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About La Crosse

La Crosse is a city in the U.S. state of Wisconsin and the county seat of La Crosse County. Positioned alongside the Mississippi River, La Crosse is the largest city on Wisconsin's western border. La Crosse's estimated population in 2018 was 51,567. The city forms the core of and is the principal city in the La Crosse Metropolitan Area, which includes all of La Crosse County and Houston County, Minnesota, for a population of 135,298.

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