There are 7 ways to get from Harlem-125th St. to Buffalo by subway, plane, train, bus, night bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Line 4 subway, subway to New York La Guardia, fly  •  3 h 45 min

  1. Take the line 4 subway from 125 St to 59 St
  2. Take the subway from Lexington Av/59 St to Jackson Hts - Roosevelt Av
  3. Fly from New York La Guardia (LGA) to Buffalo (BUF) LGA - BUF

$75 - $390

Cheapest option

Night bus  •  8 h 15 min

  1. Take the night bus from New York, Ny to Buffalo, Ny 318

$43 - $113

5 alternative options

Line 4 subway to Newark, fly  •  3 h 54 min

  1. Take the line 4 subway from 125 St to Grand Central - 42 St
  2. Fly from Newark (EWR) to Buffalo (BUF) EWR - BUF

$112 - $497

Line 2 subway, train to New York JFK, fly  •  4 h 4 min

  1. Take the line 2 subway from 125 St to 34 St - Penn Station
  2. Take the train from Penn Station to Jamaica
  3. Fly from New York JFK (JFK) to Buffalo (BUF) JFK - BUF

$77 - $389

Bus  •  8 h 12 min

  1. Take the bus from New York, NY - Port Authority to Buffalo, NY Nyc

$53 - $103

Train  •  9 h 4 min

  1. Take the train from Yonkers to Buffalo VIA Rail / ...

$65 - $214

Drive  •  6 h 50 min

  1. Drive from Harlem-125th St. to Buffalo 381.9 miles

$35 - $55

Questions & Answers

The cheapest way to get from Harlem-125th St. to Buffalo is to drive which costs $35 - $55 and takes 6 h 50 min.

More details

The quickest way to get from Harlem-125th St. to Buffalo is to line 4 subway and subway and fly which costs $75 - $390 and takes 3 h 45 min.

More details

No, there is no direct train from Harlem-125th St. to Buffalo. However, there are services departing from Harlem-125th St. and arriving at Buffalo via Yonkers. The journey, including transfers, takes approximately 9 h 4 min.

More details

The distance between Harlem-125th St. and Buffalo is 294 miles. The road distance is 381.9 miles.

Get driving directions

The best way to get from Harlem-125th St. to Buffalo without a car is to bus which takes 8 h 12 min and costs $50 - $110.

More details

It takes approximately 3 h 45 min to get from Harlem-125th St. to Buffalo, including transfers.

More details

Harlem-125th St. to Buffalo train services, operated by VIA Rail, depart from Yonkers station.

More details

The best way to get from Harlem-125th St. to Buffalo is to bus which takes 8 h 12 min and costs $50 - $110. Alternatively, you can train, which costs $65 - $220 and takes 9 h 4 min.

Mode details

The quickest flight from New York La Guardia Airport to Buffalo Airport is the direct flight which takes 1 h 21 min.

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Harlem-125th St. to Buffalo train services, operated by VIA Rail, arrive at Buffalo station.

More details

Yes, the driving distance between Harlem-125th St. to Buffalo is 382 miles. It takes approximately 6 h 50 min to drive from Harlem-125th St. to Buffalo.

Get driving directions

United Airlines, American Airlines and Delta offer flights from New York La Guardia Airport to Buffalo Airport.

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Map of how to get from Harlem-125th St. to Buffalo.
Launch map view
  • Distance: 293.7 miles
  • Duration: 3 h 45 min

What companies run services between Harlem-125th St., NY, USA and Buffalo, NY, USA?

Trailways New York operates a bus from Harlem-125th St. to Buffalo hourly. Tickets cost $50 - $100 and the journey takes 7 h. Alternatively, VIA Rail operates a train from Harlem-125th St. to Buffalo every 3 hours. Tickets cost $60 - $200 and the journey takes 7 h 40 min. Amtrak also services this route twice daily.

Airlines
Delta
Website
delta.com
Flights from New York La Guardia to Buffalo
Ave. Duration
1 h 30 min
When
Every day
Estimated price
$100 - $700
Flights from New York JFK to Buffalo
Ave. Duration
1 h 38 min
When
Every day
Estimated price
$90 - $650
United Airlines
Website
united.com
Flights from New York La Guardia to Buffalo via Washington Dulles
Ave. Duration
3 h 39 min
When
Every day
Estimated price
$220 - $1,600
Flights from Newark to Buffalo
Ave. Duration
1 h 23 min
When
Every day
Estimated price
$120 - $850
Flights from Newark to Buffalo via Washington Dulles
Ave. Duration
3 h 24 min
When
Every day
Estimated price
$120 - $850
JetBlue Airways
Website
jetblue.com
Flights from New York JFK to Buffalo
Ave. Duration
1 h 23 min
When
Every day
Estimated price
$100 - $650
American Airlines
Website
aa.com
Flights from New York La Guardia to Buffalo via Reagan Washington
Ave. Duration
3 h 36 min
When
Monday to Friday
Estimated price
$130 - $800
Flights from New York La Guardia to Buffalo via Philadelphia
Ave. Duration
3 h 38 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$130 - $800
Train operators
New York City Transit (MTA)
Website
mta.info
Subway from 125 St to 59 St
Ave. Duration
9 min
Frequency
Every 5 minutes
Estimated price
$3
Website
mta.info
Subway from Lexington Av/59 St to Jackson Hts - Roosevelt Av
Ave. Duration
15 min
Frequency
Every 10 minutes
Estimated price
$3
Website
mta.info
Subway from 125 St to Grand Central - 42 St
Ave. Duration
12 min
Frequency
Every 5 minutes
Estimated price
$3
Website
mta.info
Subway from 125 St to 34 St - Penn Station
Ave. Duration
16 min
Frequency
Every 5 minutes
Estimated price
$3
Website
mta.info
Long Island Rail Road
Website
mta.info
Train from Penn Station to Jamaica
Ave. Duration
21 min
Frequency
Every 15 minutes
Estimated price
$4 - $6
Schedules at
mta.info
VIA Rail
Phone
+1 1 888 842-7245
Website
viarail.ca
Train from Yonkers to Buffalo
Ave. Duration
7 h 40 min
Frequency
Every 3 hours
Estimated price
$60 - $200
Website
viarail.ca
Escape
$60 - $85
Economy
$100 - $140
Economy Plus
$140 - $200
Business
$150 - $210
Business Plus/Sleeper
$260 - $370
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Yonkers Amtrak to Buffalo Exchange Street Amtrak
Ave. Duration
7 h 30 min
Frequency
Twice daily
Estimated price
$65 - $180
Website
amtrak.com
Coach Seat
$65 - $100
Flexi Coach Seat
$120 - $170
Business Coach Seat
$130 - $180
Room
$290 - $410
Bus operators
Trailways New York
Phone
(800) 858-8555
Website
trailwaysny.com
Bus from New York, NY - Port Authority to Buffalo, NY
Ave. Duration
7 h
Frequency
Hourly
Estimated price
$50 - $100
Book at
trailwaysny.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Night bus from New York, Ny to Buffalo, Ny
Ave. Duration
7 h 10 min
Frequency
Hourly
Estimated price
$40 - $110
Website
greyhound.com
Economy
$40 - $70
Flexible
$80 - $110

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