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How to get fromHopkinton to Buffaloby train, plane, bus (Greyhound, Flixbus), train (Amtrak), car or bus

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There are 5 ways to get from Hopkinton to Buffalo by train, plane, bus (Greyhound, Flixbus), train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, fly to Buffalo Niagara International Airport

    best
    1. Take the train from Framingham to South Stationtrain
    2. Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)planeBOS - BUF
    6h 18m
    $160–1,068
  2. Train (Amtrak)

    cheapest
    1. Take the train from Framingham Amtrak to Buffalo Depew StationtrainLake Shore Limited
    13h 50m
    $56–236
  3. Bus

    1. Take the bus from Framingham to Springfield Union Stationbus
    2. Take the bus from Springfield Union Station to Syracuse Bus Stationbus
    3. Take the bus from Syracuse Bus Station to Buffalobus
    12h 23m
    $88–156
  4. Drive 431 mi

    1. Drive from Hopkinton to Buffalocar431 mi
    7h 27m
    $79–114
  5. Train, fly to Rochester, bus

    1. Take the train from Framingham to South Stationtrain
    2. Fly from Boston Logan Airport (BOS) to Rochester (ROC)planeBOS - ROC
    3. Take the bus from Rochester, NY to Buffalo, NYbus
    8h 17m
    $220–674

Hopkinton to Buffalo by bus

Calendar7Weekly Buses
Duration12h 23mAverage Duration
Ticket$88Cheapest Price
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Questions & Answers

What companies run services between Hopkinton, MA, USA and Buffalo, NY, USA?

You can take a bus from Hopkinton Center to Buffalo via Framingham MBTA Station, Framingham, Springfield Union Station, and Syracuse Bus Station in around 12h 23m. Alternatively, Amtrak operates a train from Framingham Amtrak to Buffalo Depew Station once daily. Tickets cost $45–160 and the journey takes 11h 4m.

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