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How to get fromHopkinton to Buffaloby train, plane, bus (Greyhound), train (Amtrak), car, bus or bus (Flixbus)

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There are 6 ways to get from Hopkinton to Buffalo by train, plane, bus (Greyhound), train (Amtrak), car, bus, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, fly to Buffalo Niagara International Airport

    best
    1. Take the train from Framingham to South Stationtrain train
    2. Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane plane BOS - BUF
    6h 1m
    $142–966
  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Framingham to Springfield Union Stationbus bus Greyhound US0270s
    2. Take the bus from Springfield Union Station to Buffalobus bus Greyhound US0171
    12h 18m
    $74–156
  3. Train (Amtrak)

    1. Take the train from Framingham Amtrak to Buffalo Depew Stationtrain train Lake Shore Limited
    13h 48m
    $130–356
  4. Drive 431 mi

    1. Drive from Hopkinton to Buffalocar car 431 mi
    7h 29m
    $79–114
  5. Fly to Rochester, bus

    1. Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane plane BOS - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    7h 23m
    $264–834
  6. Bus via Ithaca

    1. Take the bus from Boston to Ithacabus bus FlixBus 2691
    2. Take the bus from Ithaca to Buffalobus bus FlixBus N2687 / ...
    15h 14m
    $78–196

Hopkinton to Buffalo by bus (Greyhound)

Calendar7Weekly Buses
Duration12h 18mAverage Duration
Ticket$74Cheapest Price
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Questions & Answers

What companies run services between Hopkinton, MA, USA and Buffalo, NY, USA?

You can take a bus from Hopkinton Center to Buffalo via Framingham MBTA Station, Framingham, and Springfield Union Station in around 12h 18m. Alternatively, Amtrak operates a train from Framingham Amtrak to Buffalo Depew Station once daily. Tickets cost $120–280 and the journey takes 11h 4m.

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