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There are 11 ways to get from Holyhead to Sicily by train, plane, bus, ferry, bus and ferry or night train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train, train to Manchester, fly to Catania  •  10h 33m

  1. Take the train from Holyhead to Chester
  2. Take the train from Chester to Manchester Airport
  3. Fly from Manchester (MAN) to Catania (CTA) MAN - CTA

€101 - €355

Cheapest option

Train to Liverpool, fly to Palermo  •  11h 58m

  1. Take the train from Holyhead to Chester
  2. Fly from Liverpool (LPL) to Palermo (PMO) LPL - PMO

€80 - €324

9 alternative options

Train, train to Manchester, fly to Palermo  •  10h 35m

  1. Take the train from Holyhead to Chester
  2. Take the train from Chester to Manchester Airport
  3. Fly from Manchester (MAN) to Palermo (PMO) MAN - PMO

€99 - €356

Train to Liverpool, fly to Catania  •  11h 46m

  1. Take the train from Holyhead to Chester
  2. Fly from Liverpool (LPL) to Catania (CTA) LPL - CTA

€81 - €313

Train to London Heathrow, fly to Catania  •  10h 10m

  1. Take the train from Holyhead to London Euston
  2. Fly from London Heathrow (LHR) to Catania (CTA) LHR - CTA

€177 - €661

Train to London Stansted, fly to Palermo  •  10h 54m

  1. Take the train from Holyhead to London Euston
  2. Fly from London Stansted (STN) to Palermo (PMO) STN - PMO

€158 - €502

Train, train to Bristol, fly to Catania  •  12h 9m

  1. Take the train from Holyhead to Crewe
  2. Take the train from Crewe to Birmingham New Street
  3. Take the train from Birmingham New Street to Bristol Temple Meads
  4. Fly from Bristol (BRS) to Catania (CTA) BRS - CTA

€168 - €664

Train to Liverpool, fly to Comiso  •  11h 45m

  1. Take the train from Holyhead to Chester
  2. Fly from Liverpool (LPL) to Comiso (CIY) LPL - CIY

€102 - €370

Train, bus, ferry  •  2 days 4h

  1. Take the train from Holyhead to London Euston
  2. Take the bus from London, Victoria Green Line Station to Luxembourg, P+R Bouillon
  3. Take the bus from Luxembourg, P+R Bouillon to Genoa
  4. Take the ferry from Genoa to Palermo

€252 - €617

Train, bus and ferry, night train  •  2 days 5h

  1. Take the train from Holyhead to London Euston
  2. Take the bus and ferry from London to Salzburg
  3. Take the night train from Salzburg Hbf to Roma Termini Nj
  4. Take the train from Roma Termini to Palermo Centrale Ic

€286 - €638

Train, bus  •  2 days 17h

  1. Take the train from Holyhead to London Euston
  2. Take the bus from London Victoria to Legnica
  3. Take the bus from Legnica to Palermo

€231 - €563

United Kingdom → Italy
Partially open

Travel safe during COVID-19

International entry into Italy from United Kingdom

  • Entry is partially open for citizens and permanent residents of United Kingdom
Show more details
Allowed for: Citizens and permanent residents of Italy, as well as residents from EU Schengen Area (EU countries, Iceland, Liechtenstein, Norway, and Switzerland), Andorra, Australia, Canada, Cyprus, Israel, Japan, Monaco, New Zealand, Rwanda, San Marino, Singapore, South Korea, Thailand, United Kingdom, United States and Vatican

Restricted for: Foreign nationals from outside EU Schengen Area with the above exceptions. Brazil, India, Bangladesh and Sri Lanka are also restricted

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Conditions of entry into Italy from United Kingdom

  • Negative COVID-19 test issued at most 2 days before arrival or 10 day mandatory self-quarantine
  • 5-day mandatory self-quarantine and COVID-19 test at the end of the isolation period
  • Passenger Locator Form (PLF) required
This applies to arrivals from United Kingdom
Show more details
  • 10-day mandatory quarantine and a negative COVID-19 test issued at most 3 days before arrival
  • 10-day mandatory self-quarantine and COVID-19 test at the end of the isolation period
This applies to arrivals from Australia, Canada, Japan, New Zealand, Rwanda, Singapore, South Korea, Thailand and United States
  • Negative COVID-19 test issued at most 2 days before arrival or 10 day mandatory self-quarantine
This applies to arrivals from Andorra, Austria, Belgium, Bulgaria, Croatia, Cyprus, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Iceland, Ireland, Israel, Latvia, Liechtenstein, Lithuania, Luxembourg, Malta, Monaco, Netherlands, Norway, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, Switzerland and United Kingdom
  • 5-day mandatory self-quarantine and COVID-19 test at the end of the isolation period
This applies to arrivals from United Kingdom
  • Travellers with a certificate of vaccination are exempt from providing a negative COVID-19 test
This applies to arrivals from Andorra, Austria, Belgium, Bulgaria, Croatia, Cyprus, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Iceland, Ireland, Israel, Latvia, Liechtenstein, Lithuania, Luxembourg, Malta, Monaco, Netherlands, Norway, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden and Switzerland
  • Travellers with the Digital Green Certificate are exempt from the quarantine. Digital Green Certificate is proof that a person has been vaccinated against COVID-19, received a negative test result, or recovered from COVID-19
This applies to arrivals from EU Schengen Area, Canada, Japan and United States
  • Travellers who have recovered from COVID-19 in the last 6 months are exempt from providing a negative COVID-19 test (certificate needed)
  • Travellers issued with the EU Digital COVID Certificate are exempt from quarantine and COVID-19 testing
This applies to arrivals from EU Schengen Area
  • Passenger Locator Form (PLF) required
This doesn’t apply to citizens and permanent residents of San Marino and Vatican

Show less

Rules to follow in Italy

1.5m

Mandatory

Mandatory

Considerations leaving from United Kingdom

The official advice is to avoid non-essential international travel to high risk countries

Frequently Asked Questions


Yes, but conditions apply when entering Italy from United Kingdom.

Explore options for future travel

Domestic travel is not restricted, but some conditions may apply

  • Face masks are mandatory
  • There is a social distancing requirement of 1.5 metres
  • Observe COVID-19 safety rules
  • Nationwide control measures in place
  • Inter-regional travel is permitted

Explore travel options

The national COVID-19 helpline number in Sicily is 1500.

Wearing a face mask on public transport in Sicily is mandatory.

The social distance requirement in Sicily is 1.5 metres.

Make yourself known to an official member of staff and/or call the national coronavirus helpline number on 1500.

No, but conditions apply when returning to United Kingdom from Italy.

See options for return travel.

Last updated: 29 Jul 2021
Exceptions may apply, for full details: European Union.

We're working around the clock to bring you the latest COVID-19 travel updates.
This information is compiled from official sources. To the best of our knowledge, it is correct as of the last update.
Visit Rome2rio travel advice for general help.

Questions & Answers

The cheapest way to get from Holyhead to Sicily is to train and fly which costs £65 - £270 and takes 11h 46m.

More details

The fastest way to get from Holyhead to Sicily is to train and fly which takes 10h 10m and costs £150 - £600.

More details

The distance between Holyhead and Sicily is 2267 km.

The best way to get from Holyhead to Sicily without a car is to train and bus and ferry which takes 2 days 4h and costs £210 - £550.

More details

It takes approximately 10h 33m to get from Holyhead to Sicily, including transfers.

More details

The quickest flight from Manchester Airport to Catania Airport is the direct flight which takes 3h 25m.

Search flights

Sicily is 1h ahead of Holyhead. It is currently 10:40 PM in Holyhead and 11:40 PM in Sicily.

Jet2.com, Transavia Holland, Air France and seven other airlines offer flights from Manchester Airport to Catania Airport.

Search flights

There are 42+ hotels available in Sicily. Prices start at €87 per night.

More details

Map of how to get from Holyhead to Sicily.
Launch map view
  • Distance: 2267 km
  • Duration: 10h 33m

What companies run services between Holyhead, Wales and Sicily, Italy?

There is no direct connection from Holyhead to Sicily. However, you can take the train to Chester, take the train to Manchester Airport, take the walk to Manchester airport, fly to Catania, take the walk to Catania Airport, then take the bus to Catania. Alternatively, you can take the train to Chester, take the train to Manchester Airport, take the walk to Manchester airport, fly to Palermo, take the walk to Punta Raisi, then take the train to Palermo.

Airlines
Ryanair
Website
ryanair.com
Flights from Manchester to Catania via Milan Malpensa
Ave. Duration
5h 5m
When
Monday and Friday
Estimated price
€30 - €170
Flights from Manchester to Catania via Naples
Ave. Duration
5h 10m
When
Sunday
Estimated price
€30 - €170
Flights from Manchester to Catania via Eindhoven
Ave. Duration
5h 45m
When
Monday and Friday
Estimated price
€30 - €170
Flights from Manchester to Catania via Milan Bergamo
Ave. Duration
7h 15m
When
Monday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
€30 - €170
Flights from Manchester to Palermo
Ave. Duration
3h 5m
When
Monday and Friday
Estimated price
€29 - €170
Flights from Manchester to Palermo via Milan Malpensa
Ave. Duration
5h 35m
When
Monday and Friday
Estimated price
€29 - €170
Flights from Manchester to Palermo via Krakow
Ave. Duration
6h 5m
When
Saturday
Estimated price
€35 - €190
Flights from Manchester to Palermo via Budapest
Ave. Duration
6h 45m
When
Wednesday and Sunday
Estimated price
€35 - €190
Flights from Liverpool to Catania via Rome
Ave. Duration
5h 25m
When
Monday
Estimated price
€29 - €160
Flights from Liverpool to Catania via Dublin, Marseille
Ave. Duration
8h 5m
When
Friday and Sunday
Estimated price
€30 - €180
Flights from Liverpool to Palermo via Rome
Ave. Duration
5h 10m
When
Wednesday
Estimated price
€29 - €170
Flights from London Stansted to Palermo
Ave. Duration
2h 55m
When
Every day
Estimated price
€21 - €70
Flights from London Stansted to Palermo via Milan Bergamo
Ave. Duration
4h 47m
When
Monday and Thursday
Estimated price
€21 - €70
Flights from London Stansted to Palermo via Milan Malpensa
Ave. Duration
5h 37m
When
Every day
Estimated price
€21 - €70
Flights from London Stansted to Palermo via Pisa
Ave. Duration
4h 50m
When
Friday
Estimated price
€21 - €70
Flights from London Stansted to Palermo via Turin
Ave. Duration
5h 40m
When
Monday, Tuesday, Thursday, Friday and Sunday
Estimated price
€21 - €70
Flights from London Stansted to Palermo via Bologna
Ave. Duration
6h 7m
When
Friday, Saturday and Sunday
Estimated price
€21 - €70
Flights from London Stansted to Palermo via Perugia
Ave. Duration
5h 50m
When
Tuesday
Estimated price
€21 - €70
Flights from London Stansted to Palermo via Krakow
Ave. Duration
6h 15m
When
Tuesday and Saturday
Estimated price
€21 - €70
Flights from London Stansted to Palermo via Venice
Ave. Duration
6h 50m
When
Monday, Tuesday, Wednesday, Friday, Saturday and Sunday
Estimated price
€21 - €70
Flights from Bristol to Catania via Turin
Ave. Duration
6h 15m
When
Friday
Estimated price
€28 - €160
Flights from Bristol to Catania via Milan Malpensa
Ave. Duration
6h 45m
When
Wednesday, Friday and Sunday
Estimated price
€28 - €160
Flights from Liverpool to Comiso via Alicante, Milan Malpensa
Ave. Duration
10h 40m
When
Monday and Friday
Estimated price
€50 - €250
Flights from Liverpool to Comiso via Belfast (Aldergrove), Milan Bergamo
Ave. Duration
10h 10m
When
Wednesday
Estimated price
€40 - €220
Alitalia
Website
alitalia.com
Flights from Liverpool to Catania via Rome
Ave. Duration
5h
When
Tuesday, Thursday and Saturday
Estimated price
€45 - €270
Flights from Liverpool to Palermo via Rome
Ave. Duration
4h 50m
When
Tuesday, Thursday and Saturday
Estimated price
€45 - €270
Flights from Liverpool to Palermo via Malta
Ave. Duration
6h 30m
When
Sunday
Estimated price
€120 - €390
Flights from London Heathrow to Catania via Rome
Ave. Duration
5h 22m
When
Every day
Estimated price
€70 - €470
Flights from Liverpool to Comiso via Rome
Ave. Duration
7h 12m
When
Monday, Tuesday, Wednesday, Thursday, Saturday and Sunday
Estimated price
€45 - €260
Flights from Liverpool to Comiso via Amsterdam Schiphol, Milan Linate
Ave. Duration
8h 20m
When
Monday
Estimated price
€140 - €500
KLM
Website
klm.com
Flights from Manchester to Catania via Amsterdam Schiphol
Ave. Duration
6h 32m
When
Tuesday, Friday, Saturday and Sunday
Estimated price
€140 - €470
Flights from Liverpool to Catania via Rome
Ave. Duration
5h
When
Tuesday, Thursday and Saturday
Estimated price
€45 - €270
Flights from Liverpool to Palermo via Rome
Ave. Duration
4h 50m
When
Tuesday, Thursday and Saturday
Estimated price
€45 - €270
Flights from London Heathrow to Catania via Amsterdam Schiphol
Ave. Duration
5h 45m
When
Saturday
Estimated price
€120 - €460
Flights from Bristol to Catania via Amsterdam Schiphol
Ave. Duration
5h 5m
When
Tuesday, Friday, Saturday and Sunday
Estimated price
€160 - €480
easyJet
Website
easyjet.com
Flights from Manchester to Catania
Ave. Duration
3h 25m
When
Wednesday and Sunday
Estimated price
€110 - €360
Flights from Manchester to Catania via Milan Malpensa
Ave. Duration
4h 50m
When
Monday, Thursday, Friday, Saturday and Sunday
Estimated price
€110 - €360
Flights from Bristol to Catania
Ave. Duration
3h 10m
When
Monday
Estimated price
€100 - €340
Flights from Bristol to Catania via Lyon
Ave. Duration
5h 5m
When
Thursday
Estimated price
€100 - €340
Flights from Bristol to Catania via Milan Malpensa
Ave. Duration
5h 10m
When
Wednesday
Estimated price
€100 - €340
British Airways
Website
britishairways.com
Flights from Manchester to Catania via London Heathrow
Ave. Duration
6h 22m
When
Monday, Wednesday, Thursday and Sunday
Estimated price
€120 - €500
Flights from London Heathrow to Catania
Ave. Duration
3h 11m
When
Monday, Tuesday, Wednesday, Thursday, Saturday and Sunday
Estimated price
€120 - €490
Wizz Air
Website
wizzair.com
Flights from Liverpool to Catania via Iasi
Ave. Duration
9h 25m
When
Tuesday and Saturday
Estimated price
€75 - €390
Flights from Liverpool to Catania via Katowice
Ave. Duration
9h 45m
When
Wednesday
Estimated price
€60 - €330
Flights from Liverpool to Catania via Vienna
Ave. Duration
5h 20m
When
Tuesday and Saturday
Estimated price
€30 - €180
Volotea
Website
volotea.com
Flights from Liverpool to Catania via Bari
Ave. Duration
5h 5m
When
Tuesday and Saturday
Estimated price
€30 - €170
Flights from Liverpool to Palermo via Malaga
Ave. Duration
6h 40m
When
Monday
Estimated price
€35 - €200
Flights from Liverpool to Palermo via Ibiza
Ave. Duration
7h 25m
When
Friday
Estimated price
€30 - €180
Air Malta
Website
airmalta.com
Flights from Liverpool to Palermo via Rome
Ave. Duration
4h 50m
When
Tuesday, Thursday and Saturday
Estimated price
€45 - €270
Flights from Liverpool to Palermo via Malta
Ave. Duration
6h 30m
When
Sunday
Estimated price
€120 - €390
Flights from London Heathrow to Catania via Malta
Ave. Duration
7h 5m
When
Monday, Friday, Saturday and Sunday
Estimated price
€120 - €550
Jet2.com
Website
jet2.com
Flights from Manchester to Catania
Ave. Duration
3h 30m
When
Saturday
Estimated price
€110 - €300
Flights from Bristol to Catania
Ave. Duration
3h 15m
When
Tuesday
Estimated price
€110 - €290
Air France
Website
airfrance.com
Flights from Manchester to Catania via Paris CDG
Ave. Duration
5h 25m
When
Every day
Estimated price
€160 - €550
Flights from London Heathrow to Catania via Paris CDG
Ave. Duration
7h 15m
When
Every day
Estimated price
€180 - €800
Lufthansa
Website
lufthansa.com
Flights from Manchester to Catania via Munich
Ave. Duration
6h 45m
When
Sunday
Estimated price
€160 - €800
Flights from London Heathrow to Catania via Munich
Ave. Duration
5h 5m
When
Sunday
Estimated price
€210 - €700
Swiss
Website
swiss.com
Flights from Manchester to Palermo via Zurich
Ave. Duration
4h 45m
When
Monday
Estimated price
€160 - €600
Flights from London Heathrow to Catania via Zurich
Ave. Duration
5h 5m
When
Monday, Wednesday, Friday, Saturday and Sunday
Estimated price
€150 - €380
Scandinavian Airlines
Website
flysas.com
Flights from Manchester to Catania via Copenhagen
Ave. Duration
6h 45m
When
Thursday and Sunday
Estimated price
€140 - €600
Iberia
Website
iberia.com
Flights from Manchester to Catania via Madrid
Ave. Duration
7h 30m
When
Monday
Estimated price
€150 - €410
Train operators
Transport for Wales
Website
tfw.gov.wales
Train from Holyhead to Chester
Ave. Duration
1h 59m
Frequency
Hourly
Estimated price
€50 - €75
Website
tfw.wales
Train from Chester to Manchester Airport
Ave. Duration
1h 22m
Frequency
Hourly
Estimated price
€30 - €50
Website
tfw.wales
Train from Holyhead to Crewe
Ave. Duration
2h 18m
Frequency
3 times a day
Estimated price
€60 - €85
Website
tfw.wales
Train from Crewe to Birmingham New Street
Ave. Duration
1h 56m
Frequency
6 times a week
Estimated price
€35 - €55
Website
tfw.wales
Avanti West Coast
Phone
0344 556 5650
Website
avantiwestcoast.co.uk
Train from Holyhead to Chester
Ave. Duration
1h 36m
Frequency
5 times a day
Estimated price
€35 - €130
Website
avantiwestcoast.co.uk
Anytime Day Single
€35 - €50
Anytime Day Single 1st Class
€95 - €130
Train from Holyhead to London Euston
Ave. Duration
3h 38m
Frequency
Twice daily
Estimated price
€110 - €400
Website
avantiwestcoast.co.uk
Anytime Day Single
€110 - €160
Anytime Day Single 1st Class
€300 - €400
Train from Holyhead to Crewe
Ave. Duration
1h 59m
Frequency
5 times a day
Estimated price
€45 - €160
Website
avantiwestcoast.co.uk
Anytime Day Single
€45 - €65
Anytime Day Single 1st Class
€120 - €160
Train from Crewe to Birmingham New Street
Ave. Duration
1h 2m
Frequency
Hourly
Estimated price
€26 - €95
Website
avantiwestcoast.co.uk
Anytime Day Single
€26 - €35
Anytime Day Single 1st Class
€70 - €95
London Midland
Phone
+44 121 634 2040
Email
comments@londonmidland.com
Website
londonnorthwesternrailway.co.uk
Train from Crewe to Birmingham New Street
Ave. Duration
1h 21m
Frequency
Hourly
Estimated price
€26 - €30
Website
londonnorthwesternrailway.co.uk
Advanced Single/Anytime Advance
€7 - €10
Anytime Day Single
€26 - €30
CrossCountry
Phone
0344 736 9123
Email
customer.relations@crosscountrytrains.co.uk
Website
crosscountrytrains.co.uk
Train from Crewe to Birmingham New Street
Ave. Duration
1h 9m
Frequency
Once daily
Estimated price
€40 - €150
Website
crosscountrytrains.co.uk
Anytime Day
€40 - €55
Anytime Day 1st Class
€100 - €150
Train from Birmingham New Street to Bristol Temple Meads
Ave. Duration
1h 24m
Frequency
Hourly
Estimated price
€55 - €180
Website
crosscountrytrains.co.uk
Anytime Day
€55 - €70
Anytime Day 1st Class
€120 - €180
Nightjet
Phone
+43 51717
Website
nightjet.com
Night train from Salzburg Hbf to Roma Termini
Ave. Duration
11h 8m
Frequency
Once daily
Estimated price
€70 - €100
Website
Nightjet
Trenitalia Intercity

Trenitalia’s Intercity (IC) trains are slower than the high-speed Frecce trains but are still a good way to travel between major cities and towns, with routes including Rome to Naples, Venice to Bologna and Milan to Genoa. Tickets usually open for booking 90 days ahead of travel, and you’ll need make a seat reservation before boarding. All IC trains have 1st and 2nd class carriages as well as a bar buffet car, air conditioning and power sockets. InterCity trains that run at night are called InterCity Notte (ICN).

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Roma Termini to Palermo Centrale
Ave. Duration
11h 59m
Frequency
Once daily
Estimated price
€50 - €75
Website
Trenitalia Intercity
2nd Class
€50 - €75
Bus operators
RegioJet
Phone
+420 542 42 42 42
Email
info@regiojet.cz
Website
regiojet.com
Bus from London, Victoria Green Line Station to Luxembourg, P+R Bouillon
Ave. Duration
10h 30m
Frequency
4 times a week
Estimated price
€16 - €24
Website
RegioJet
FlixBus

One of Europe’s leading bus companies, Flixbus serves 2000+ destinations in 29 countries, including Germany, France, Italy, Austria, the Netherlands and Croatia and into Scandinavia and eastern Europe, as well as some US cities. Coaches have toilets, free WiFi and power outlets, plus snacks and drinks for purchase on board. Flixbus is a good choice for the budget-conscious traveller; purchase tickets in advance for the cheapest fares (note: there is no option to reserve a seat in advance).

Rome2rio's guide to FlixBus
Contact Details
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Luxembourg, P+R Bouillon to Genoa
Ave. Duration
13h 25m
Frequency
Once daily
Estimated price
€40 - €55
Website
flixbus.co.uk
Union Ivkoni
Phone
02/989 0000
Website
union-ivkoni.com
Bus and ferry from London to Salzburg
Ave. Duration
22h 27m
Frequency
Twice a week
Estimated price
€45 - €65
Schedules at
union-ivkoni.com
Autokar Polska
Phone
48/796 473 308
Email
biuro@autokarpolska.com.pl
Website
autokarpolska.com.pl
Bus from London Victoria to Legnica
Ave. Duration
20h 26m
Frequency
4 times a week
Estimated price
€45 - €70
Schedules at
autokarpolska.com.pl
Bus from Legnica to Palermo
Ave. Duration
39h
Frequency
Twice a week
Estimated price
€65 - €95
Schedules at
autokarpolska.com.pl
Ferry operators

Want to know more about travelling around Italy

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