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How to get fromHarlem to Buffaloby bus, plane, train (Amtrak), bus (Greyhound), car, subway, train or bus (Flixbus)

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There are 9 ways to get from Harlem to Buffalo by bus, plane, train (Amtrak), bus (Greyhound), car, subway, train, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Laguardia Airport, fly to Buffalo Niagara International Airport

    best
    1. Take the bus from E 125 St/Lexington Av to Laguardia Rd/94 Stbus bus
    2. Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane plane LGA - BUF
    3h 54m
    $125–859

  2. Bus

    cheapest
    1. Take the bus from Port Authority Bus Terminal to Buffalobus bus Greyhound US0215 / ...
    9h 58m
    $58–253

  3. Train via Yonkers

    1. Take the train from Yonkers Amtrak Station to Buffalotrain train Empire Service / ...
    9h 31m
    $68–132

  4. Drive 361.8 mi

    1. Drive from Harlem to Buffalocar car 361.8 mi
    7h 16m
    $66–96

  5. Line 2 subway, train to John F. Kennedy International Airport, fly to Buffalo Niagara International Airport

    1. Take the subway from 125 St to 34 St-Penn Stationsubway subway
    2. Take the train from New York Penn Station to Jamaicatrain train
    3. Fly from John F. Kennedy International Airport (JFK) to Buffalo Niagara International Airport (BUF)plane plane JFK - BUF
    4h 11m
    $118–724

  6. Line 2 subway, train to Newark Liberty International Airport, fly to Buffalo Niagara International Airport

    1. Take the subway from 125 St to 34 St-Penn Stationsubway subway
    2. Take the train from New York Penn Station to Newark Airport Railroad Stationtrain train
    3. Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane plane EWR - BUF
    4h 19m
    $125–783

  7. Fly Laguardia Airport to Rochester, bus

    1. Fly from Laguardia Airport (LGA) to Rochester (ROC)plane plane LGA - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    5h 18m
    $290–703

  8. Train

    1. Take the train from New York Penn Station to Buffalotrain train VIA Rail
    9h 40m
    $63–123

  9. Bus via 7 Av/W 31 St (Flixbus)

    1. Take the bus from New York Midtown to Buffalobus bus FlixBus 2686 / ...
    10h 24m
    $58–117

Harlem to Buffalo by train

Calendar21Weekly Trains
Duration9h 31mAverage Duration
Ticket$68Cheapest Price
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Questions & Answers

What companies run services between Harlem, NY, USA and Buffalo, NY, USA?

Amtrak operates a train from Yonkers Amtrak Station to Buffalo twice daily. Tickets cost $120–260 and the journey takes 8h 8m. VIA Rail also services this route once daily. Alternatively, Greyhound USA operates a bus from Port Authority Bus Terminal to Buffalo 4 times a day. Tickets cost $70–140 and the journey takes 8h 40m. Trailways also services this route once daily.

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