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How to get fromHarlem to Buffaloby bus, plane, train (Amtrak), car, subway, train, or bus (Flixbus)

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There are 10 ways to get from Harlem to Buffalo by bus, plane, train (Amtrak), car, subway, train, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Laguardia Airport, fly to Buffalo Niagara International Airport

    best
    1. Take the bus from W 125 St/Malcolm X Blvd to Laguardia Rd/94 Stbus bus
    2. Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane plane LGA - BUF
    4h 12m
    $98–685

  2. Bus via 42 St-Port Authority Bus Terminal

    cheapest
    1. Take the bus from New York to Buffalobus bus Adt N816-D / ...
    9h 18m
    $63–283

  3. Train via Yonkers

    1. Take the train from Yonkers Amtrak Station to Buffalotrain train Empire Service / ...
    9h 21m
    $117–291

  4. Drive  361.8 mi

    1. Drive from Harlem to Buffalocar car 361.8 mi
    7h 15m
    $66–96

  5. Line 2 subway, train to John F. Kennedy International Airport, fly to Buffalo Niagara International Airport

    1. Take the subway from 125 St to 34 St-Penn Stationsubway subway
    2. Take the train from New York Penn Station to Jamaicatrain train
    3. Fly from John F. Kennedy International Airport (JFK) to Buffalo Niagara International Airport (BUF)plane plane JFK - BUF
    4h 38m
    $87–480

  6. Line 2 subway, train to Newark Liberty International Airport, fly to Buffalo Niagara International Airport

    1. Take the subway from 125 St to 34 St-Penn Stationsubway subway
    2. Take the train from New York Penn Station to Newark Airport Railroad Stationtrain train
    3. Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane plane EWR - BUF
    4h 36m
    $99–549

  7. Fly Laguardia Airport to Rochester, bus

    1. Fly from Laguardia Airport (LGA) to Rochester (ROC)plane plane LGA - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    5h 33m
    $152–848

  8. Fly John F. Kennedy International Airport to Rochester, bus

    1. Fly from John F. Kennedy International Airport (JFK) to Rochester (ROC)plane plane JFK - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    6h
    $131–663

  9. Train

    1. Take the train from New York Penn Station to Buffalotrain train VIA Rail
    9h 40m
    $113–283

  10. Bus (Flixbus)

    1. Take the bus from New York Midtown to Buffalobus bus FlixBus 2686 / ...
    10h 34m
    $68–117

Harlem to Buffalo by subway and bus

Calendar33Weekly Services
Duration9h 18mAverage Duration
Ticket$63Cheapest Price
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Comparing Your Travel Options

Map of how to get from Harlem to Buffalo.ExpandLaunch map view
  • Distance: 308.6 mi
  • Duration: 4h 12m

What companies run services between Harlem, NY, USA and Buffalo, NY, USA?

Trailways operates a bus from New York to Buffalo 5 times a day. Tickets cost $60–280 and the journey takes 8h. Alternatively, Amtrak operates a train from Yonkers Amtrak Station to Buffalo twice daily. Tickets cost $230–360 and the journey takes 7h 58m. VIA Rail also services this route once daily.

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