There are 4 ways to get from Havana to Cayo Santa María by bus, train, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  7 h 10 min

  1. Take the bus from La Habana to Santa Clara Via Holguin
  2. Take the bus from Santa Clara to Cayo Santa María Viazul

$22 - $37

Cheapest option

Train, bus  •  8 h 11 min

  1. Take the train from Havana - La Coubre to Santa Clara Cienfuegos/La Habana
  2. Take the bus from Santa Clara to Cayo Santa María Viazul

$14 - $27

2 alternative options

Drive  •  4 h 44 min

  1. Drive from Havana to Cayo Santa María 242.8 miles

Fly, bus  •  9 h 58 min

  1. Fly from Havana (HAV) to Santa Clara (SNU) HAV - SNU
  2. Take the bus from Santa Clara to Cayo Santa María

$239 - $2,132

Questions & Answers

The cheapest way to get from Havana to Cayo Santa María is to train and bus which costs $13 - $27 and takes 8 h 11 min.

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The quickest way to get from Havana to Cayo Santa María is to bus which costs $21 - $40 and takes 7 h 10 min.

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No, there is no direct bus from Havana to Cayo Santa María. However, there are services departing from La Habana and arriving at Cayo Santa María via Santa Clara. The journey, including transfers, takes approximately 7 h 10 min.

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The distance between Havana and Cayo Santa María is 347 km. The road distance is 388.6 km.

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The best way to get from Havana to Cayo Santa María without a car is to bus which takes 7 h 10 min and costs $21 - $40.

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It takes approximately 7 h 10 min to get from Havana to Cayo Santa María, including transfers.

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Havana to Cayo Santa María bus services, operated by Viazul, depart from La Habana station.

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There is no direct flight from Havana Airport to Santa Clara Airport. The quickest flight takes 4 h 15 min and has one stopover.

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Havana to Cayo Santa María bus services, operated by Viazul, arrive at Cayo Santa María station.

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Yes, the driving distance between Havana to Cayo Santa María is 389 km. It takes approximately 4 h 44 min to drive from Havana to Cayo Santa María.

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Southwest Airlines, Delta, JetBlue Airways and American Airlines offer flights from Havana Airport to Santa Clara Airport.

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There are six+ hotels available in Cayo Santa María. Prices start at $100 USD per night.

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Map of how to get from Havana to Cayo Santa María.
Launch map view
  • Distance: 216.7 miles
  • Duration: 7 h 10 min

What companies run services between Havana, Cuba and Cayo Santa María, Sancti Spíritus, Cuba?

You can take a bus from Havana to Cayo Santa María via Santa Clara in around 7 h 10 min.

Airlines
American Airlines
Website
aa.com
Flights from Havana to Santa Clara via Miami
Ave. Duration
6 h 18 min
When
Every day
Estimated price
$150 - $550
JetBlue Airways
Website
jetblue.com
Flights from Havana to Santa Clara via Fort Lauderdale
Ave. Duration
4 h 50 min
When
Every day
Estimated price
$140 - $650
Train operators
Ferrocarriles de Cuba
Website
en.wikipedia.org
Train from Havana - La Coubre to Santa Clara
Ave. Duration
4 h 46 min
Frequency
On demand
Estimated price
$6 - $10
Schedules at
seat61.com
Bus operators
Viazul
Phone
+ 53 (07) 8836092
Email
sales@viazul.com
Website
viazul.com
Bus from La Habana to Santa Clara
Ave. Duration
3 h 45 min
Frequency
Twice daily
Estimated price
$14 - $21
Schedules at
viazul.com
Book at
viazul.com
Bus from Santa Clara to Cayo Santa María
Ave. Duration
2 h 25 min
Frequency
Once daily
Estimated price
$7 - $17
Schedules at
viazul.com

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