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How to get fromHeidelberg to Sienaby train, plane, train (Trenitalia), bus, night train or car

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There are 11 ways to get from Heidelberg to Siena by train, plane, train (Trenitalia), bus, night train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Frankfurt, fly to Florence Peretola Airport, train

    best
    1. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane plane FRA - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    7h 44m
    €127–352

  2. Bus

    cheapest
    1. Take the bus from Heidelberg Post Waypoint to Karlsruhe central train stationbus bus N94 / ...
    2. Take the bus from Karlsruhe central train station to Florence Villa Constanza Bus Stationbus bus N77
    3. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 443 / ...
    17h 33m
    €78–123

  3. Train

    1. Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain train 20 / ...
    2. Take the train from Basel SBB to Luganotrain train Ec
    3. Take the train from Lugano to Milano Centraletrain train
    4. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    5. Take the train from Firenze S.M.N. to Sienatrain train Re
    13h 52m
    €112–410

  4. Bus, train

    1. Take the bus from Ludwigshafen to Veronabus bus
    2. Take the train from Verona Porta Nuova to Florence Santa Maria Novellatrain train
    3. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131
    13h 56m

  5. Train, night train, bus

    1. Take the train from Heidelberg, Hauptbahnhof to Hauptbahnhoftrain train 62 / ...
    2. Take the night train from Stuttgart Hbf to Venezia Mestrenighttrain night train Nj
    3. Take the train from Venezia Mestre to Firenze S.M.N.train train Fr
    4. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131
    17h 59m

  6. Train to Stuttgart Airport, fly to Florence Peretola Airport, train

    1. Take the train from Heidelberg, Hauptbahnhof to Hauptbahnhoftrain train
    2. Fly from Stuttgart Airport (STR) to Florence Peretola Airport (FLR)plane plane STR - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    9h 4m
    €138–316

  7. Train to Frankfurt, fly to Bologna Guglielmo Marconi Airport, train

    1. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane plane FRA - BLQ
    3. Take the train from Bologna Centrale to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    8h 9m
    €139–390

  8. Train, train to Munich International Airport, fly to Florence Peretola Airport

    1. Take the train from Heidelberg, Hauptbahnhof to Hauptbahnhoftrain train
    2. Take the train from Hauptbahnhof to Pasingtrain train
    3. Take the train from Pasing to Flughafen Münchentrain train
    4. Fly from Munich International Airport (MUC) to Florence Peretola Airport (FLR)plane plane MUC - FLR
    5. Take the train from Firenze S.M.N. to Sienatrain train
    10h 37m
    €145–370

  9. Train, train to Zurich Airport, fly to Florence Peretola Airport

    1. Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain train
    2. Take the train from Basel SBB to Zürich HBtrain train
    3. Fly from Zurich Airport (ZRH) to Florence Peretola Airport (FLR)plane plane ZRH - FLR
    4. Take the train from Firenze S.M.N. to Sienatrain train
    10h 37m
    €148–451

  10. Train to Frankfurt, fly to Venice Marco Polo Airport, train

    1. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Venice Marco Polo Airport (VCE)plane plane FRA - VCE
    3. Take the train from Venezia Mestre to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    10h 16m
    €137–385

  11. Drive 940.8 km

    1. Drive from Heidelberg to Sienacar car 940.8 km
    9h 10m
    €144–207

Heidelberg to Siena by train

Calendar76Weekly Trains
Duration13h 52mAverage Duration
Ticket€112Cheapest Price
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Questions & Answers

What companies run services between Heidelberg, Germany and Siena, Italy?

You can take a train from Heidelberg, Hauptbahnhof to Siena via Mannheim, Hauptbahnhof, Basel SBB, Lugano, Milano Centrale, and Firenze S.M.N. in around 13h 52m. Alternatively, you can take a bus from Heidelberg Post Waypoint to Siena via Karlsruhe central train station and Florence Villa Constanza Bus Station in around 17h 33m.

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