There are 5 ways to get from Hopkinton to Buffalo by train, plane, bus (Greyhound, Flixbus), train (Amtrak), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, fly to Buffalo Niagara International Airport
best- Take the train from Framingham to South Station
- Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)BOS - BUF
6h 18m$160–1,068Train (Amtrak)
cheapest- Take the train from Framingham Amtrak to Buffalo Depew StationLake Shore Limited
13h 50m$56–236Bus
- Take the bus from Framingham to Springfield Union Station
- Take the bus from Springfield Union Station to Syracuse Bus Station
- Take the bus from Syracuse Bus Station to Buffalo
12h 23m$88–156Drive 431 mi
- Drive from Hopkinton to Buffalo431 mi
7h 27m$79–114Train, fly to Rochester, bus
- Take the train from Framingham to South Station
- Fly from Boston Logan Airport (BOS) to Rochester (ROC)BOS - ROC
- Take the bus from Rochester, NY to Buffalo, NY
8h 17m$220–674
Hopkinton to Buffalo by bus
Questions & Answers
The cheapest way to get from Hopkinton to Buffalo is to drive which costs $75 - $120 and takes 7h 27m.
The fastest way to get from Hopkinton to Buffalo is to train and fly which takes 6h 18m and costs $160 - $1,100.
No, there is no direct bus from Hopkinton to Buffalo. However, there are services departing from Hopkinton Center and arriving at Buffalo via Framingham, Springfield Union Station and Syracuse Bus Station. The journey, including transfers, takes approximately 12h 23m.
The distance between Hopkinton and Buffalo is 442 miles. The road distance is 433.5 miles.
The best way to get from Hopkinton to Buffalo without a car is to bus which takes 12h 23m and costs $85 - $160.
It takes approximately 6h 18m to get from Hopkinton to Buffalo, including transfers.
Hopkinton to Buffalo bus services, operated by Greyhound USA, depart from Framingham station.
The best way to get from Hopkinton to Buffalo is to bus which takes 12h 23m and costs $85 - $160. Alternatively, you can train, which costs $55 - $240 and takes 13h 50m.
Hopkinton to Buffalo bus services, operated by Greyhound USA, arrive at Springfield Union Station.
Yes, the driving distance between Hopkinton to Buffalo is 433 miles. It takes approximately 7h 27m to drive from Hopkinton to Buffalo.
What companies run services between Hopkinton, MA, USA and Buffalo, NY, USA?
You can take a bus from Hopkinton Center to Buffalo via Framingham MBTA Station, Framingham, Springfield Union Station, and Syracuse Bus Station in around 12h 23m. Alternatively, Amtrak operates a train from Framingham Amtrak to Buffalo Depew Station once daily. Tickets cost $45–160 and the journey takes 11h 4m.
- Website
- aa.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 47m
- When
- Sunday
- Estimated price
- $150–950
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 4h 8m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $200–1,200
Flights from Boston Logan Airport to Rochester
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $75–470
Flights from Boston Logan Airport to Rochester via Philadelphia
- Ave. Duration
- 4h 6m
- When
- Every day
- Estimated price
- $90–550
- Website
- southwest.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- $190–1,100
Flights from Boston Logan Airport to Rochester via Baltimore
- Ave. Duration
- 4h 1m
- When
- Monday, Friday, and Saturday
- Estimated price
- $100–600
- Website
- delta.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 3h 54m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $170–1,000
Flights from Boston Logan Airport to Rochester via New York La Guardia
- Ave. Duration
- 3h 57m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–500
Flights from Boston Logan Airport to Rochester via New York JFK
- Ave. Duration
- 4h 3m
- When
- Monday to Wednesday
- Estimated price
- $85–500
- Website
- jetblue.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 42m
- When
- Every day
- Estimated price
- $150–950
Flights from Boston Logan Airport to Buffalo Niagara International Airport via New York JFK
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $170–1,000
Flights from Boston Logan Airport to Rochester via New York JFK
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- $85–500
- Website
- united.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Newark
- Ave. Duration
- 4h 4m
- When
- Every day
- Estimated price
- $170–1,000
Flights from Boston Logan Airport to Rochester via Newark
- Ave. Duration
- 4h 1m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–500
- Phone
- +1-617-222-3200
- Website
- mbta.com
Train from Framingham to South Station
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- $3–10
- Website
- https://www.mbta.com
- Adult
- $3–10
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Framingham Amtrak to Buffalo Depew Station
- Ave. Duration
- 11h 4m
- Frequency
- Once daily
- Estimated price
- $45–160
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $45–120
- Coach Seat short notice purchase
- $60–160
- Business - advance purchase
- $80–350
- Business Class
- $130–380
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Framingham to Springfield Union Station
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $22–35
- Website
- https://www.greyhound.com/
Bus from Springfield Union Station to Syracuse Bus Station
- Ave. Duration
- 4h 50m
- Frequency
- Once daily
- Estimated price
- $40–75
- Website
- https://www.greyhound.com/
Bus from Syracuse Bus Station to Buffalo
- Ave. Duration
- 3h 20m
- Frequency
- 4 times a day
- Estimated price
- $27–45
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Springfield Union Station to Syracuse Bus Station
- Ave. Duration
- 4h 35m
- Frequency
- 6 times a week
- Estimated price
- $40–65
- Schedules at
- flixbus.com
Bus from Syracuse Bus Station to Buffalo
- Ave. Duration
- 2h 55m
- Frequency
- Every 4 hours
- Estimated price
- $27–40
- Schedules at
- flixbus.com
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Syracuse Bus Station to Buffalo
- Ave. Duration
- 3h 10m
- Frequency
- 4 times a day
- Estimated price
- $25–40
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Phone
- +1-844-800-6828
- pr@ourbus.com
- Website
- ourbus.com
Bus from Rochester, NY to Buffalo, NY
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- $20–55
- Website
- https://www.ourbus.com
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