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There are 10 ways to get from Harlem-125th St. to Buffalo by plane, subway, train, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly New York La Guardia to Buffalo  •  4h 4m

  1. Fly from New York La Guardia (LGA) to Buffalo (BUF) LGA - BUF

$75 - $375

Cheapest option

Bus Megabus  •  10h 45m

  1. Take the bus from New York, NY to Buffalo, NY

$38 - $63

8 alternative options

Line 6 subway to Newark, fly to Buffalo  •  4h 9m

  1. Take the line 6 subway from 125 St to Grand Central - 42 St
  2. Fly from Newark (EWR) to Buffalo (BUF) EWR - BUF

$112 - $482

Line 2 subway, train to New York JFK, fly to Buffalo  •  4h 20m

  1. Take the line 2 subway from 125 St to 34 St - Penn Station
  2. Take the train from Penn Station to Jamaica
  3. Fly from New York JFK (JFK) to Buffalo (BUF) JFK - BUF

$79 - $376

Train to Philadelphia, fly to Buffalo  •  5h 38m

  1. Take the train from New York Penn Station to Philadelphia 30th Street Station
  2. Fly from Philadelphia (PHL) to Buffalo (BUF) PHL - BUF

$237 - $922

Fly New York La Guardia to Rochester, train  •  6h 22m

  1. Fly from New York La Guardia (LGA) to Rochester (ROC) LGA - ROC
  2. Take the train from Rochester Amtrak Station to Buffalo Amtrak Station

$125 - $469

Fly Newark to Rochester, train  •  6h 31m

  1. Fly from Newark (EWR) to Rochester (ROC) EWR - ROC
  2. Take the train from Rochester Amtrak Station to Buffalo Amtrak Station

$137 - $516

Bus Trailways New York  •  8h 45m

  1. Take the bus from New York, NY - Port Authority Bus Terminal to Buffalo, NY Ny / ...

$43 - $113

Train  •  8h 54m

  1. Take the train from Yonkers Amtrak Station to Buffalo Amtrak Station Maple Leaf / ...

$70 - $194

Drive  •  6h 50m

  1. Drive from Harlem-125th St. to Buffalo 381.9 miles

$35 - $55

Questions & Answers

The cheapest way to get from Harlem-125th St. to Buffalo is to drive which costs $35 - $55 and takes 6h 50m.

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The quickest way to get from Harlem-125th St. to Buffalo is to fly which costs $75 - $380 and takes 4h 4m.

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No, there is no direct train from Harlem-125th St. to Buffalo station. However, there are services departing from Harlem-125th St. and arriving at Buffalo Amtrak Station via Yonkers Amtrak Station. The journey, including transfers, takes approximately 8h 54m.

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The distance between Harlem-125th St. and Buffalo is 294 miles. The road distance is 381.9 miles.

Get driving directions

The best way to get from Harlem-125th St. to Buffalo without a car is to bus which takes 8h 45m and costs $40 - $120.

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It takes approximately 4h 4m to get from Harlem-125th St. to Buffalo, including transfers.

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Harlem-125th St. to Buffalo train services, operated by Amtrak, arrive at Yonkers Amtrak Station.

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The best way to get from Harlem-125th St. to Buffalo is to fly which takes 4h 4m and costs $75 - $380. Alternatively, you can bus, which costs $40 - $120 and takes 8h 45m, you could also train, which costs $70 - $200 and takes 8h 54m.

Mode details

The quickest flight from New York La Guardia Airport to Buffalo Airport is the direct flight which takes 1h 31m.

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Harlem-125th St. to Buffalo train services, operated by Amtrak, arrive at Buffalo Amtrak Station.

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Map of how to get from Harlem-125th St. to Buffalo.
Launch map view
  • Distance: 293.7 miles
  • Duration: 4h 4m

What companies run services between Harlem-125th St., NY, USA and Buffalo, NY, USA?

Delta, United Airlines and American Airlines fly from Harlem-125th St. to Buffalo every 4 hours. Alternatively, Trailways New York operates a bus from Harlem-125th St. to Buffalo 4 times a day. Tickets cost $55 - $95 and the journey takes 7h 40m. Two other operators also service this route.

Airlines
United Airlines
Website
united.com
Flights from New York La Guardia to Buffalo via Washington Dulles
Ave. Duration
3h 41m
When
Every day
Estimated price
$220 - $1,600
Flights from Newark to Buffalo
Ave. Duration
1h 27m
When
Every day
Estimated price
$120 - $850
Flights from Newark to Buffalo via Washington Dulles
Ave. Duration
3h 39m
When
Every day
Estimated price
$120 - $850
Flights from Newark to Rochester
Ave. Duration
1h 24m
When
Every day
Estimated price
$120 - $600
Delta
Website
delta.com
Flights from New York La Guardia to Buffalo
Ave. Duration
1h 34m
When
Every day
Estimated price
$100 - $700
Flights from New York La Guardia to Buffalo via Boston
Ave. Duration
3h 57m
When
Monday to Friday
Estimated price
$100 - $700
Flights from New York JFK to Buffalo
Ave. Duration
1h 37m
When
Every day
Estimated price
$90 - $650
Flights from New York La Guardia to Rochester
Ave. Duration
1h 30m
When
Every day
Estimated price
$90 - $600
American Airlines
Website
aa.com
Flights from New York La Guardia to Buffalo via Philadelphia
Ave. Duration
3h 37m
When
Every day
Estimated price
$130 - $800
Flights from New York La Guardia to Buffalo via Reagan Washington
Ave. Duration
4h
When
Sunday
Estimated price
$130 - $800
Flights from Philadelphia to Buffalo
Ave. Duration
1h 24m
When
Every day
Estimated price
$200 - $1,100
JetBlue Airways
Website
jetblue.com
Flights from New York JFK to Buffalo
Ave. Duration
1h 30m
When
Every day
Estimated price
$100 - $650
Flights from New York JFK to Buffalo via Boston
Ave. Duration
3h 38m
When
Monday to Friday
Estimated price
$100 - $650
Train operators
Long Island Rail Road
Phone
+1 718-217-5477
Website
mta.info
Train from Penn Station to Jamaica
Ave. Duration
21m
Frequency
Every 15 minutes
Estimated price
$4 - $6
Website
LIRR
Amtrak Acela Express

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak Acela Express
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from New York Penn Station to Philadelphia 30th Street Station
Ave. Duration
1h 8m
Frequency
Every 30 minutes
Estimated price
$75 - $210
Website
amtrak.com
Business Seat
$75 - $180
First Class Seat
$150 - $210
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Rochester Amtrak Station to Buffalo Amtrak Station
Ave. Duration
1h 17m
Frequency
3 times a day
Estimated price
$26 - $55
Website
amtrak.com
Coach Seat
$26 - $40
Flexi Coach Seat
$45 - $70
Business Coach Seat
$35 - $55
Room
$140 - $210
Train from Yonkers Amtrak Station to Buffalo Amtrak Station
Ave. Duration
7h 30m
Frequency
Twice daily
Estimated price
$65 - $180
Website
amtrak.com
Coach Seat
$65 - $100
Flexi Coach Seat
$120 - $170
Business Coach Seat
$130 - $180
Room
$290 - $410
VIA Rail
Phone
+1 1 888 842-7245
Website
viarail.ca
Train from Rochester to Buffalo
Ave. Duration
1h 22m
Frequency
Once daily
Estimated price
$40 - $85
Website
viarail.ca
Escape
$19 - $40
Economy
$40 - $55
EconomyPlus
$55 - $85
Business
$55 - $80
Train from Yonkers to Buffalo
Ave. Duration
7h 40m
Frequency
Once daily
Estimated price
$90 - $170
Website
viarail.ca
Escape
$65 - $90
Economy
$90 - $130
EconomyPlus
$110 - $170
Business
$150 - $220
Bus operators
Trailways New York
Phone
(800) 858-8555
Website
trailwaysny.com
Bus from New York, NY - Port Authority Bus Terminal to Buffalo, NY
Ave. Duration
7h 40m
Frequency
4 times a day
Estimated price
$55 - $95
Book at
trailwaysny.com
Greyhound Canada
Phone
+1 1-800-661-8747
Email
Canada.info@greyhound.ca
Website
greyhound.ca
Bus from New York, NY - 625 8th Ave P.A. Terminal to Buffalo, NY - 181 Ellicott Street
Ave. Duration
9h 30m
Frequency
Every 4 hours
Estimated price
$35 - $95
Website
Greyhound.ca
Advanced Purchase
$35 - $55
Online Fare
$45 - $75
Standard Fare
$60 - $95
Refundable
$70 - $100
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from New York, Ny to Buffalo, Ny
Ave. Duration
9h 55m
Frequency
Every 4 hours
Estimated price
$40 - $110
Website
greyhound.com
Economy
$40 - $70
Flexible
$80 - $110

Want to know more about travelling around United States

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More Questions & Answers

Yes, the driving distance between Harlem-125th St. to Buffalo is 382 miles. It takes approximately 6h 50m to drive from Harlem-125th St. to Buffalo.

Get driving directions

American Airlines, Delta and United Airlines offer flights from New York La Guardia Airport to Buffalo Airport.

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There are 140+ hotels available in Buffalo. Prices start at $59 USD per night.

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