There are 11 ways to get from Heidelberg to Siena by train, plane, train (Trenitalia), bus, night train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Frankfurt, fly to Florence Peretola Airport, train
best- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane FRA - FLR
- Take the train from Firenze S.M.N. to Sienatrain
7h 44m€127–332Train, bus
cheapest- Take the train from Kirchheim/Rohrbach, Bf to Karlsruhe Hauptbahnhoftrain S3 / ...
- Take the bus from Karlsruhe Central Bus Station to Milanbus
- Take the bus from Milan to Siena Central Train Stationbus
19h 10m€55–136Train
- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 20 / ...
- Take the train from Basel SBB to Luganotrain Ec
- Take the train from Lugano to Milano Centraletrain
- Take the train from Milano Centrale to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
13h 51m€111–410Bus
- Take the bus from Heidelberg Post Waypoint to Karlsruhe central train stationbus 108 / ...
- Take the bus from Karlsruhe central train station to Florence Villa Constanza Bus Stationbus N77
- Take the bus from Florence Villa Constanza Bus Station to Sienabus 443 / ...
17h 31m€78–123Train, night train, bus
- Take the train from Heidelberg, Hauptbahnhof to Hauptbahnhoftrain 62 / ...
- Take the night train from Stuttgart Hbf to Venezia Mestrenighttrain Nj
- Take the train from Venezia Mestre to Firenze S.M.N.train Fr
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131
17h 59mTrain to Stuttgart Airport, fly to Florence Peretola Airport, train
- Take the train from Heidelberg, Hauptbahnhof to Hauptbahnhoftrain
- Fly from Stuttgart Airport (STR) to Florence Peretola Airport (FLR)plane STR - FLR
- Take the train from Firenze S.M.N. to Sienatrain
9h 4m€133–306Train to Frankfurt, fly to Bologna Guglielmo Marconi Airport, train
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane FRA - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
8h 9m€139–390Train, train to Munich International Airport, fly to Florence Peretola Airport
- Take the train from Heidelberg, Hauptbahnhof to Hauptbahnhoftrain
- Take the train from Hauptbahnhof to Pasingtrain
- Take the train from Pasing to Flughafen Münchentrain
- Fly from Munich International Airport (MUC) to Florence Peretola Airport (FLR)plane MUC - FLR
- Take the train from Firenze S.M.N. to Sienatrain
10h 37m€149–370Train, train to Zurich Airport, fly to Florence Peretola Airport
- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain
- Take the train from Basel SBB to Zürich HBtrain
- Fly from Zurich Airport (ZRH) to Florence Peretola Airport (FLR)plane ZRH - FLR
- Take the train from Firenze S.M.N. to Sienatrain
10h 37m€147–451Train to Frankfurt, fly to Venice Marco Polo Airport, train
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Venice Marco Polo Airport (VCE)plane FRA - VCE
- Take the train from Venezia Mestre to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
10h 16m€142–375Drive 940.8 km
- Drive from Heidelberg to Sienacar 940.8 km
9h 10m€144–207
Heidelberg to Siena by train
Questions & Answers
The cheapest way to get from Heidelberg to Siena is to train and bus which costs €55 - €140 and takes 19h 10m.
The fastest way to get from Heidelberg to Siena is to train and fly which takes 7h 44m and costs €120 - €340.
No, there is no direct bus from Heidelberg to Siena. However, there are services departing from Heidelberg Post Waypoint and arriving at Siena via Karlsruhe central train station and Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 17h 31m.
No, there is no direct train from Heidelberg to Siena. However, there are services departing from Heidelberg, Hauptbahnhof and arriving at Siena via Mannheim, Hauptbahnhof, Basel SBB, Lugano, Milano Centrale and Firenze S.M.N.. The journey, including transfers, takes approximately 13h 51m.
The distance between Heidelberg and Siena is 910 km. The road distance is 940.8 km.
The best way to get from Heidelberg to Siena without a car is to train which takes 13h 51m and costs €110 - €410.
It takes approximately 7h 44m to get from Heidelberg to Siena, including transfers.
Heidelberg to Siena bus services, operated by FlixBus, depart from Heidelberg Post Waypoint station.
Heidelberg to Siena train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mannheim, Hauptbahnhof station.
The best way to get from Heidelberg to Siena is to train which takes 13h 51m and costs €110 - €410. Alternatively, you can bus, which costs €75 - €130 and takes 17h 31m.
What companies run services between Heidelberg, Germany and Siena, Italy?
You can take a train from Heidelberg, Hauptbahnhof to Siena via Mannheim, Hauptbahnhof, Basel SBB, Lugano, Milano Centrale, and Firenze S.M.N. in around 13h 51m. Alternatively, you can take a bus from Heidelberg Post Waypoint to Siena via Karlsruhe central train station and Florence Villa Constanza Bus Station in around 17h 31m.
- Website
- lufthansa.com
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- €90–350
Flights from Frankfurt to Florence Peretola Airport via Munich International Airport
- Ave. Duration
- 3h 18m
- When
- Every day
- Estimated price
- €100–350
Flights from Stuttgart Airport to Florence Peretola Airport via Munich International Airport
- Ave. Duration
- 3h 13m
- When
- Every day
- Estimated price
- €140–450
Flights from Stuttgart Airport to Florence Peretola Airport via Frankfurt
- Ave. Duration
- 3h 56m
- When
- Every day
- Estimated price
- €100–470
Flights from Frankfurt to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- €90–330
Flights from Frankfurt to Bologna Guglielmo Marconi Airport via Munich International Airport
- Ave. Duration
- 3h 16m
- When
- Every day
- Estimated price
- €100–330
Flights from Munich International Airport to Florence Peretola Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- €110–390
Flights from Zurich Airport to Florence Peretola Airport via Munich International Airport
- Ave. Duration
- 3h 5m
- When
- Every day
- Estimated price
- €110–370
Flights from Frankfurt to Venice Marco Polo Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €85–270
Flights from Frankfurt to Venice Marco Polo Airport via Munich International Airport
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- €95–320
- Website
- ita-airways.com
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- €90–350
Flights from Stuttgart Airport to Florence Peretola Airport via Zurich Airport
- Ave. Duration
- 3h 15m
- When
- Wednesday
- Estimated price
- €100–210
Flights from Stuttgart Airport to Florence Peretola Airport via Frankfurt
- Ave. Duration
- 4h 15m
- When
- Monday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €150–470
Flights from Stuttgart Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 4h 45m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €140–250
Flights from Frankfurt to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- €90–330
Flights from Munich International Airport to Florence Peretola Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- €110–390
Flights from Zurich Airport to Florence Peretola Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- €75–210
Flights from Frankfurt to Venice Marco Polo Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €85–270
- Website
- airdolomiti.it
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €100–350
Flights from Frankfurt to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- €100–330
Flights from Munich International Airport to Florence Peretola Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- €110–390
Flights from Zurich Airport to Florence Peretola Airport via Munich International Airport
- Ave. Duration
- 3h 10m
- When
- Tuesday, Wednesday, Thursday, and Saturday
- Estimated price
- €110–370
- Website
- swiss.com
Flights from Frankfurt to Florence Peretola Airport via Zurich Airport
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- €120–270
Flights from Stuttgart Airport to Florence Peretola Airport via Zurich Airport
- Ave. Duration
- 3h 20m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €100–210
Flights from Zurich Airport to Florence Peretola Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- €75–210
- Website
- condor.com
Flights from Frankfurt to Venice Marco Polo Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €60–240
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- €18–28
- Website
- https://int.bahn.de/en
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 21m
- Frequency
- Hourly
- Estimated price
- €27–65
- Website
- https://int.bahn.de/en
Train from Heidelberg, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 39 min
- Frequency
- Hourly
- Estimated price
- €18–45
- Website
- https://int.bahn.de/en
Train from Hauptbahnhof to Pasing
- Ave. Duration
- 2h 37m
- Frequency
- Hourly
- Estimated price
- €18–60
- Website
- https://int.bahn.de/en
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Once daily
- Estimated price
- €12–40
- Website
- https://www.ns.nl/en
- 2nd Class
- €12–19
- 1st Class
- €23–40
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 50m
- Frequency
- Once daily
- Estimated price
- €40–140
- Website
- https://www.ns.nl/en
- 2nd Class
- €40–60
- 1st Class
- €80–140
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11
- Website
- https://www.trenitalia.com/en.html
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- Twice daily
- Estimated price
- €9–10
- Website
- https://www.trenitalia.com/en.html
- Phone
- +43 5 1717
- Website
- oebb.at
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 59m
- Frequency
- Once daily
- Estimated price
- €93
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Basel SBB to Lugano
- Ave. Duration
- 2h 54m
- Frequency
- Every 3 hours
- Estimated price
- €55–110
- Website
- https://www.sbb.ch/en
Train from Lugano to Milano Centrale
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €23–45
- Website
- https://www.sbb.ch/en
Train from Basel SBB to Zürich HB
- Ave. Duration
- 1h 13m
- Frequency
- Every 20 minutes
- Estimated price
- €22–40
- Website
- https://www.sbb.ch/en
- Phone
- +49 (0) 7531 915109
- info@sbb-deutschland.de
- Website
- sbb-deutschland.de
Train from Basel SBB to Lugano
- Ave. Duration
- 3h 21m
- Frequency
- Once daily
- Estimated price
- €20–25
- Schedules at
- sbb-deutschland.de
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 54m
- Frequency
- Hourly
- Estimated price
- €30–85
- Schedules at
- trenitalia.com
Train from Venezia Mestre to Firenze S.M.N.
- Ave. Duration
- 2h 1m
- Frequency
- Hourly
- Estimated price
- €30–60
- Schedules at
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €15–35
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 3h 42m
- Frequency
- Once daily
- Estimated price
- €23–65
- Website
- https://www.trenitalia.com/en.html
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Once daily
- Estimated price
- €9–15
- Website
- https://www.trenitalia.com/en.html
- Phone
- +43 51717
- Website
- nightjet.com
Night train from Stuttgart Hbf to Venezia Mestre
- Ave. Duration
- 11h 54m
- Frequency
- Once daily
- Estimated price
- €65–270
- Website
- https://www.nightjet.com/en/#/home
- Sleeper Carriage
- €260–270
- Couchette Carriage
- €150–180
- Seating Carriage
- €65–80
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Venezia Mestre to Firenze S.M.N.
- Ave. Duration
- 2h 11m
- Frequency
- Once a week
- Estimated price
- €26–60
- Website
- https://www.italotreno.it/en
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 46 min
- Frequency
- Once a week
- Estimated price
- €13–35
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 59 min
- Frequency
- Once a week
- Estimated price
- €27–70
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €45–70
- 2nd Class
- €27–40
- Phone
- +43 1 89900
- meinenachricht@westbahn.at
- Website
- westbahn.at
Train from Hauptbahnhof to Pasing
- Ave. Duration
- 2h 14m
- Frequency
- Twice daily
- Estimated price
- €19–60
- Website
- https://westbahn.at/en/
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Pasing to Flughafen München
- Ave. Duration
- 52 min
- Frequency
- Every 20 minutes
- Estimated price
- €10–15
- Website
- https://int.bahn.de/en
Train from Kirchheim/Rohrbach, Bf to Karlsruhe Hauptbahnhof
- Ave. Duration
- 45 min
- Frequency
- Every 30 minutes
- Estimated price
- €11–16
- Website
- https://int.bahn.de/en
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Heidelberg Post Waypoint to Karlsruhe central train station
- Ave. Duration
- 44 min
- Frequency
- Hourly
- Estimated price
- €7–10
- Website
- https://www.flixbus.co.uk
Bus from Karlsruhe central train station to Florence Villa Constanza Bus Station
- Ave. Duration
- 14h 15m
- Frequency
- Once daily
- Estimated price
- €65–95
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 50 min
- Frequency
- Every 2 hours
- Estimated price
- €11–14
- Website
- https://www.flixbus.co.uk
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 55 min
- Frequency
- 5 times a day
- Estimated price
- €6–18
- Website
- https://www.itabus.it/en/home
Bus from Milan to Siena Central Train Station
- Ave. Duration
- 5h 15m
- Frequency
- Twice daily
- Estimated price
- €9–35
- Website
- https://www.itabus.it/en/home
- Phone
- +39 080 3112335
- info@marinobus.it
- Website
- marinobus.it
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- €7–14
- Website
- https://marinobus.it/en/
Bus from Karlsruhe Central Bus Station to Milan
- Ave. Duration
- 11h 10m
- Frequency
- Twice a week
- Estimated price
- €35–85
- Website
- https://marinobus.it/en/
- Phone
- +39 055 849 0505
- servizioclienti@at-bus.it
- Website
- at-bus.it
Bus from Firenze Autostazione to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Website
- https://www.at-bus.it/en
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More Questions & Answers
Heidelberg to Siena bus services, operated by FlixBus, arrive at Karlsruhe central train station.
Heidelberg to Siena train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Basel SBB station.
Yes, the driving distance between Heidelberg to Siena is 941 km. It takes approximately 9h 10m to drive from Heidelberg to Siena.
Book your Heidelberg to Siena train tickets online with Omio.
Book your Heidelberg to Siena bus tickets online with FlixBus.
There are 2291+ hotels available in Siena.











































































