There are 7 ways to get from Henderson to San Diego by bus, plane, bus (Greyhound, Flixbus), car, train, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Line 217 bus, fly
best- Take the bus from WB Lake Mead after Boulder to South Strip Transit Terminal
- Fly from Harry Reid International Airport (LAS) to San Diego International Airport (SAN)LAS - SAN
3h 14m$52–212Bus via Santa Ana
- Take the bus from South Strip Transit Terminal to Santa Ana Bus StopGreyhound US0900
- Take the bus from Santa Ana Bus Stop to San DiegoFlixBus 2017
10h 6m$57–126Drive 329 mi
- Drive from Henderson to San Diego329 mi
5h 24m$60–87Bus, train
- Take the bus from South Strip Transit Terminal to Santa Ana Bus StopGreyhound US0900
- Take the train from Santa Ana to San DiegoPacific Surfliner
10h 19m$68–118Bus
- Take the bus from Las Vegas to San Ysidro, CALas Vegas
10h 56m$94–137Bus, train via San Bernardino
- Take the bus from Las Vegas, NV to San Bernardino
- Take the train from San Bernardino - Downtown to Santa Ana
- Take the train from Santa Ana to San Diego
11h 31m$88–117Bus #2 (Flixbus)
- Take the bus from Las Vegas Strip to San DiegoFlixBus 2037
12h 31m$59–177
Henderson to San Diego by bus
Questions & Answers
The cheapest way to get from Henderson to San Diego is to drive which costs $60 - $90 and takes 5h 24m.
The fastest way to get from Henderson to San Diego is to line 217 bus and fly which takes 3h 14m and costs $50 - $220.
No, there is no direct bus from Henderson to San Diego. However, there are services departing from WB Lake Mead after Boulder and arriving at San Diego via South Strip Transit Terminal and Santa Ana Bus Stop. The journey, including transfers, takes approximately 10h 6m.
The distance between Henderson and San Diego is 278 miles. The road distance is 330.9 miles.
The best way to get from Henderson to San Diego without a car is to bus via Santa Ana which takes 10h 6m and costs $55 - $130.
It takes approximately 3h 14m to get from Henderson to San Diego, including transfers.
Henderson to San Diego bus services, operated by Greyhound USA, depart from South Strip Transit Terminal station.
Henderson to San Diego bus services, operated by Greyhound USA, arrive at Santa Ana Bus Stop station.
Yes, the driving distance between Henderson to San Diego is 331 miles. It takes approximately 5h 24m to drive from Henderson to San Diego.
There are 2079+ hotels available in San Diego.
What companies run services between Henderson, NV, USA and San Diego, CA, USA?
You can take a bus from WB Lake Mead after Boulder to San Diego via South Strip Transit Terminal and Santa Ana Bus Stop in around 10h 6m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- southwest.com
Flights from Harry Reid International Airport to San Diego International Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $45–290
- Website
- alaskaair.com
Flights from Harry Reid International Airport to San Diego International Airport
- Ave. Duration
- 1h 21m
- When
- Every day
- Estimated price
- $45–290
- Website
- delta.com
Flights from Harry Reid International Airport to San Diego International Airport
- Ave. Duration
- 1h 17m
- When
- Every day
- Estimated price
- $45–290
- Website
- flyfrontier.com
Flights from Harry Reid International Airport to San Diego International Airport
- Ave. Duration
- 1h 20m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $45–290
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Santa Ana to San Diego
- Ave. Duration
- 2h 3m
- Frequency
- Every 2 hours
- Estimated price
- $27–32
- Website
- https://www.amtrak.com/home.html
- Phone
- (800) 371-LINK (5465)
- Website
- metrolinktrains.com
Train from San Bernardino - Downtown to Santa Ana
- Ave. Duration
- 1h 20m
- Frequency
- 3 times a day
- Estimated price
- $9–13
- Website
- https://metrolinktrains.com
- Passenger
- $9–13
- Phone
- +1 702-228-7433
- Website
- rtcsnv.com
Bus from WB Lake Mead after Boulder to South Strip Transit Terminal
- Ave. Duration
- 46 min
- Frequency
- Hourly
- Estimated price
- $6
- Website
- https://www.rtcsnv.com
- Schedules at
- https://www.rtcsnv.com/ways-to-travel/schedules-maps/
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from South Strip Transit Terminal to Santa Ana Bus Stop
- Ave. Duration
- 5h 30m
- Frequency
- Twice daily
- Estimated price
- $35–80
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Santa Ana Bus Stop to San Diego
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $16–40
- Schedules at
- flixbus.com
Bus from Las Vegas Strip to San Diego
- Ave. Duration
- 8h 40m
- Frequency
- 3 times a week
- Estimated price
- $45–150
- Schedules at
- flixbus.com
- Phone
- +1 833 766 3553
- Website
- tufesainternacional.com
Bus from Las Vegas to San Ysidro, CA
- Ave. Duration
- 7h
- Frequency
- Twice daily
- Estimated price
- $80–110
- Schedules at
- tufesainternacional.com
- Phone
- +1 866 691 9732
- eplasales@eplalimo.com
- Website
- eplalimo.com
Bus from Las Vegas, NV to San Bernardino
- Ave. Duration
- 3h 40m
- Frequency
- Once daily
- Estimated price
- $40–60
- Schedules at
- eplalimo.com
- One Way
- $40–60
Want to know more about travelling around United States
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