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Molise is a region of Southern Italy. Until 1963, it formed part of the region of Abruzzi e Molise, alongside the region of Abruzzo. The split, which did not become effective until 1970, makes Molise the youngest region in Italy. Covering 4438 km2, it is the second smallest region in the country after the Aosta Valley, and has a population of 313,348 (as of 1 January 2015).