There are 8 ways to get from Houston to Murphysboro by plane, car, bus (Flixbus), train (Amtrak), bus, or bus (Greyhound, Amtrak, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly George Bush Intercontinental Airport to Barkley Regional Airport, drive
best- Fly from George Bush Intercontinental Airport (IAH) to Barkley Regional Airport (PAH)plane IAH - PAH
- Drive from Barkley Regional Airport (PAH) to Murphysborocar
5h 13m$116–674Bus
- Take the bus from Downtown Houston to Downtown Dallas / Deep Ellumbus FlixBus 2240 / ...
- Take the bus from Tornado Bus Co - Dallas I-30 to Marathon Gas Station - Marionbus Querétaro / ...
17h 25m$195–357Train (Amtrak)
- Take the train from Houston to New Orleans Union Passenger Terminaltrain Sunset Limited
- Take the train from New Orleans Union Passenger Terminal to Carbondaletrain City of New Orleans
24h 6m$291–623Drive 754.5 mi
- Drive from Houston to Murphysborocar 754.5 mi
13h 23m$138–199Fly William P. Hobby Airport to Lambert–St. Louis International Airport, bus
- Fly from William P. Hobby Airport (HOU) to Lambert–St. Louis International Airport (STL)plane HOU - STL
- Take the bus from St. Louis to Carbondalebus
7h 24m$235–1,282Fly George Bush Intercontinental Airport to Lambert–St. Louis International Airport, bus
- Fly from George Bush Intercontinental Airport (IAH) to Lambert–St. Louis International Airport (STL)plane IAH - STL
- Take the bus from St. Louis to Carbondalebus
7h 52m$157–785Fly William P. Hobby Airport to Nashville, bus
- Fly from William P. Hobby Airport (HOU) to Nashville (BNA)plane HOU - BNA
- Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus
9h 10m$148–726Bus via St. Louis
- Take the bus from Houston Bus Station to Dallas Bus Stationbus
- Take the bus from Dallas Bus Station to St Louis Bus Stationbus
- Take the bus from St. Louis to Carbondalebus
26h 3m$212–435
George Bush Intercontinental Airport (IAH) to Barkley Regional Airport (PAH) flights
Questions & Answers
The cheapest way to get from Houston to Murphysboro is to drive which costs $130 - $200 and takes 13h 23m.
The fastest way to get from Houston to Murphysboro is to fly and drive which takes 5h 13m and costs $110 - $700.
The distance between Houston and Murphysboro is 722 miles. The road distance is 758.9 miles.
The best way to get from Houston to Murphysboro without a car is to bus which takes 17h 25m and costs $190 - $360.
It takes approximately 5h 13m to get from Houston to Murphysboro, including transfers.
The best way to get from Houston to Murphysboro is to bus which takes 17h 25m and costs $190 - $360. Alternatively, you can train, which costs $290 - $650 and takes 24h 6m.
Yes, the driving distance between Houston to Murphysboro is 759 miles. It takes approximately 13h 23m to drive from Houston to Murphysboro.
There are 117+ hotels available in Murphysboro.
What companies run services between Houston, TX, USA and Murphysboro, IL, USA?
You can take a bus from Downtown Houston to Murphysboro via Downtown Dallas / Deep Ellum, Gaston @ Good Latimer - N - Ns, Samuell @ Cinnabar - E - Ns, Tornado Bus Co - Dallas I-30, and Marathon Gas Station - Marion in around 17h 25m. Alternatively, you can take a train from Houston to Murphysboro via New Orleans Union Passenger Terminal and Carbondale in around 24h 6m.
- Website
- southwest.com
Flights from William P. Hobby Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 1m
- When
- Every day
- Estimated price
- $200–1,200
Flights from William P. Hobby Airport to Lambert–St. Louis International Airport via Dallas
- Ave. Duration
- 3h 58m
- When
- Every day
- Estimated price
- $220–1,200
Flights from William P. Hobby Airport to Lambert–St. Louis International Airport via Nashville
- Ave. Duration
- 4h 10m
- When
- Saturday
- Estimated price
- $250–1,300
Flights from William P. Hobby Airport to Lambert–St. Louis International Airport via San Antonio
- Ave. Duration
- 4h 10m
- When
- Sunday
- Estimated price
- $260–1,400
Flights from William P. Hobby Airport to Nashville
- Ave. Duration
- 1h 56m
- When
- Every day
- Estimated price
- $100–650
Flights from William P. Hobby Airport to Nashville via Jackson/Vicksburg
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- $110–650
Flights from William P. Hobby Airport to Nashville via New Orleans
- Ave. Duration
- 3h 47m
- When
- Tuesday, Wednesday, and Sunday
- Estimated price
- $120–650
Flights from William P. Hobby Airport to Nashville via Dallas
- Ave. Duration
- 3h 56m
- When
- Monday to Friday
- Estimated price
- $120–700
- Website
- aa.com
Flights from George Bush Intercontinental Airport to Lambert–St. Louis International Airport via Dallas/Ft.Worth
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $130–750
- Website
- united.com
Flights from George Bush Intercontinental Airport to Barkley Regional Airport
- Ave. Duration
- 1h 52m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–650
Flights from George Bush Intercontinental Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 2h 7m
- When
- Every day
- Estimated price
- $120–700
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Houston to New Orleans Union Passenger Terminal
- Ave. Duration
- 9h 30m
- Frequency
- 3 times a week
- Estimated price
- $100–220
- Website
- https://www.amtrak.com/home.html
Train from New Orleans Union Passenger Terminal to Carbondale
- Ave. Duration
- 13h 26m
- Frequency
- Once daily
- Estimated price
- $170–380
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Downtown Houston to Downtown Dallas / Deep Ellum
- Ave. Duration
- 4h 25m
- Frequency
- Every 4 hours
- Estimated price
- $30–55
- Schedules at
- flixbus.com
Bus from St. Louis to Carbondale
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $12–22
- Schedules at
- flixbus.com
Bus from Nashville Bus Station to Carbondale Intermodal Station
- Ave. Duration
- 3h 50m
- Frequency
- Once daily
- Estimated price
- $26–50
- Schedules at
- flixbus.com
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- tornadobus.com
Bus from Tornado Bus Co - Dallas I-30 to Marathon Gas Station - Marion
- Ave. Duration
- 10h 50m
- Frequency
- Once daily
- Estimated price
- $110–240
- Schedules at
- tornadobus.com
- Adults 11-59
- $110–240
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from St. Louis to Carbondale
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $30–55
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Houston Bus Station to Dallas Bus Station
- Ave. Duration
- 4h 30m
- Frequency
- Every 4 hours
- Estimated price
- $40–85
- Website
- https://www.greyhound.com/
Bus from Dallas Bus Station to St Louis Bus Station
- Ave. Duration
- 15h 50m
- Frequency
- Once daily
- Estimated price
- $140–270
- Website
- https://www.greyhound.com/
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