There are 11 ways to get from Homosassa to Florida Keys by taxi, shuttle, plane, bus, car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi, shuttle to Tampa, fly to Key West International Airport
best- Take the taxi from Homosassa to Brooksville Wawa
- Take a shuttle bus from Brooksville Wawa to Tampa International Airport - Red Terminal
- Fly from Tampa (TPA) to Key West International Airport (EYW)TPA - EYW
6h 47m$280–724Drive 426.4 mi
cheapest- Drive from Homosassa to Florida Keys426.4 mi
8h 43m$78–113Taxi, bus
- Take the taxi from Homosassa to Ocala
- Take the bus from Ocala to Miami Airport
- Take the bus from Miami Airport Station to Big Pine Key
12h 54m$187–293Drive, train, bus
- Drive from Homosassa to Tampa
- Take the train from Tampa to Miami Amtrak Station
- Take the bus from Miami Airport Station to Big Pine Key
13h 3m$84–231Taxi, shuttle to Orlando, fly to Key West International Airport
- Take the taxi from Homosassa to Brownwood Hotel & Spa
- Take a shuttle bus from Brownwood Hotel & Spa to MCO Airport - Terminal A
- Fly from Orlando (MCO) to Key West International Airport (EYW)MCO - EYW
7h 15m$318–830Taxi, shuttle to Tampa, fly to Miami International Airport, shuttle
- Take the taxi from Homosassa to Brooksville Wawa
- Take a shuttle bus from Brooksville Wawa to Tampa International Airport - Red Terminal
- Fly from Tampa (TPA) to Miami International Airport (MIA)TPA - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
9h 22m$355–679Drive to Orlando Sanford, fly to Key West International Airport
- Drive from Homosassa to Orlando-Sanford-Airport-SFB
- Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)SFB - EYW
6h 18m$114–413Taxi, shuttle to Tampa, fly to Fort Lauderdale–Hollywood International Airport, shuttle
- Take the taxi from Homosassa to Brooksville Wawa
- Take a shuttle bus from Brooksville Wawa to Tampa International Airport - Red Terminal
- Fly from Tampa (TPA) to Fort Lauderdale–Hollywood International Airport (FLL)TPA - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
9h 51m$310–469Taxi, shuttle, line 300 bus to Saint Petersburg–Clearwater International Airport, fly to Key West International Airport, bus
- Take the taxi from Homosassa to Brooksville Wawa
- Take a shuttle bus from Brooksville Wawa to Tampa International Airport - Red Terminal
- Take the bus from TPA RENTAL CAR FACILITY westbound to Psta 34Th St Layby - Platform - B
- Fly from Saint Petersburg–Clearwater International Airport (PIE) to Key West International Airport (EYW)PIE - EYW
- Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge
9h 4m$221–540Taxi, bus, train
- Take the taxi from Homosassa to Ocala
- Take the bus from Ocala to West Palm Beach, FL
- Take the train from West Palm Beach Station to Miami Airport Station
- Take the bus from Miami Airport Station to Big Pine Key
14h 5m$186–294Taxi, shuttle, bus
- Take the taxi from Homosassa to Brooksville Wawa
- Take a shuttle bus from Brooksville Wawa to Tampa International Airport - Red Terminal
- Take the bus from Tampa Bus Station to Fort Lauderdale International Airport
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Summerland Key - Mote Marine Lab
15h 23m$312–437
Tampa (TPA) to Key West International Airport (EYW) flights
Questions & Answers
The cheapest way to get from Homosassa to Florida Keys is to drive which costs $75 - $120 and takes 8h 43m.
The fastest way to get from Homosassa to Florida Keys is to drive and fly which takes 6h 18m and costs $110 - $420.
The distance between Homosassa and Florida Keys is 351 miles. The road distance is 428.9 miles.
The best way to get from Homosassa to Florida Keys without a car is to taxi and bus which takes 12h 54m and costs $180 - $300.
It takes approximately 6h 47m to get from Homosassa to Florida Keys, including transfers.
Yes, the driving distance between Homosassa to Florida Keys is 429 miles. It takes approximately 8h 43m to drive from Homosassa to Florida Keys.
There are 774+ hotels available in Florida Keys.
What companies run services between Homosassa, FL, USA and Florida Keys, FL, USA?
There is no direct connection from Homosassa to Florida Keys. However, you can take the taxi to Brooksville Wawa, take the shuttle to Tampa International Airport - Red Terminal, walk to Tampa (TPA) airport, fly to Key West International Airport (EYW), walk to Key West Airport, take the shuttle to Key West, FL, walk to Whitehead & Eaton, take the bus to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge, then walk to Florida Keys. Alternatively, you can take the taxi to Ocala, take the bus to Miami Airport, walk to Miami International Airport, take the vehicle to Miami Airport Station, walk to Miami, Airport Intermodal Station, take the bus to Big Pine Key, walk to Big Pine Key - CVS / MM30, take the bus to Sugarloaf Key - Lower - Sugarloaf Lodge, then walk to Florida Keys.
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- Website
- aa.com
Flights from Tampa to Key West International Airport via Miami International Airport
- Ave. Duration
- 3h 2m
- When
- Every day
- Estimated price
- $45–290
Flights from Orlando to Key West International Airport via Miami International Airport
- Ave. Duration
- 3h 24m
- When
- Every day
- Estimated price
- $40–260
Flights from Tampa to Miami International Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- $30–230
- Website
- allegiantair.com
Flights from Orlando Sanford to Key West International Airport
- Ave. Duration
- 1h 17m
- When
- Thursday and Sunday
- Estimated price
- $50–320
Flights from Saint Petersburg–Clearwater International Airport to Key West International Airport
- Ave. Duration
- 1h 2m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $45–310
- Website
- flybreeze.com
Flights from Tampa to Key West International Airport
- Ave. Duration
- 1h 7m
- When
- Every day
- Estimated price
- $110–500
Flights from Orlando to Key West International Airport
- Ave. Duration
- 1h 15m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $110–600
- Website
- spirit.com
Flights from Tampa to Key West International Airport via Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 11m
- When
- Thursday, Saturday, and Sunday
- Estimated price
- $95–380
Flights from Tampa to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 6m
- When
- Every day
- Estimated price
- $35–110
- Website
- southwest.com
Flights from Tampa to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- $26–170
- Website
- jetblue.com
Flights from Tampa to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 4m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $26–170
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Tampa to Miami Amtrak Station
- Ave. Duration
- 5h 26m
- Frequency
- Once daily
- Estimated price
- $25–140
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 800-874-7245
- Website
- tri-rail.com
Train from West Palm Beach Station to Miami Airport Station
- Ave. Duration
- 1h 49m
- Frequency
- Hourly
- Estimated price
- $5–11
- Website
- https://www.tri-rail.com
- Weekend | Holiday
- $5
- Weekday
- $8–11
- Phone
- +1 352 539 9664
- Website
- groometransportation.com
Shuttle from Brooksville Wawa to Tampa International Airport - Red Terminal
- Ave. Duration
- 1h 10m
- Frequency
- Hourly
- Estimated price
- $35–50
- Website
- https://groometransportation.com/the-villages/?&sd_client_id=992f7c93-d719-43a2-9d9e-8c8cbbd08d74
- online discount
- $35–45
- call in
- $40–50
Shuttle from Brownwood Hotel & Spa to MCO Airport - Terminal A
- Ave. Duration
- 1h 10m
- Frequency
- Hourly
- Estimated price
- $35–50
- Website
- https://groometransportation.com/the-villages/?&sd_client_id=992f7c93-d719-43a2-9d9e-8c8cbbd08d74
- online discount
- $35–45
- call in
- $40–50
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Ocala to Miami Airport
- Ave. Duration
- 5h 40m
- Frequency
- Every 2 hours
- Estimated price
- $30–90
- Website
- https://www.redcoachusa.com
- Web
- $30–90
Bus from Ocala to West Palm Beach, FL
- Ave. Duration
- 4h 35m
- Frequency
- 3 times a day
- Estimated price
- $24–80
- Website
- https://www.redcoachusa.com
- Web
- $24–80
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Estimated price
- $21–40
- Website
- https://www.greyhound.com/
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h
- Frequency
- 4 times a day
- Estimated price
- $130–180
- Website
- https://www.keysshuttle.com
Shuttle from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h 30m
- Frequency
- 4 times a day
- Estimated price
- $150–200
- Website
- https://www.keysshuttle.com
Shuttle from Fort Lauderdale, FL - International Airport to Summerland Key - Mote Marine Lab
- Ave. Duration
- 4h
- Frequency
- 4 times a day
- Estimated price
- $150–210
- Website
- https://www.keysshuttle.com
- Phone
- +1 727-540-1900
- ride@psta.net
- Website
- psta.net
Bus from TPA RENTAL CAR FACILITY westbound to Psta 34Th St Layby - Platform - B
- Ave. Duration
- 32 min
- Frequency
- Every 4 hours
- Estimated price
- $3
- Schedules at
- psta.net
- Adult
- $3
- Phone
- +1 (305) 600-1455
- Website
- cityofkeywest-fl.gov
Bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge
- Ave. Duration
- 36 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Tampa Bus Station to Fort Lauderdale International Airport
- Ave. Duration
- 5h 25m
- Frequency
- 3 times a day
- Estimated price
- $35–65
- Schedules at
- flixbus.com
- Ave. Duration
- 42 min
- Estimated price
- $85–170
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