There are 9 ways to get from Houston to Sikeston by plane, car, bus, train, taxi, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly George Bush Intercontinental Airport to Barkley Regional Airport, drive
best- Fly from George Bush Intercontinental Airport (IAH) to Barkley Regional Airport (PAH)plane IAH - PAH
- Drive from Barkley Regional Airport (PAH) to Sikestoncar
4h 56m$83–409Bus, train, taxi (Amtrak)
- Take the bus from Houston to Longviewbus
- Take the train from Longview to Poplar Bluff Stationtrain
- Take the taxi from Poplar Bluff Station to Sikestontaxi
15hBus
- Take the bus from Downtown Houston to Downtown Dallas / Deep Ellumbus FlixBus 2240 / ...
- Take the bus from Dallas to Flying J - Matthewsbus Milwaukee
17h 10m$188–236Drive 672.5 mi
- Drive from Houston to Sikestoncar 672.5 mi
12h 5m$123–178Fly William P. Hobby Airport to Lambert–St. Louis International Airport, bus, taxi
- Fly from William P. Hobby Airport (HOU) to Lambert–St. Louis International Airport (STL)plane HOU - STL
- Take the bus from St Louis Bus Station to Cape Girardeaubus
- Take the taxi from Cape Girardeau to Sikestontaxi
7h 49m$242–903Fly William P. Hobby Airport to Memphis, bus
- Fly from William P. Hobby Airport (HOU) to Memphis (MEM)plane HOU - MEM
- Take the bus from Tornado Bus Co - West Memphis to Flying J - Matthewsbus
8h 5m$237–1,117Fly George Bush Intercontinental Airport to Lambert–St. Louis International Airport, bus, taxi
- Fly from George Bush Intercontinental Airport (IAH) to Lambert–St. Louis International Airport (STL)plane IAH - STL
- Take the bus from St Louis Bus Station to Cape Girardeaubus
- Take the taxi from Cape Girardeau to Sikestontaxi
8h 26m$404–1,106Bus via Dallas
- Take the bus from Houston, TX - 808 Jefferson St to Dallas, TX - 1376 Marilla Stbus Houston
- Take the bus from Dallas to Flying J - Matthewsbus Milwaukee
17h 31m$214–266Bus, taxi
- Take the bus from Houston Bus Station to Baton Rouge Bus Stationbus
- Take the bus from Baton Rouge Bus Station to Cape Girardeaubus
- Take the taxi from Cape Girardeau to Sikestontaxi
22h 48m$241–362
George Bush Intercontinental Airport (IAH) to Barkley Regional Airport (PAH) flights
Comparing Your Travel Options
The cheapest way to get from Houston to Sikeston is to drive which costs $120 - $180 and takes 12h 5m.
The fastest way to get from Houston to Sikeston is to fly and drive which takes 4h 56m and costs $80 - $410.
No, there is no direct bus from Houston to Sikeston. However, there are services departing from Downtown Houston and arriving at Flying J - Matthews via Gaston @ Good Latimer - N - Ns and Dallas. The journey, including transfers, takes approximately 17h 10m.
The distance between Houston and Sikeston is 701 miles. The road distance is 676.4 miles.
The best way to get from Houston to Sikeston without a car is to bus and train and taxi which takes 15h and costs .
It takes approximately 4h 56m to get from Houston to Sikeston, including transfers.
Houston to Sikeston bus services, operated by Flixbus USA, depart from Downtown Houston station.
Houston to Sikeston bus services, operated by Flixbus USA, arrive at Downtown Dallas / Deep Ellum station.
Yes, the driving distance between Houston to Sikeston is 676 miles. It takes approximately 12h 5m to drive from Houston to Sikeston.
There are 13+ hotels available in Sikeston.
What companies run services between Houston, TX, USA and Sikeston, MO, USA?
You can take a bus from Downtown Houston to Sikeston via Downtown Dallas / Deep Ellum, Gaston @ Good Latimer - N - Ns, Samuell @ Cinnabar - E - Ns, Dallas, and Flying J - Matthews in around 17h 10m.
- Website
- southwest.com
Flights from William P. Hobby Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- $130–750
Flights from William P. Hobby Airport to Lambert–St. Louis International Airport via Austin
- Ave. Duration
- 3h 45m
- When
- Tuesday and Wednesday
- Estimated price
- $150–800
Flights from William P. Hobby Airport to Lambert–St. Louis International Airport via Kansas City
- Ave. Duration
- 4h
- When
- Monday, Thursday, and Friday
- Estimated price
- $160–850
Flights from William P. Hobby Airport to Lambert–St. Louis International Airport via New Orleans
- Ave. Duration
- 4h 5m
- When
- Sunday
- Estimated price
- $160–850
Flights from William P. Hobby Airport to Memphis
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $160–1,000
Flights from William P. Hobby Airport to Memphis via Dallas
- Ave. Duration
- 3h 42m
- When
- Sunday, Monday, Thursday, and Friday
- Estimated price
- $190–1,100
Flights from William P. Hobby Airport to Memphis via Nashville
- Ave. Duration
- 4h
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $220–1,200
- Website
- aa.com
Flights from George Bush Intercontinental Airport to Lambert–St. Louis International Airport via Dallas/Ft.Worth
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- $100–600
- Website
- united.com
Flights from George Bush Intercontinental Airport to Barkley Regional Airport
- Ave. Duration
- 1h 51m
- When
- Every day
- Estimated price
- $70–390
Flights from George Bush Intercontinental Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 12m
- When
- Every day
- Estimated price
- $95–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Longview to Poplar Bluff Station
- Ave. Duration
- 8h 31m
- Frequency
- Once daily
- Estimated price
- $220–350
- Website
- Amtrak
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Houston to Longview
- Ave. Duration
- 4h 35m
- Frequency
- Once daily
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Downtown Houston to Downtown Dallas / Deep Ellum
- Ave. Duration
- 4h 30m
- Frequency
- 5 times a day
- Estimated price
- $35–55
- Schedules at
- Flixbus USA
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- Tornado Bus Company
Bus from Dallas to Flying J - Matthews
- Ave. Duration
- 10h 45m
- Frequency
- Once daily
- Estimated price
- $120–140
- Schedules at
- Tornado Bus Company
- Adult
- $120–140
Bus from Tornado Bus Co - West Memphis to Flying J - Matthews
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $26–50
- Schedules at
- Tornado Bus Company
- Adult
- $26–50
Bus from Dallas to Flying J - Matthews
- Ave. Duration
- 10h 45m
- Frequency
- Once daily
- Estimated price
- $120–140
- Schedules at
- Tornado Bus Company
- Adult
- $120–140
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $18–29
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $18–29
- Website
- Greyhound
Bus from Houston Bus Station to Baton Rouge Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- 5 times a day
- Estimated price
- $40–70
- Website
- Greyhound
Bus from Baton Rouge Bus Station to Cape Girardeau
- Ave. Duration
- 14h 55m
- Frequency
- Once daily
- Estimated price
- $110–170
- Website
- Greyhound
- Phone
- +1 877 733 0724
- Website
- RedCoach
Bus from Houston, TX - 808 Jefferson St to Dallas, TX - 1376 Marilla St
- Ave. Duration
- 4h
- Frequency
- 3 times a day
- Estimated price
- $55–80
- Website
- RedCoach
- Ave. Duration
- 40 min
- Estimated price
- $90–160
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
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