There are 7 ways to get from Harrisburg, Pa to Appleton by plane, bus (Flixbus), train, bus, car, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Harrisburg International Airport to Appleton International Airport
best- Fly from Harrisburg International Airport (MDT) to Appleton International Airport (ATW)plane MDT - ATW
6h 29m$85–395Bus (Flixbus)
- Take the bus from Harrisburg Bus Station to Chicago Bus Stationbus FlixBus N2640
- Take the bus from Chicago Bus Station to Appleton Transit Centerbus FlixBus 2550
22h$112–218Train, bus
- Take the train from Harrisburg to Pittsburgh Amtrak Stationtrain
- Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Milwaukeetrain
- Take the bus from Milwaukee to Appleton Amtrak Stationbus
22h 8m$141–288Drive 845.1 mi
- Drive from Harrisburg, Pa to Appletoncar 845.1 mi
14h 17m$155–223Bus to Penn State University Park Airport, fly to Appleton International Airport
- Take the bus from Harrisburg Bus Station to State College Regional Airportbus
- Fly from Penn State University Park Airport (SCE) to Appleton International Airport (ATW)plane SCE - ATW
7h 46m$110–434Fly Harrisburg International Airport to Green Bay
- Fly from Harrisburg International Airport (MDT) to Green Bay (GRB)plane MDT - GRB
7h 21m$102–406Bus via Detroit
- Take the bus from Harrisburg Bus Station to Detroit Bus Stationbus Greyhound US0420
- Take the bus from Detroit Bus Station to Appleton Transit Centerbus FlixBus 2550
24h 20m$113–220
Harrisburg, Pa to Appleton by bus (Flixbus)
Questions & Answers
The cheapest way to get from Harrisburg, Pa to Appleton is to bus which costs $110 - $220 and takes 22h.
The fastest way to get from Harrisburg, Pa to Appleton is to fly which takes 6h 29m and costs $85 - $400.
No, there is no direct bus from Harrisburg, Pa station to Appleton. However, there are services departing from Harrisburg Bus Station and arriving at Appleton Transit Center via Chicago Bus Station. The journey, including transfers, takes approximately 22h.
The distance between Harrisburg, Pa and Appleton is 681 miles. The road distance is 850 miles.
The best way to get from Harrisburg, Pa to Appleton without a car is to bus which takes 22h and costs $110 - $220.
It takes approximately 6h 29m to get from Harrisburg, Pa to Appleton, including transfers.
Harrisburg, Pa to Appleton bus services, operated by Flixbus USA, depart from Harrisburg Bus Station.
The best way to get from Harrisburg, Pa to Appleton is to fly which takes 6h 29m and costs $85 - $400. Alternatively, you can bus, which costs $110 - $220 and takes 22h.
Harrisburg, Pa to Appleton bus services, operated by Flixbus USA, arrive at Chicago Bus Station.
Appleton is 1h behind Harrisburg, Pa. It is currently 11:41 PM in Harrisburg, Pa and 10:41 PM in Appleton.
What companies run services between Harrisburg, Pa, PA, USA and Appleton, WI, USA?
United Airlines, Delta, and two other airlines fly from Harrisburg International Airport (MDT) to Appleton International Airport (ATW) every 3 hours. Alternatively, you can take a bus from Harrisburg Bus Station to Appleton Transit Center via Chicago Bus Station in around 22h.
- Website
- united.com
Flights from Harrisburg International Airport to Appleton International Airport via Chicago O'Hare
- Ave. Duration
- 5h 42m
- When
- Every day
- Estimated price
- $70–380
Flights from Penn State University Park Airport to Appleton International Airport via Chicago O'Hare
- Ave. Duration
- 5h 41m
- When
- Every day
- Estimated price
- $65–370
Flights from Penn State University Park Airport to Appleton International Airport via Washington Dulles, Chicago O'Hare
- Ave. Duration
- 7h 10m
- When
- Every day
- Estimated price
- $75–400
Flights from Harrisburg International Airport to Green Bay via Chicago O'Hare
- Ave. Duration
- 4h 53m
- When
- Every day
- Estimated price
- $70–380
- Website
- aa.com
Flights from Harrisburg International Airport to Appleton International Airport via Charlotte
- Ave. Duration
- 6h 1m
- When
- Every day
- Estimated price
- $90–450
Flights from Harrisburg International Airport to Appleton International Airport via Chicago O'Hare
- Ave. Duration
- 6h 32m
- When
- Every day
- Estimated price
- $70–380
Flights from Harrisburg International Airport to Green Bay via Chicago O'Hare
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $70–380
Flights from Harrisburg International Airport to Green Bay via Philadelphia, Chicago O'Hare
- Ave. Duration
- 9h 15m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–410
- Website
- delta.com
Flights from Harrisburg International Airport to Appleton International Airport via Detroit
- Ave. Duration
- 5h 25m
- When
- Every day
- Estimated price
- $65–370
Flights from Harrisburg International Airport to Appleton International Airport via Atlanta
- Ave. Duration
- 10h 42m
- When
- Every day
- Estimated price
- $100–490
Flights from Harrisburg International Airport to Green Bay via Detroit
- Ave. Duration
- 5h 15m
- When
- Every day
- Estimated price
- $65–360
Flights from Harrisburg International Airport to Green Bay via Atlanta
- Ave. Duration
- 5h 29m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–490
- Website
- allegiantair.com
Flights from Harrisburg International Airport to Appleton International Airport via Nashville
- Ave. Duration
- 6h 25m
- When
- Monday and Friday
- Estimated price
- $95–450
Flights from Harrisburg International Airport to Appleton International Airport via Orlando Sanford
- Ave. Duration
- 8h 41m
- When
- Wednesday
- Estimated price
- $140–600
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Harrisburg to Pittsburgh Amtrak Station
- Ave. Duration
- 5h 29m
- Frequency
- Once daily
- Estimated price
- $45–55
- Website
- https://www.amtrak.com/home.html
Train from Pittsburgh Amtrak Station to Chicago Union Station
- Ave. Duration
- 9h 46m
- Frequency
- Once daily
- Estimated price
- $60–110
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Milwaukee
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $21–40
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Harrisburg Bus Station to Chicago Bus Station
- Ave. Duration
- 16h 30m
- Frequency
- Once daily
- Estimated price
- $80–180
- Schedules at
- flixbus.com
Bus from Chicago Bus Station to Appleton Transit Center
- Ave. Duration
- 4h 30m
- Frequency
- 5 times a week
- Estimated price
- $30–45
- Schedules at
- flixbus.com
Bus from Milwaukee to Appleton Amtrak Station
- Ave. Duration
- 2h 10m
- Frequency
- 5 times a week
- Estimated price
- $14–85
- Schedules at
- flixbus.com
- Adult
- $14–85
Bus from Harrisburg Bus Station to State College Regional Airport
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $25–45
- Schedules at
- flixbus.com
Bus from Detroit Bus Station to Appleton Transit Center
- Ave. Duration
- 10h 15m
- Frequency
- 4 times a week
- Estimated price
- $55–100
- Schedules at
- flixbus.com
- Adult
- $55–100
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Milwaukee to Appleton Amtrak Station
- Ave. Duration
- 2h 24m
- Frequency
- Twice daily
- Website
- https://www.amtrak.com/home.html
- Phone
- 920 496 3600
- Website
- golamers.com
Bus from Milwaukee to Appleton Amtrak Station
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $24–65
- Schedules at
- golamers.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Harrisburg Bus Station to Detroit Bus Station
- Ave. Duration
- 13h 5m
- Frequency
- Once daily
- Estimated price
- $55–120
- Website
- https://www.greyhound.com/
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More Questions & Answers
Yes, the driving distance between Harrisburg, Pa to Appleton is 850 miles. It takes approximately 14h 17m to drive from Harrisburg, Pa to Appleton.
Book your Harrisburg, Pa to Appleton bus tickets online with Omio and FlixBus.
There are 76+ hotels available in Appleton.









