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High Point is a city located in the Piedmont Triad region of the U.S. state of North Carolina. Most of the city is located in Guilford County, with portions extending into neighboring Randolph, Davidson, and Forsyth counties. High Point is North Carolina's only city that extends into four counties. As of the 2010 census the city had a total population of 104,371, with an estimated population of 112,316 in 2018. High Point is currently the ninth-largest municipality in North Carolina, and the 259th largest city in America.