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How to get fromHouston to St. Louisby plane, bus, train, bus (Flixbus, Greyhound), car, or bus (Greyhound)

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There are 6 ways to get from Houston to St. Louis by plane, bus, train, bus (Flixbus, Greyhound), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from William P. Hobby Airport

    best
    1. Fly from William P. Hobby Airport (HOU) to Lambert–St. Louis International Airport (STL)plane plane HOU - STL
    4h 9m
    $174–904

  2. Line 102 bus to George Bush Intercontinental Airport, fly

    cheapest
    1. Take the bus from Travis St @ Texas Ave to Bush IAH Terminal Cbus bus
    2. Fly from George Bush Intercontinental Airport (IAH) to Lambert–St. Louis International Airport (STL)plane plane IAH - STL
    4h 43m
    $126–657

  3. Bus, train (Amtrak)

    1. Take the bus from Houston to Longviewbus bus Amtrak Thruway Connecting Service
    2. Take the train from Longview to St. Louistrain train Texas Eagle
    18h 47m
    $262–483

  4. Bus

    1. Take the bus from Downtown Houston to Memphis Bus Stationbus bus FlixBus N2211
    2. Take the bus from Memphis Bus Station to St Louis Bus Stationbus bus FlixBus 2510
    20h 15m
    $157–277

  5. Drive 774.6 mi

    1. Drive from Houston to St. Louiscar car 774.6 mi
    14h 12m
    $142–205

  6. Bus via Baton Rouge (Greyhound)

    1. Take the bus from Houston Bus Station to Baton Rouge Bus Stationbus bus Greyhound US0602 / ...
    2. Take the bus from Baton Rouge Bus Station to St Louis Bus Stationbus bus Greyhound US1173
    24h 13m
    $161–307

Houston to St. Louis by bus and train (Amtrak)

Calendar7Weekly Services
Duration18h 47mAverage Duration
Ticket$262Cheapest Price
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Questions & Answers

Map of how to get from Houston to St. Louis.ExpandLaunch map view
  • Distance: 711.2 mi
  • Duration: 4h 9m

What companies run services between Houston, TX, USA and St. Louis, MO, USA?

Southwest Airlines flies from William P. Hobby Airport (HOU) to Lambert–St. Louis International Airport (STL) every 3 hours. Alternatively, you can take a bus from Downtown Houston to St Louis Bus Station via Memphis Bus Station in around 20h 15m.

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