There are 8 ways to get from Harrisburg to Chicago by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Harrisburg to Chicago O'Hare  •  4 h 17 min

  1. Fly from Harrisburg (MDT) to Chicago O'Hare (ORD) MDT - ORD

$184 - $438

Cheapest option

Bus  •  16 h 41 min

  1. Take the bus from Harrisburg, Pa to Pittsburgh, Pa 1683 / ...
  2. Take the bus from Pittsburgh, Pa to Chicago, Il 1607

$79 - $203

6 alternative options

Bus to State College, fly to Chicago O'Hare  •  5 h 45 min

  1. Take the bus from Harrisburg, Pa to State College, Pa
  2. Fly from State College (SCE) to Chicago O'Hare (ORD) SCE - ORD

$271 - $432

Train to Philadelphia, fly to Chicago Midway  •  6 h 1 min

  1. Take the train from Harrisburg Amtrak to Philadelphia 30th Street Station Amtrak
  2. Fly from Philadelphia (PHL) to Chicago Midway (MDW) PHL - MDW

$169 - $506

Bus, train  •  15 h

  1. Take the bus from Harrisburg, Pa to Rs Sideling Hill, Pa
  2. Take the bus from Rs Sideling Hill, Pa to Pittsburgh, Pa
  3. Take the train from Pittsburgh Amtrak to Chicago Union Station Amtrak

$110 - $291

Train  •  16 h 9 min

  1. Take the train from Harrisburg Amtrak to Pittsburgh Amtrak Pennsylvanian
  2. Take the train from Pittsburgh Amtrak to Chicago Union Station Amtrak Capitol Limited

$122 - $325

Bus Barons Bus  •  21 h 39 min

  1. Take the bus from Harrisburg, Pa to Pittsburgh, Pa
  2. Take the bus from Pittsburgh, Pa to Akron, Oh
  3. Take the bus from Akron, OH to Chicago, IL

$81 - $178

Drive  •  10 h 48 min

  1. Drive from Harrisburg to Chicago 662.5 miles

$65 - $95

Questions & Answers

The cheapest way to get from Harrisburg to Chicago is to drive which costs $65 - $95 and takes 10 h 48 min.

More details

The quickest way to get from Harrisburg to Chicago is to fly which takes 4 h 17 min and costs $180 - $440.

More details

The distance between Harrisburg and Chicago is 917 km. The road distance is 1060 km.

Get driving directions

It takes approximately 4 h 17 min to get from Harrisburg to Chicago, including transfers.

More details

No, there is no direct bus from Harrisburg to Chicago. However, there are services departing from N 6th St & Reily St and arriving at Chicago, Il via Harrisburg, Pa and Pittsburgh, Pa. The journey, including transfers, takes approximately 16 h 41 min.

More details

No, there is no direct train from Harrisburg to Chicago. However, there are services departing from Harrisburg Amtrak and arriving at Chicago Union Station Amtrak via Pittsburgh Amtrak. The journey, including transfers, takes approximately 16 h 9 min.

More details

What companies run services between Harrisburg, PA, USA and Chicago, IL, USA?

United Airlines, American Airlines and two other airlines fly from Harrisburg to Chicago hourly. Alternatively, you can take a train from Harrisburg to Chicago via Pittsburgh Amtrak in around 16 h 9 min.

Airlines
Southwest Airlines
Website
southwest.com
Flights from Philadelphia to Chicago Midway
Ave. Duration
2 h 13 min
When
Every day
Estimated price
$170 - $900
United Airlines
Website
united.com
Flights from Harrisburg to Chicago O'Hare
Ave. Duration
1 h 58 min
When
Every day
Estimated price
$310 - $850
Flights from Harrisburg to Chicago O'Hare via Washington Dulles
Ave. Duration
4 h 12 min
When
Every day
Estimated price
$310 - $850
Flights from State College to Chicago O'Hare
Ave. Duration
1 h 58 min
When
Every day
Estimated price
$450 - $850
Flights from State College to Chicago O'Hare via Washington Dulles
Ave. Duration
4 h 39 min
When
Every day
Estimated price
$450 - $850
American Airlines
Website
aa.com
Flights from Harrisburg to Chicago O'Hare
Ave. Duration
2 h 12 min
When
Every day
Estimated price
$310 - $850
Flights from Harrisburg to Chicago O'Hare via Philadelphia
Ave. Duration
4 h 20 min
When
Every day
Estimated price
$310 - $850
Flights from State College to Chicago O'Hare via Philadelphia
Ave. Duration
4 h 35 min
When
Every day
Estimated price
$390 - $900
Delta
Website
delta.com
Flights from Harrisburg to Chicago O'Hare via Detroit
Ave. Duration
3 h 56 min
When
Every day
Estimated price
$350 - $900
Flights from State College to Chicago O'Hare via Detroit
Ave. Duration
3 h 59 min
When
Every day
Estimated price
$360 - $800
Flights from Philadelphia to Chicago Midway via Detroit
Ave. Duration
3 h 41 min
When
Monday to Friday
Estimated price
$130 - $750
Train operators
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Harrisburg Amtrak to Philadelphia 30th Street Station Amtrak
Ave. Duration
1 h 45 min
Frequency
Hourly
Estimated price
$30 - $65
Website
amtrak.com
Coach Seat
$30 - $45
Flexi Coach Seat
$50 - $80
Business Coach Seat
$45 - $65
Room
$160 - $220
Train from Pittsburgh Amtrak to Chicago Union Station Amtrak
Ave. Duration
9 h 46 min
Frequency
Once daily
Estimated price
$75 - $210
Website
amtrak.com
Coach Seat
$75 - $110
Flexi Coach Seat
$130 - $190
Business Coach Seat
$140 - $210
Room
$320 - $440
Train from Harrisburg Amtrak to Pittsburgh Amtrak
Ave. Duration
5 h 23 min
Frequency
Once daily
Estimated price
$45 - $120
Website
amtrak.com
Coach Seat
$45 - $70
Flexi Coach Seat
$80 - $120
Business Coach Seat
$80 - $120
Room
$220 - $300
Bus operators
Greyhound USA
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Harrisburg, Pa to State College, Pa
Ave. Duration
1 h 50 min
Frequency
Hourly
Estimated price
$15 - $35
Website
greyhound.com
Economy
$15 - $22
Flexible
$26 - $35
Bus from Harrisburg, Pa to Rs Sideling Hill, Pa
Ave. Duration
2 h 4 min
Frequency
Hourly
Estimated price
$16 - $40
Website
greyhound.com
Economy
$16 - $24
Flexible
$28 - $40
Bus from Rs Sideling Hill, Pa to Pittsburgh, Pa
Ave. Duration
1 h 40 min
Frequency
Hourly
Estimated price
$19 - $45
Website
greyhound.com
Economy
$19 - $29
Flexible
$30 - $45
Bus from Harrisburg, Pa to Pittsburgh, Pa
Ave. Duration
4 h 15 min
Frequency
Hourly
Estimated price
$27 - $70
Website
greyhound.com
Economy
$27 - $45
Flexible
$50 - $70
Bus from Pittsburgh, Pa to Chicago, Il
Ave. Duration
11 h
Frequency
Every 2 hours
Estimated price
$50 - $130
Website
greyhound.com
Economy
$50 - $80
Flexible
$95 - $130
Bus from Pittsburgh, Pa to Akron, Oh
Ave. Duration
2 h 30 min
Frequency
Hourly
Estimated price
$17 - $40
Website
greyhound.com
Economy
$17 - $26
Flexible
$30 - $40
Fullington Trailways
Phone
+1 800.942.8287
Website
fullingtontours.com
Bus from Harrisburg to State College, PA
Ave. Duration
1 h 45 min
Frequency
Twice daily
Estimated price
$23 - $40
Schedules at
fullingtontours.com
Book at
fab.tdstickets.com
bus
Bus from Harrisburg Transportation Center to State College
Ave. Duration
1 h 35 min
Frequency
Twice a week

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