There are 13 ways to get from Heidelberg to Assisi by train (Trenitalia), bus, train, night train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 20 / ...
- Take the train from Basel SBB to Luganotrain Ec
- Take the train from Lugano to Milano Porta Garibalditrain S11
- Take the train from Milano P.Garibaldi to Perugiatrain Fr
16h 8m€103–362Train to Frankfurt, fly to Fiumicino International Airport, train
cheapest- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Fiumicino International Airport (FCO)plane FRA - FCO
- Take the train from Roma Termini to Folignotrain
10h 38m€75–264Bus via Florence
- Take the bus from Heidelberg Post Waypoint to Karlsruhe central train stationbus 108 / ...
- Take the bus from Karlsruhe central train station to Florence Villa Constanza Bus Stationbus N77
- Take the bus from Florence Villa Constanza Bus Station to Assisibus 529
19h 34m€81–119Train, night train
- Take the train from Heidelberg, Hauptbahnhof to Hauptbahnhoftrain 62 / ...
- Take the night train from Stuttgart Hbf to Venezia Mestrenighttrain Nj
- Take the train from Venezia Mestre to Folignotrain Ic
22h 24m€117–376Drive 1,046 km
- Drive from Heidelberg to Assisicar 1,046 km
10h 7m€161–232Train via Florence
- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 20 / ...
- Take the train from Basel SBB to Chiassotrain Ec
- Take the train from Chiasso to Firenze S.M.N.train Ec
- Take the train from Firenze S.M.N. to Assisitrain
17h 34m€141–428Bus
- Take the bus from Ludwigshafen to Riminibus
- Take the bus from Rimini - Via Annibale Fada to Assisi - S.M. Angeli - fermata Hotel Antonellibus Rimini
19h 39m€87–109Train to Frankfurt, fly to Florence Peretola Airport, train
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane FRA - FLR
- Take the train from Firenze S.M.N. to Assisitrain
10h 9m€132–348Train to Stuttgart Airport, fly to Fiumicino International Airport, train
- Take the train from Heidelberg, Hauptbahnhof to Hauptbahnhoftrain
- Fly from Stuttgart Airport (STR) to Fiumicino International Airport (FCO)plane STR - FCO
- Take the train from Roma Termini to Folignotrain
10h 17m€106–305Train to Frankfurt, fly to Bologna Guglielmo Marconi Airport, train
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane FRA - BLQ
- Take the train from Bologna Centrale to Florence Santa Maria Novellatrain
- Take the train from Firenze S.M.N. to Assisitrain
10h 45m€150–390Train to Frankfurt, fly to Milan Linate Airport, train
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Milan Linate Airport (LIN)plane FRA - LIN
- Take the train from Milano P.Garibaldi to Perugiatrain
11h 21m€99–279Train, train to Zurich Airport, fly to Florence Peretola Airport
- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain
- Take the train from Basel SBB to Zürich HBtrain
- Fly from Zurich Airport (ZRH) to Florence Peretola Airport (FLR)plane ZRH - FLR
- Take the train from Firenze S.M.N. to Assisitrain
13h 2m€151–467Train to Frankfurt, fly to Venice Marco Polo Airport, train
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Venice Marco Polo Airport (VCE)plane FRA - VCE
- Take the train from Venezia Mestre to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Assisitrain
12h 41m€142–391
Heidelberg to Assisi by train and bus
Questions & Answers
The cheapest way to get from Heidelberg to Assisi is to bus which costs €85 - €110 and takes 19h 39m.
The fastest way to get from Heidelberg to Assisi is to drive which takes 10h 7m and costs €160 - €240.
No, there is no direct bus from Heidelberg to Assisi. However, there are services departing from Heidelberg Post Waypoint and arriving at Assisi via Karlsruhe central train station and Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 19h 34m.
The distance between Heidelberg and Assisi is 1077 km. The road distance is 1046 km.
The best way to get from Heidelberg to Assisi without a car is to train which takes 16h 8m and costs €100 - €370.
It takes approximately 16h 8m to get from Heidelberg to Assisi, including transfers.
Heidelberg to Assisi bus services, operated by FlixBus, depart from Heidelberg Post Waypoint station.
The best way to get from Heidelberg to Assisi is to train which takes 16h 8m and costs €100 - €370. Alternatively, you can bus via Florence, which costs €80 - €120 and takes 19h 34m.
Heidelberg to Assisi bus services, operated by FlixBus, arrive at Karlsruhe central train station.
Yes, the driving distance between Heidelberg to Assisi is 1046 km. It takes approximately 10h 7m to drive from Heidelberg to Assisi.
What companies run services between Heidelberg, Germany and Assisi, Italy?
You can take a train from Heidelberg, Hauptbahnhof to P.za Matteotti Assisi via Mannheim, Hauptbahnhof, Basel SBB, Lugano, Milano P.Garibaldi, Perugia, and Fontivegge - Perugia in around 16h 8m. Alternatively, you can take a bus from Heidelberg Post Waypoint to Assisi via Karlsruhe central train station and Florence Villa Constanza Bus Station in around 19h 34m.
- Website
- lufthansa.com
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- €90–320
Flights from Frankfurt to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 18m
- When
- Every day
- Estimated price
- €110–320
Flights from Stuttgart Airport to Fiumicino International Airport via Munich
- Ave. Duration
- 3h 55m
- When
- Monday to Saturday
- Estimated price
- €75–300
Flights from Frankfurt to Fiumicino International Airport
- Ave. Duration
- 1h 52m
- When
- Every day
- Estimated price
- €60–360
Flights from Frankfurt to Fiumicino International Airport via Munich
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- €40–260
Flights from Frankfurt to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- €90–300
Flights from Frankfurt to Bologna Guglielmo Marconi Airport via Munich
- Ave. Duration
- 3h 16m
- When
- Every day
- Estimated price
- €100–310
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €60–150
Flights from Frankfurt to Milan Linate Airport via Munich
- Ave. Duration
- 3h 20m
- When
- Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €65–150
Flights from Zurich Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 5m
- When
- Every day
- Estimated price
- €110–350
Flights from Frankfurt to Venice Marco Polo Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €85–270
Flights from Frankfurt to Venice Marco Polo Airport via Munich
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- €90–300
- Website
- ita-airways.com
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- €90–320
Flights from Stuttgart Airport to Fiumicino International Airport
- Ave. Duration
- 1h 40m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- €70–180
Flights from Stuttgart Airport to Fiumicino International Airport via Milan Linate Airport
- Ave. Duration
- 3h 50m
- When
- Monday to Friday
- Estimated price
- €55–200
Flights from Frankfurt to Fiumicino International Airport
- Ave. Duration
- 1h 52m
- When
- Every day
- Estimated price
- €60–360
Flights from Frankfurt to Fiumicino International Airport via Milan Linate Airport
- Ave. Duration
- 3h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €70–180
Flights from Frankfurt to Fiumicino International Airport via Venice Marco Polo Airport
- Ave. Duration
- 3h 30m
- When
- Thursday to Sunday
- Estimated price
- €70–180
Flights from Frankfurt to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- €90–300
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €60–150
Flights from Zurich Airport to Florence Peretola Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- €75–210
Flights from Frankfurt to Venice Marco Polo Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €85–270
- Website
- airdolomiti.it
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €110–320
Flights from Frankfurt to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- €95–300
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €60–150
Flights from Zurich Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 10m
- When
- Tuesday, Wednesday, Thursday, and Saturday
- Estimated price
- €110–350
- Website
- swiss.com
Flights from Frankfurt to Florence Peretola Airport via Zurich Airport
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- €120–280
Flights from Stuttgart Airport to Fiumicino International Airport via Zurich Airport
- Ave. Duration
- 3h 40m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €100–260
Flights from Zurich Airport to Florence Peretola Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- €75–210
- Website
- easyjet.com
Flights from Frankfurt to Fiumicino International Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- €35–130
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €35–130
- Website
- condor.com
Flights from Frankfurt to Fiumicino International Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- €50–210
Flights from Frankfurt to Venice Marco Polo Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €60–240
- Website
- eurowings.com
Flights from Stuttgart Airport to Fiumicino International Airport
- Ave. Duration
- 1h 40m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- €70–180
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 21m
- Frequency
- Hourly
- Estimated price
- €27–65
- Website
- https://int.bahn.de/en
Train from Heidelberg, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 39 min
- Frequency
- Hourly
- Estimated price
- €18–40
- Website
- https://int.bahn.de/en
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- €13–28
- Website
- https://int.bahn.de/en
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 50m
- Frequency
- Once daily
- Estimated price
- €40–140
- Website
- https://www.ns.nl/en
- 2nd Class
- €40–60
- 1st Class
- €80–140
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Once daily
- Estimated price
- €12–40
- Website
- https://www.ns.nl/en
- 2nd Class
- €12–19
- 1st Class
- €23–40
- Phone
- +43 5 1717
- Website
- oebb.at
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 59m
- Frequency
- 6 times a week
- Estimated price
- €92–93
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Basel SBB to Lugano
- Ave. Duration
- 2h 54m
- Frequency
- Every 3 hours
- Estimated price
- €55–110
- Website
- https://www.sbb.ch/en
Train from Basel SBB to Chiasso
- Ave. Duration
- 3h 26m
- Frequency
- 4 times a day
- Estimated price
- €55–110
- Website
- https://www.sbb.ch/en
Train from Basel SBB to Zürich HB
- Ave. Duration
- 1h 13m
- Frequency
- Every 20 minutes
- Estimated price
- €21–40
- Website
- https://www.sbb.ch/en
- Phone
- +49 (0) 7531 915109
- info@sbb-deutschland.de
- Website
- sbb-deutschland.de
Train from Basel SBB to Lugano
- Ave. Duration
- 3h 21m
- Frequency
- Once daily
- Estimated price
- €20–25
- Schedules at
- sbb-deutschland.de
Train from Basel SBB to Chiasso
- Ave. Duration
- 3h 48m
- Frequency
- Once daily
- Estimated price
- €21–28
- Schedules at
- sbb-deutschland.de
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- trenord.it
Train from Lugano to Milano Porta Garibaldi
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- €6–8
- Website
- https://www.trenord.it/en/
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano P.Garibaldi to Perugia
- Ave. Duration
- 3h 42m
- Frequency
- 6 times a week
- Estimated price
- €40–80
- Schedules at
- trenitalia.com
Train from Roma Termini to Foligno
- Ave. Duration
- 1h 42m
- Frequency
- Once daily
- Estimated price
- €24–35
- Schedules at
- trenitalia.com
Train from Venezia Mestre to Firenze S.M.N.
- Ave. Duration
- 2h 1m
- Frequency
- Hourly
- Estimated price
- €30–60
- Schedules at
- trenitalia.com
- Phone
- +43 51717
- Website
- nightjet.com
Night train from Stuttgart Hbf to Venezia Mestre
- Ave. Duration
- 11h 54m
- Frequency
- Once daily
- Estimated price
- €65–270
- Website
- https://www.nightjet.com/en/#/home
- Sleeper Carriage
- €260–270
- Couchette Carriage
- €150–180
- Seating Carriage
- €65–80
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Venezia Mestre to Foligno
- Ave. Duration
- 5h 52m
- Frequency
- Twice a week
- Estimated price
- €30–55
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Assisi
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- €10–24
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Foligno
- Ave. Duration
- 1h 54m
- Frequency
- 3 times a day
- Estimated price
- €9–21
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Chiasso to Firenze S.M.N.
- Ave. Duration
- 4h 28m
- Frequency
- Once a week
- Estimated price
- €75–130
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €90–130
- 2nd Class
- €75–110
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Firenze S.M.N. to Assisi
- Ave. Duration
- 2h 33m
- Frequency
- Every 4 hours
- Estimated price
- €16–22
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Foligno
- Ave. Duration
- 1h 56m
- Frequency
- Hourly
- Estimated price
- €12–25
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Bologna Centrale to Florence Santa Maria Novella
- Ave. Duration
- 36 min
- Frequency
- Hourly
- Estimated price
- €13–35
- Website
- https://www.italotreno.it/en
Train from Venezia Mestre to Firenze S.M.N.
- Ave. Duration
- 2h 11m
- Frequency
- Once a week
- Estimated price
- €26–60
- Website
- https://www.italotreno.it/en
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Heidelberg Post Waypoint to Karlsruhe central train station
- Ave. Duration
- 44 min
- Frequency
- Hourly
- Estimated price
- €7–10
- Website
- https://www.flixbus.co.uk
Bus from Karlsruhe central train station to Florence Villa Constanza Bus Station
- Ave. Duration
- 14h 15m
- Frequency
- Once daily
- Estimated price
- €65–95
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Assisi
- Ave. Duration
- 2h 35m
- Frequency
- 5 times a week
- Estimated price
- €9–14
- Website
- https://www.flixbus.co.uk
- Phone
- +39 098 3520 315
- info@fsbusitaliafast.it
- Website
- simetbus.it
Bus from Ludwigshafen to Rimini
- Ave. Duration
- 10h 51m
- Frequency
- Once a week
- Estimated price
- €75–90
- Schedules at
- simetbus.it
- Phone
- +39 089 233 899
- salerno@autolineecurcio.it
- Website
- autolineecurcio.it
Bus from Rimini - Via Annibale Fada to Assisi - S.M. Angeli - fermata Hotel Antonelli
- Ave. Duration
- 4h 10m
- Frequency
- Twice daily
- Estimated price
- €2
- Website
- https://www.autolineecurcio.it/
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide
Italian Lakes: Getting around by train
Read the travel guide
More Questions & Answers
Book your Heidelberg to Assisi bus tickets online with Omio and FlixBus.
There are 2200+ hotels available in Assisi.










































































