Rome2Rio uses cookies to help personalize content and show you personalised ads. By proceeding, you accept the use of cookies in accordance with our privacy policy. You may opt out of personalised ads at any time. OK

About Farmington

Farmington is a city in St. Francois County located about 75 mi southwest of St. Louis in the Lead Belt region in Missouri. As of the 2020 census, the population was 18,217. It is the county seat of St. Francois County. Farmington was established in 1822 as Murphy's Settlement, named for William Murphy of Kentucky, who first visited the site in 1798. When St. Francois County was organized, the town was briefly called St. Francois Court House and later renamed to Farmington.

Get the Rome2Rio app

Find the best way to get from A to B, anywhere in the world, on your mobile or tablet.

Compare your options: plane, train, bus, car, ferry, bike share, driving and walking directions all in one search.

Learn more about our apps