Hyannis Transportation Center to Indianapolis via Boston, Bus Terminal South Station, Boston, and Newark Penn Station in around 24h 10m.

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