Grand Island is a town located in Erie County, New York, United States. As of the 2010 census, the town's population was 20,374, representing an increase of 9.41% from the 2000 census figure. The town's name derives from the French name La Grande Île, as Grand Island is the largest island in the Niagara River and third largest in New York state. The phrase La Grande Île appears on the town seal.