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Santa Cruz do Capibaribe is a Brazilian municipality in the State of Pernambuco. It is the third largest city in the mesoregion of Agreste of Pernambuco with a population of 105,936 inhabitants in 2018. It has 335.309 km² (208.5 square miles) of total area and it is located about 185.7 km (115.4 miles) from the capital Recife.