There are 9 ways to get from Houston to Sikeston by plane, taxi, bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly George Bush Intercontinental Airport to Barkley Regional Airport, taxi
best- Fly from George Bush Intercontinental Airport (IAH) to Barkley Regional Airport (PAH)IAH - PAH
- Take the taxi from Barkley Regional Airport (PAH) to Sikeston
4h 55m$208–634Drive 672.4 mi
cheapest- Drive from Houston to Sikeston672.4 mi
12h 8m$123–178Bus, train, taxi (Amtrak)
- Take the bus from Houston to Longview
- Take the train from Longview to Poplar Bluff Station
- Take the taxi from Poplar Bluff Station to Sikeston
15hBus
- Take the bus from Houston - Travis St @ Dallas St to 593 S Lamar St DallasHouston
- Take the bus from Dallas to Flying J - MatthewsMilwaukee
17h 24m$154–335Fly William P. Hobby Airport to Lambert–St. Louis International Airport, bus, taxi
- Fly from William P. Hobby Airport (HOU) to Lambert–St. Louis International Airport (STL)HOU - STL
- Take the bus from St Louis Bus Station to Cape Girardeau
- Take the taxi from Cape Girardeau to Sikeston
8h 8m$268–1,074Fly George Bush Intercontinental Airport to Lambert–St. Louis International Airport, bus, taxi
- Fly from George Bush Intercontinental Airport (IAH) to Lambert–St. Louis International Airport (STL)IAH - STL
- Take the bus from St Louis Bus Station to Cape Girardeau
- Take the taxi from Cape Girardeau to Sikeston
8h 20m$328–615Fly William P. Hobby Airport to Memphis, bus
- Fly from William P. Hobby Airport (HOU) to Memphis (MEM)HOU - MEM
- Take the bus from Tornado Bus Co - West Memphis to Flying J - Matthews
8h 35m$219–994Fly George Bush Intercontinental Airport to Memphis, bus
- Fly from George Bush Intercontinental Airport (IAH) to Memphis (MEM)IAH - MEM
- Take the bus from Tornado Bus Co - West Memphis to Flying J - Matthews
8h 44m$239–545Bus, taxi
- Take the bus from Downtown Houston to Memphis Bus Station
- Take the bus from Memphis Bus Station to Cape Girardeau
- Take the taxi from Cape Girardeau to Sikeston
18h 19m$189–332
George Bush Intercontinental Airport (IAH) to Barkley Regional Airport (PAH) flights
Questions & Answers
The cheapest way to get from Houston to Sikeston is to drive which costs $120 - $180 and takes 12h 8m.
The fastest way to get from Houston to Sikeston is to fly and taxi which takes 4h 55m and costs $200 - $650.
The distance between Houston and Sikeston is 701 miles. The road distance is 676.3 miles.
The best way to get from Houston to Sikeston without a car is to bus and train and taxi which takes 15h and costs .
It takes approximately 4h 55m to get from Houston to Sikeston, including transfers.
Yes, the driving distance between Houston to Sikeston is 676 miles. It takes approximately 12h 8m to drive from Houston to Sikeston.
There are 13+ hotels available in Sikeston.
What companies run services between Houston, TX, USA and Sikeston, MO, USA?
You can take a bus from Houston - Travis St @ Dallas St to Sikeston via 593 S Lamar St Dallas, Lamar @ Ceremonial - N - Ns, Ih 30 @ St Francis - E - Mb, Dallas, and Flying J - Matthews in around 17h 24m.
- Website
- southwest.com
Flights from William P. Hobby Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 59m
- When
- Every day
- Estimated price
- $170–950
Flights from William P. Hobby Airport to Lambert–St. Louis International Airport via Dallas
- Ave. Duration
- 3h 50m
- When
- Monday, Tuesday, Friday, Saturday, and Sunday
- Estimated price
- $180–1,000
Flights from William P. Hobby Airport to Lambert–St. Louis International Airport via New Orleans
- Ave. Duration
- 3h 50m
- When
- Wednesday and Thursday
- Estimated price
- $200–1,100
Flights from William P. Hobby Airport to Lambert–St. Louis International Airport via Austin
- Ave. Duration
- 4h
- When
- Monday, Tuesday, Friday, and Sunday
- Estimated price
- $200–1,000
Flights from William P. Hobby Airport to Memphis
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $130–800
Flights from William P. Hobby Airport to Memphis via Dallas
- Ave. Duration
- 3h 41m
- When
- Every day
- Estimated price
- $160–850
- Website
- aa.com
Flights from George Bush Intercontinental Airport to Lambert–St. Louis International Airport via Dallas/Ft.Worth
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $100–550
Flights from George Bush Intercontinental Airport to Memphis via Dallas/Ft.Worth
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $90–490
- Website
- united.com
Flights from George Bush Intercontinental Airport to Barkley Regional Airport
- Ave. Duration
- 1h 50m
- When
- Tuesday to Saturday
- Estimated price
- $85–480
Flights from George Bush Intercontinental Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 5m
- When
- Every day
- Estimated price
- $95–550
Flights from George Bush Intercontinental Airport to Memphis
- Ave. Duration
- 1h 39m
- When
- Every day
- Estimated price
- $75–440
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Longview to Poplar Bluff Station
- Ave. Duration
- 8h 31m
- Frequency
- Once daily
- Estimated price
- $40–150
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $40–110
- Coach Seat short notice purchase
- $50–150
- Business - advance purchase
- $70–320
- Business Class
- $120–350
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Houston to Longview
- Ave. Duration
- 4h 35m
- Frequency
- Once daily
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Houston - Travis St @ Dallas St to 593 S Lamar St Dallas
- Ave. Duration
- 4h 40m
- Frequency
- 3 times a day
- Estimated price
- $27–85
- Website
- https://www.redcoachusa.com
- Web
- $27–85
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- tornadobus.com
Bus from Dallas to Flying J - Matthews
- Ave. Duration
- 10h 45m
- Frequency
- Once daily
- Estimated price
- $100–220
- Schedules at
- tornadobus.com
- Adults 11-59
- $100–220
Bus from Tornado Bus Co - West Memphis to Flying J - Matthews
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $45–140
- Schedules at
- tornadobus.com
- Adults 11-59
- $45–140
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $22–28
- Website
- https://www.greyhound.com/
Bus from Memphis Bus Station to Cape Girardeau
- Ave. Duration
- 3h 15m
- Frequency
- Once daily
- Estimated price
- $35–75
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Downtown Houston to Memphis Bus Station
- Ave. Duration
- 13h 30m
- Frequency
- 5 times a week
- Estimated price
- $80–170
- Schedules at
- flixbus.com
- Ave. Duration
- 46 min
- Estimated price
- $70–150
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide















