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How to get fromHeidelberg to Sienaby train, plane, train (Trenitalia), bus, night train or car

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There are 10 ways to get from Heidelberg to Siena by train, plane, train (Trenitalia), bus, night train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Frankfurt, fly to Florence Peretola Airport, train

    best
    1. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane plane FRA - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    7h 43m
    €128–354

  2. Bus

    cheapest
    1. Take the bus from Heidelberg Post Waypoint to Karlsruhe central train stationbus bus N94 / ...
    2. Take the bus from Karlsruhe central train station to Florence Villa Constanza Bus Stationbus bus N77
    3. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 443 / ...
    17h 49m
    €62–114

  3. Train

    1. Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain train 20 / ...
    2. Take the train from Basel SBB to Luganotrain train Ec
    3. Take the train from Lugano to Milano Centraletrain train
    4. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    5. Take the train from Firenze S.M.N. to Sienatrain train Re
    13h 51m
    €127–327

  4. Train, night train, bus

    1. Take the train from Heidelberg, Hauptbahnhof to Hauptbahnhoftrain train 62 / ...
    2. Take the night train from Stuttgart Hbf to Venezia S. Lucianighttrain night train Nj
    3. Take the train from Venezia S. Lucia to Firenze S.M.N.train train Fr
    4. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131
    18h 26m

  5. Train to Stuttgart Airport, fly to Florence Peretola Airport, train

    1. Take the train from Heidelberg, Hauptbahnhof to Hauptbahnhoftrain train
    2. Fly from Stuttgart Airport (STR) to Florence Peretola Airport (FLR)plane plane STR - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    9h 3m
    €145–305

  6. Train to Frankfurt, fly to Bologna Guglielmo Marconi Airport, train

    1. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane plane FRA - BLQ
    3. Take the train from Bologna Centrale to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    8h 21m
    €132–412

  7. Train, train to Munich International Airport, fly to Florence Peretola Airport

    1. Take the train from Heidelberg, Hauptbahnhof to Hauptbahnhoftrain train
    2. Take the train from Hauptbahnhof to München Hbftrain train
    3. Fly from Munich International Airport (MUC) to Florence Peretola Airport (FLR)plane plane MUC - FLR
    4. Take the train from Firenze S.M.N. to Sienatrain train
    10h 21m
    €172–438

  8. Train, train to Zurich Airport, fly to Florence Peretola Airport

    1. Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain train
    2. Take the train from Basel SBB to Zürich HBtrain train
    3. Fly from Zurich Airport (ZRH) to Florence Peretola Airport (FLR)plane plane ZRH - FLR
    4. Take the train from Firenze S.M.N. to Sienatrain train
    10h 37m
    €174–488

  9. Train, bus

    1. Take the train from Mannheim Hbf to Zuerich Hbtrain train Ec
    2. Take the train from Zürich HB to Cadenazzotrain train
    3. Take the train from Cadenazzo to Milano Centraletrain train
    4. Take the train from Milano Centrale to Florence Santa Maria Novellatrain train
    5. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131
    17h 42m

  10. Drive 940.8 km

    1. Drive from Heidelberg to Sienacar car 940.8 km
    9h 10m
    €146–211

Heidelberg to Siena by train

Calendar76Weekly Trains
Duration13h 51mAverage Duration
Ticket€127Cheapest Price
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Questions & Answers

What companies run services between Heidelberg, Germany and Siena, Italy?

You can take a train from Heidelberg, Hauptbahnhof to Siena via Mannheim, Hauptbahnhof, Basel SBB, Lugano, Milano Centrale, and Firenze S.M.N. in around 13h 51m. Alternatively, you can take a bus from Heidelberg Post Waypoint to Siena via Karlsruhe central train station and Florence Villa Constanza Bus Station in around 17h 49m.

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