Greenville is a city in and the seat of Greenville County, South Carolina, United States. The city's mayor is Knox H. White, who has been in that position since December 1995. With an estimated population of 68,563 as of 2018, it is the sixth-largest city in the state. The population of the surrounding area was 400,492 as of 2010, making it the third-largest urban area in South Carolina as well as the fastest growing. Greenville is the largest city in the Greenville-Anderson-Mauldin Metropolitan Statistical Area. The MSA had a population of 920,477 in 2019, making it the largest in South Carolina and the third largest in the Carolinas.