There are 6 ways to get from Houston to Knoxville by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly from Houston  •  4 h 29 min

  1. Fly from Houston (IAH) to Knoxville (TYS) IAH - TYS

$316 - $623

Cheapest option

Bus, Megabus  •  22 h 6 min

  1. Take the bus from Houston, Tx to Atlanta, Ga 1596
  2. Take the Megabus from Atlanta GA to Knoxville

$104 - $233

4 alternative options

Fly from Houston Hobby Apt  •  5 h 52 min

  1. Fly from Houston Hobby Apt (HOU) to Knoxville (TYS) HOU - TYS

$306 - $1,271

Bus  •  21 h 56 min

  1. Take the bus from Houston, Tx to Atlanta, Ga 1596
  2. Take the bus from Atlanta, Ga to Knoxville, Tn 1104 / ...

$105 - $260

Train, bus, Megabus  •  26 h 55 min

  1. Take the train from Houston Amtrak to New Orleans Union Passenger Terminal Amtrak
  2. Take the train from New Orleans Union Passenger Terminal Amtrak to Birmingham Amtrak
  3. Take the bus from Birmingham, AL to Atlanta, GA - W Peachtree St @ Civic Center MARTA Station
  4. Take the Megabus from Atlanta GA to Knoxville

$152 - $378

Drive  •  15 h 17 min

  1. Drive from Houston to Knoxville 927.9 miles

$90 - $140

Questions & Answers

The cheapest way to get from Houston to Knoxville is to drive which costs $90 - $140 and takes 15 h 17 min.

More details

The quickest way to get from Houston to Knoxville is to fly which costs $310 - $650 and takes 4 h 29 min.

More details

The distance between Houston and Knoxville is 794 miles. The road distance is 927.9 miles.

Get driving directions

It takes approximately 4 h 29 min to get from Houston to Knoxville, including transfers.

More details

No, there is no direct bus from Houston to Knoxville. However, there are services departing from Houston, Tx and arriving at Knoxville, Tn via Atlanta, Ga. The journey, including transfers, takes approximately 21 h 56 min.

More details

What companies run services between Houston, TX, USA and Knoxville, TN, USA?

United Airlines, Delta and American Airlines fly from Houston to Knoxville hourly. Alternatively, you can take a bus from Houston to Knoxville via Atlanta, Ga in around 21 h 56 min.

Airlines
Delta
Website
delta.com
Flights from Houston to Knoxville via Atlanta
Ave. Duration
4 h 17 min
When
Every day
Estimated price
$210 - $1,100
Flights from Houston Hobby Apt to Knoxville via Atlanta
Ave. Duration
4 h 19 min
When
Every day
Estimated price
$250 - $1,200
American Airlines
Website
aa.com
Flights from Houston to Knoxville via Dallas/Ft.Worth
Ave. Duration
4 h 36 min
When
Every day
Estimated price
$240 - $1,100
Flights from Houston to Knoxville via Charlotte
Ave. Duration
4 h 38 min
When
Every day
Estimated price
$250 - $1,100
Flights from Houston Hobby Apt to Knoxville via Dallas/Ft.Worth
Ave. Duration
4 h 39 min
When
Every day
Estimated price
$280 - $1,300
United Airlines
Website
united.com
Flights from Houston to Knoxville
Ave. Duration
2 h 15 min
When
Every day
Estimated price
$500 - $1,100
Train operators
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Houston Amtrak to New Orleans Union Passenger Terminal Amtrak
Ave. Duration
9 h 30 min
Frequency
3 times a week
Estimated price
$60 - $160
Website
amtrak.com
Coach Seat
$60 - $90
Flexi Coach Seat
$100 - $160
Business Coach Seat
$110 - $160
Room
$260 - $370
Train from New Orleans Union Passenger Terminal Amtrak to Birmingham Amtrak
Ave. Duration
7 h 15 min
Frequency
Once daily
Estimated price
$55 - $160
Website
amtrak.com
Coach Seat
$55 - $90
Flexi Coach Seat
$100 - $150
Business Coach Seat
$110 - $160
Room
$260 - $360
Bus operators
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Houston, Tx to Atlanta, Ga
Ave. Duration
16 h 55 min
Frequency
Every 30 minutes
Estimated price
$75 - $200
Website
greyhound.com
Economy
$75 - $130
Flexible
$150 - $200
Bus from Atlanta, Ga to Knoxville, Tn
Ave. Duration
4 h 45 min
Frequency
Every 30 minutes
Estimated price
$26 - $65
Website
greyhound.com
Economy
$26 - $45
Flexible
$45 - $65
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from Atlanta GA to Knoxville
Ave. Duration
4 h 5 min
Frequency
Twice daily
Estimated price
$22 - $35
Schedules at
us.megabus.com
Bus from Birmingham, AL to Atlanta, GA - W Peachtree St @ Civic Center MARTA Station
Ave. Duration
3 h 5 min
Frequency
5 times a day
Estimated price
$15 - $26
Schedules at
us.megabus.com

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