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Ancona is a city and a seaport in the Marche region in central Italy, with a population of around 101,997. Ancona is the capital of the province of Ancona and of the region. The city is located 280 km northeast of Rome, on the Adriatic Sea, between the slopes of the two extremities of the promontory of Monte Conero, Monte Astagno and Monte Guasco.