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There are 4 ways to get from Hilton Head Island to Great Smoky Mountains National Park by bus, train or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus, travel  •  16h 29m

  1. Take the bus from Beaufort, Sc to Winston Salem, Nc
  2. Take the bus from Winston Salem, Nc to Asheville, Nc
  3. Travel from Asheville, Nc to Great Smoky Mountains National Park

3 alternative options

Bus, train, travel  •  17h 49m

  1. Take the bus from Hwy 278 & Wild Horse to Yemassee 320
  2. Take the train from Yemassee Amtrak to Selma-Smithfield Amtrak Station
  3. Take the train from Selma-Smithfield Amtrak Station to Greensboro Amtrak Station
  4. Take the bus from Greensboro, Nc to Asheville, Nc
  5. Travel from Asheville, Nc to Great Smoky Mountains National Park

Fly from Hilton Head, travel  •  6h 8m

  1. Fly from Hilton Head (HHH) to Knoxville (TYS) HHH - TYS
  2. Travel from Knoxville to Great Smoky Mountains National Park

Bus to Savannah, fly, travel  •  9h

  1. Take the bus from Beaufort, Sc to Savannah, Ga
  2. Fly from Savannah (SAV) to Knoxville (TYS) SAV - TYS
  3. Travel from Knoxville to Great Smoky Mountains National Park

Questions & Answers

The distance between Hilton Head Island and Great Smoky Mountains National Park is 284 miles.

The best way to get from Hilton Head Island to Great Smoky Mountains National Park without a car is to bus and travel which takes 16h 29m and costs .

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It takes approximately 16h 29m to get from Hilton Head Island to Great Smoky Mountains National Park, including transfers.

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There is no direct flight from Hilton Head Airport to Knoxville Airport. The quickest flight takes 3h 48m and has one stopover.

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United Airlines and American Airlines offer flights from Hilton Head Airport to Knoxville Airport.

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There are 1737+ hotels available in Great Smoky Mountains National Park. Prices start at $128 USD per night.

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The best way to get from Hilton Head Island to Hilton Head Airport is to line 310 bus which takes 7m and costs .

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Map of how to get from Hilton Head Island to Great Smoky Mountains National Park.
Launch map view
  • Distance: 283.9 miles
  • Duration: 16h 29m

What companies run services between Hilton Head Island, SC, USA and Great Smoky Mountains National Park, TN, USA?

There is no direct connection from Hilton Head Island to Great Smoky Mountains National Park. However, you can take the bus to Lowes, take the walk to Beaufort, Sc, take the bus to Winston Salem, Nc, take the bus to Asheville, Nc, then take the travel to Great Smoky Mountains National Park. Alternatively, you can take the bus to Yemassee, take the walk to Yemassee Amtrak, take the train to Selma-Smithfield Amtrak Station, take the train to Greensboro Amtrak Station, take the walk to Greensboro, Nc, take the bus to Asheville, Nc, then take the travel to Great Smoky Mountains National Park.

Airlines
American Airlines
Website
aa.com
Flights from Hilton Head to Knoxville via Charlotte
Ave. Duration
4h 40m
When
Every day
Estimated price
$110 - $600
Flights from Hilton Head to Knoxville via Charlotte, Reagan Washington
Ave. Duration
6h 48m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$140 - $650
Flights from Hilton Head to Knoxville via Charlotte, Philadelphia
Ave. Duration
7h 25m
When
Monday to Saturday
Estimated price
$160 - $700
Flights from Hilton Head to Knoxville via Charlotte, Chicago O'Hare
Ave. Duration
7h 33m
When
Every day
Estimated price
$160 - $700
Flights from Savannah to Knoxville via Charlotte
Ave. Duration
3h 40m
When
Every day
Estimated price
$180 - $950
Flights from Savannah to Knoxville via Reagan Washington
Ave. Duration
5h 48m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$230 - $1,100
Flights from Savannah to Knoxville via Miami
Ave. Duration
6h 12m
When
Every day
Estimated price
$250 - $1,100
Delta
Website
delta.com
Flights from Savannah to Knoxville via Atlanta
Ave. Duration
3h 54m
When
Every day
Estimated price
$170 - $950
Flights from Savannah to Knoxville via Detroit
Ave. Duration
5h 25m
When
Saturday
Estimated price
$230 - $1,100
United Airlines
Website
united.com
Flights from Hilton Head to Knoxville via Washington Dulles
Ave. Duration
4h 50m
When
Every day
Estimated price
$150 - $700
Flights from Hilton Head to Knoxville via Newark
Ave. Duration
7h 11m
When
Saturday and Sunday
Estimated price
$170 - $750
Flights from Hilton Head to Knoxville via Chicago O'Hare
Ave. Duration
7h 30m
When
Sunday
Estimated price
$160 - $750
Flights from Savannah to Knoxville via Washington Dulles
Ave. Duration
4h 20m
When
Every day
Estimated price
$240 - $1,100
Flights from Savannah to Knoxville via Chicago O'Hare
Ave. Duration
6h 35m
When
Every day
Estimated price
$260 - $1,200
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Yemassee Amtrak to Selma-Smithfield Amtrak Station
Ave. Duration
4h 44m
Frequency
Once daily
Estimated price
$50 - $130
Website
amtrak.com
Coach Seat
$50 - $75
Flexi Coach Seat
$90 - $130
Business Coach Seat
$90 - $130
Room
$230 - $320
Train from Selma-Smithfield Amtrak Station to Greensboro Amtrak Station
Ave. Duration
2h 29m
Frequency
Once daily
Estimated price
$30 - $70
Website
amtrak.com
Coach Seat
$30 - $45
Flexi Coach Seat
$55 - $80
Business Coach Seat
$45 - $70
Room
$160 - $230
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Beaufort, Sc to Winston Salem, Nc
Ave. Duration
8h 45m
Frequency
3 times a day
Estimated price
$35 - $85
Website
greyhound.com
Economy
$35 - $55
Flexible
$65 - $85
Bus from Winston Salem, Nc to Asheville, Nc
Ave. Duration
2h 55m
Frequency
Once daily
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $30
Flexible
$35 - $50
Bus from Greensboro, Nc to Asheville, Nc
Ave. Duration
4h 10m
Frequency
Once daily
Estimated price
$22 - $55
Website
greyhound.com
Economy
$22 - $35
Flexible
$40 - $55
Bus from Beaufort, Sc to Savannah, Ga
Ave. Duration
55m
Frequency
Every 4 hours
Estimated price
$10 - $23
Website
greyhound.com
Economy
$10 - $15
Flexible
$18 - $23
Palmetto Breeze Transit
Website
palmettobreezetransit.com
Bus from Hwy 278 & Wild Horse to Yemassee
Ave. Duration
1h 41m
Frequency
Twice daily
Estimated price
$2
Schedules at
palmettobreezetransit.com

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