From Holyhead train to Crewe then train to Stoke-on-Trent. 3 h 7 min £70. From Holyhead train to Stafford then train to Stoke-on-Trent. 3 h 18 min £73. From Holyhead bus and ferry to Chester, walk to Chester, then bus to Stoke-On-Trent. 6 h 5 min £28. From Holyhead drive to Stoke-on-Trent. 2 h 17 min £24.
Train from Holyhead to Stoke-on-Trent
Virgin West Coast Trains operates a train from Holyhead to Stoke-on-Trent every 4 hours. Tickets cost $65 - $110 and the journey takes 1 h 59 min. West Midlands also services this route hourly.