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How to get fromHomosassa to Florida Keysby car, plane, taxi, bus, train or shuttle

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There are 9 ways to get from Homosassa to Florida Keys by car, plane, taxi, bus, train, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Tampa, fly to Key West International Airport

    best
    1. Drive from Homosassa to Tampa (TPA)car
    2. Fly from Tampa (TPA) to Key West International Airport (EYW)planeTPA - EYW
    5h 18m
    $170–587

  2. Drive 426.4 mi

    cheapest
    1. Drive from Homosassa to Florida Keyscar426.4 mi
    8h 43m
    $78–113

  3. Taxi, bus

    1. Take the taxi from Homosassa to Ocalataxi
    2. Take the bus from Ocala to Miami Airportbus
    3. Take the bus from Miami Airport Station to Big Pine Keybus
    12h 54m
    $187–282

  4. Drive, train, bus

    1. Drive from Homosassa to Tampacar
    2. Take the train from Tampa to Miami Amtrak Stationtrain
    3. Take the bus from Miami Airport Station to Big Pine Keybus
    13h 3m
    $86–220

  5. Drive to Saint Petersburg–Clearwater International Airport, fly to Key West International Airport

    1. Drive from Homosassa to Saint Petersburg–Clearwater International Airport (PIE)car
    2. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Key West International Airport (EYW)planePIE - EYW
    5h 24m
    $105–408

  6. Drive to Tampa, fly to Miami International Airport, shuttle

    1. Drive from Homosassa to Tampa (TPA)car
    2. Fly from Tampa (TPA) to Miami International Airport (MIA)planeTPA - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle
    7h 54m
    $245–542

  7. Drive to Tampa, fly to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Drive from Homosassa to Tampa (TPA)car
    2. Fly from Tampa (TPA) to Fort Lauderdale–Hollywood International Airport (FLL)planeTPA - FLL
    3. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle
    8h 24m
    $205–332

  8. Taxi, bus, train

    1. Take the taxi from Homosassa to Ocalataxi
    2. Take the bus from Ocala to West Palm Beach, FLbus
    3. Take the train from West Palm Beach Station to Miami Airport Stationtrain
    4. Take the bus from Miami Airport Station to Big Pine Keybus
    14h 5m
    $186–283

  9. Bus, taxi, shuttle

    1. Take the bus from W Yulee Dr & S Mason Creek Rd to Citrus County Transit Officebus
    2. Take the taxi from Citrus County Transit Office to TA Travel Center - Wildwood, FLtaxi
    3. Take the bus from TA Travel Center - Wildwood, FL to Dolphin Mall - Miamibus
    4. Take a shuttle bus from Bayside Marketplace to Plaza Hotelshuttle
    19h 6m
    $223–365

Tampa (TPA) to Key West International Airport (EYW) flights

Calendar13Weekly Planes
Duration1h 38mAverage Duration
Ticket$44Cheapest Price
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Questions & Answers

What companies run services between Homosassa, FL, USA and Florida Keys, FL, USA?

There is no direct connection from Homosassa to Florida Keys. However, you can drive to Tampa (TPA) airport, fly to Key West International Airport (EYW), walk to Key West Airport, take the shuttle to Key West, FL, walk to Whitehead & Eaton, take the bus to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge, then walk to Florida Keys. Alternatively, you can take the taxi to Ocala, take the bus to Miami Airport, walk to Miami International Airport, take the vehicle to Miami Airport Station, walk to Miami, Airport Intermodal Station, take the bus to Big Pine Key, walk to Big Pine Key - CVS / MM30, take the bus to Sugarloaf Key - Lower - Sugarloaf Lodge, then walk to Florida Keys.

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