There are 5 ways to get from Hopkinton to Buffalo by train, plane, bus (Greyhound, Flixbus), train (Amtrak), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, fly to Buffalo Niagara International Airport
best- Take the train from Framingham to South Stationtrain
- Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane BOS - BUF
6h 15m$140–966Bus
cheapest- Take the bus from Framingham to Springfield Union Stationbus
- Take the bus from Springfield Union Station to Syracuse Bus Stationbus
- Take the bus from Syracuse Bus Station to Buffalobus
12h 30m$58–144Train (Amtrak)
- Take the train from Framingham Amtrak to Buffalo Depew Stationtrain Lake Shore Limited
13h 48m$110–326Drive 431 mi
- Drive from Hopkinton to Buffalocar 431 mi
7h 29m$79–114Fly to Rochester, bus
- Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane BOS - ROC
- Take the bus from Rochester Bus Stop to Buffalobus
7h 23m$242–832
Hopkinton to Buffalo by bus
Questions & Answers
The cheapest way to get from Hopkinton to Buffalo is to bus which costs $55 - $150 and takes 12h 30m.
The fastest way to get from Hopkinton to Buffalo is to train and fly which takes 6h 15m and costs $140 - $1,000.
No, there is no direct bus from Hopkinton to Buffalo. However, there are services departing from Hopkinton Center and arriving at Buffalo via Framingham, Springfield Union Station and Syracuse Bus Station. The journey, including transfers, takes approximately 12h 30m.
The distance between Hopkinton and Buffalo is 444 miles. The road distance is 433.5 miles.
The best way to get from Hopkinton to Buffalo without a car is to bus which takes 12h 30m and costs $55 - $150.
It takes approximately 6h 15m to get from Hopkinton to Buffalo, including transfers.
Hopkinton to Buffalo bus services, operated by Greyhound USA, depart from Framingham station.
The best way to get from Hopkinton to Buffalo is to bus which takes 12h 30m and costs $55 - $150. Alternatively, you can train, which costs $110 - $330 and takes 13h 48m.
Hopkinton to Buffalo bus services, operated by Greyhound USA, arrive at Springfield Union Station.
Yes, the driving distance between Hopkinton to Buffalo is 433 miles. It takes approximately 7h 29m to drive from Hopkinton to Buffalo.
What companies run services between Hopkinton, MA, USA and Buffalo, NY, USA?
You can take a bus from Hopkinton Center to Buffalo via Framingham MBTA Station, Framingham, Springfield Union Station, and Syracuse Bus Station in around 12h 30m. Alternatively, Amtrak operates a train from Framingham Amtrak to Buffalo Depew Station once daily. Tickets cost $100–250 and the journey takes 11h 4m.
- Website
- aa.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 47m
- When
- Every day
- Estimated price
- $130–900
Flights from Boston Logan Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 4h 17m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–950
Flights from Boston Logan Airport to Rochester
- Ave. Duration
- 1h 39m
- When
- Every day
- Estimated price
- $75–500
- Website
- united.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 4h 6m
- When
- Every day
- Estimated price
- $180–1,100
Flights from Boston Logan Airport to Rochester via Newark
- Ave. Duration
- 3h 53m
- When
- Monday to Saturday
- Estimated price
- $85–550
Flights from Boston Logan Airport to Rochester via Washington Dulles
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- $110–650
- Website
- delta.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 3h 55m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–950
Flights from Boston Logan Airport to Rochester via New York La Guardia
- Ave. Duration
- 4h 2m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $85–550
- Website
- jetblue.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $130–900
Flights from Boston Logan Airport to Buffalo Niagara International Airport via New York JFK
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $150–950
- Website
- southwest.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 4h
- When
- Tuesday and Wednesday
- Estimated price
- $180–1,100
- Phone
- +1-617-222-3200
- Website
- mbta.com
Train from Framingham to South Station
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Estimated price
- $3–10
- Website
- https://www.mbta.com
- Adult
- $3–10
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Framingham Amtrak to Buffalo Depew Station
- Ave. Duration
- 11h 4m
- Frequency
- Once daily
- Estimated price
- $100–250
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Framingham to Springfield Union Station
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $12–23
- Website
- https://www.greyhound.com/
Bus from Springfield Union Station to Syracuse Bus Station
- Ave. Duration
- 4h 50m
- Frequency
- Once daily
- Estimated price
- $35–70
- Website
- https://www.greyhound.com/
Bus from Syracuse Bus Station to Buffalo
- Ave. Duration
- 3h 20m
- Frequency
- 4 times a day
- Estimated price
- $25–50
- Website
- https://www.greyhound.com/
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 25m
- Frequency
- 4 times a day
- Estimated price
- $11–22
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Springfield Union Station to Syracuse Bus Station
- Ave. Duration
- 4h 30m
- Frequency
- 5 times a week
- Estimated price
- $27–50
- Schedules at
- flixbus.com
Bus from Syracuse Bus Station to Buffalo
- Ave. Duration
- 2h 55m
- Frequency
- Every 4 hours
- Estimated price
- $18–35
- Schedules at
- flixbus.com
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 20m
- Frequency
- Every 3 hours
- Estimated price
- $8–15
- Schedules at
- flixbus.com
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Syracuse Bus Station to Buffalo
- Ave. Duration
- 3h 10m
- Frequency
- 5 times a day
- Estimated price
- $28–95
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $28–90
- Flexible
- $55–95
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