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How to get fromHouston to Des Moinesby plane, bus (Greyhound, Flixbus), bus, train, car, bus (Flixbus), or bus (Greyhound)

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There are 7 ways to get from Houston to Des Moines by plane, bus (Greyhound, Flixbus), bus, train, car, bus (Flixbus), or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from William P. Hobby Airport

    best
    1. Fly from William P. Hobby Airport (HOU) to Des Moines (DSM)plane plane HOU - DSM
    3h 49m
    $208–1,022

  2. Line 102 bus to George Bush Intercontinental Airport, fly

    cheapest
    1. Take the bus from Travis St @ Texas Ave to Bush IAH Terminal Cbus bus
    2. Fly from George Bush Intercontinental Airport (IAH) to Des Moines (DSM)plane plane IAH - DSM
    4h 20m
    $160–725

  3. Bus via Dallas

    1. Take the bus from Houston, TX - 808 Jefferson St to Dallas, TX - 1376 Marilla Stbus bus
    2. Take the bus from Dallas Bus Station to Kansas City Bus Stationbus bus
    3. Take the bus from Kansas City to Des Moinesbus bus
    21h 14m
    $197–350

  4. Bus, train

    1. Take the bus from Houston to Longviewbus bus
    2. Take the train from Longview to St. Louistrain train
    3. Take the bus from St Louis Bus Station to Des Moinesbus bus
    28h 12m
    $322–603

  5. Drive 918.6 mi

    1. Drive from Houston to Des Moinescar car 918.6 mi
    15h 16m
    $168–243

  6. Bus

    1. Take the bus from Downtown Houston to Dentonbus bus
    2. Take the bus from Denton to Kansas City Bus Stationbus bus
    3. Take the bus from Kansas City to Des Moinesbus bus
    21h 15m
    $172–293

  7. Bus #2

    1. Take the bus from Houston Bus Station to San Antonio Bus Stationbus bus
    2. Take the bus from San Antonio to Omahabus bus
    3. Take the bus from Omaha, NE to Des Moinesbus bus
    28h 18m
    $295–341

Houston to Des Moines by bus and train

Calendar7Weekly Services
Duration28h 12mAverage Duration
Ticket$322Cheapest Price
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Questions & Answers

Map of how to get from Houston to Des Moines.ExpandLaunch map view
  • Distance: 842.1 mi
  • Duration: 3h 49m

What companies run services between Houston, TX, USA and Des Moines, IA, USA?

Allegiant Air, American Airlines, and two other airlines fly from William P. Hobby Airport (HOU) to Des Moines (DSM) 5 times a day. Alternatively, you can take a bus from Houston, TX - 808 Jefferson St to Des Moines via Marilla @ Akard - W - Fs, Rosa Parks Plaza, West End Station, Bachman Station, Dallas Bus Station, and Kansas City in around 21h 14m.

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