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Fabriano is a town and comune of Ancona province in the Italian region of the Marche, at 325 m above sea level. It lies in the Esino valley 44 km upstream and southwest of Jesi; and 15 km east-northeast of Fossato di Vico and 36 km east of Gubbio (both in Umbria). Its location on the main highway and rail line from Umbria to the Adriatic make it a mid-sized regional center in the Apennines. Fabriano is the headquarters of the giant appliance maker Indesit.