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  • Greyhound USA
  • VIA Rail
  • Amtrak
  • Acela Express
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There are 12 ways to get from Harlem-125th St. to Syracuse by bus, train, car, subway or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus OurBus  •  5 h 55 min

  1. Take the bus from New York, NY to Syracuse, NY New York-Syracuse Route

$19 - $38

11 alternative options

Bus Greyhound USA  •  6 h 17 min

  1. Take the bus from New York, Ny to Syracuse, Ny 4262 / ...

$32 - $73

Train  •  6 h 24 min

  1. Take the train from Yonkers Amtrak to Syracuse Regional Transportation Center Maple Leaf / ...

$55 - $144

Train via Croton-Harmon  •  7 h 4 min

  1. Take the train from Harlem-125th St. to Croton-Harmon Hudson
  2. Take the train from Croton-Harmon Amtrak to Syracuse Regional Transportation Center Empire Service / ...

$56 - $142

Drive  •  4 h 24 min

  1. Drive from Harlem-125th St. to Syracuse 254.8 miles

$24 - $40

Line 6 subway, subway to New York La Guardia, fly to Syracuse  •  4 h 9 min

  1. Take the line 6 subway from 125 St to 68 St - Hunter College
  2. Take the subway from Lexington Av/63 St to Jackson Hts - Roosevelt Av
  3. Fly from New York La Guardia (LGA) to Syracuse (SYR) LGA - SYR

$88 - $388

Line 6 subway to Newark, fly to Syracuse  •  4 h 22 min

  1. Take the line 6 subway from 125 St to Grand Central - 42 St
  2. Fly from Newark (EWR) to Syracuse (SYR) EWR - SYR

$110 - $485

Line 2 subway, train to New York JFK, fly to Syracuse  •  4 h 27 min

  1. Take the line 2 subway from 125 St to 34 St - Penn Station
  2. Take the train from Penn Station to Jamaica
  3. Fly from New York JFK (JFK) to Syracuse (SYR) JFK - SYR

$92 - $319

Train to Philadelphia, fly to Syracuse  •  5 h 50 min

  1. Take the train from New York Penn Station to Philadelphia 30th Street Station
  2. Fly from Philadelphia (PHL) to Syracuse (SYR) PHL - SYR

$275 - $935

Fly New York La Guardia to Rochester, train  •  6 h 20 min

  1. Fly from New York La Guardia (LGA) to Rochester (ROC) LGA - ROC
  2. Take the train from Rochester Amtrak to Syracuse Regional Transportation Center

$126 - $474

Fly Newark to Elmira/Corning, bus  •  6 h 38 min

  1. Fly from Newark (EWR) to Elmira/Corning (ELM) EWR - ELM
  2. Take the bus from Elmira, NY to Destiny USA

$221 - $890

Line 6 subway to Newark, fly to Rochester, train  •  6 h 29 min

  1. Take the line 6 subway from 125 St to Grand Central - 42 St
  2. Fly from Newark (EWR) to Rochester (ROC) EWR - ROC
  3. Take the train from Rochester Amtrak to Syracuse Regional Transportation Center

$138 - $521

Questions & Answers

The cheapest way to get from Harlem-125th St. to Syracuse is to drive which costs $24 - $40 and takes 4 h 24 min.

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The quickest way to get from Harlem-125th St. to Syracuse is to line 6 subway and subway and fly which costs $85 - $390 and takes 4 h 9 min.

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No, there is no direct train from Harlem-125th St. to Syracuse. However, there are services departing from Harlem-125th St. and arriving at Syracuse Regional Transportation Center via Yonkers Amtrak. The journey, including transfers, takes approximately 6 h 24 min.

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The distance between Harlem-125th St. and Syracuse is 193 miles. The road distance is 254.8 miles.

Get driving directions

The best way to get from Harlem-125th St. to Syracuse without a car is to bus which takes 5 h 55 min and costs $18 - $40.

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It takes approximately 5 h 55 min to get from Harlem-125th St. to Syracuse, including transfers.

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Harlem-125th St. to Syracuse train services, operated by Amtrak, depart from Yonkers Amtrak station.

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The best way to get from Harlem-125th St. to Syracuse is to bus which takes 5 h 55 min and costs $18 - $40. Alternatively, you can train, which costs $55 - $150 and takes 6 h 24 min.

Mode details

The quickest flight from New York La Guardia Airport to Syracuse Airport is the direct flight which takes 1 h 9 min.

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Harlem-125th St. to Syracuse train services, operated by Amtrak, arrive at Syracuse Regional Transportation Center station.

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Map of how to get from Harlem-125th St. to Syracuse.
Launch map view
  • Distance: 193.2 miles
  • Duration: 5 h 55 min

What companies run services between Harlem-125th St., NY, USA and Syracuse, NY, USA?

OurBus operates a bus from Harlem-125th St. to Syracuse 5 times a week. Tickets cost $16 - $35 and the journey takes 4 h 35 min. Alternatively, Amtrak operates a train from Harlem-125th St. to Syracuse twice daily. Tickets cost $50 - $130 and the journey takes 4 h 59 min. VIA Rail also services this route once daily.

Airlines
United Airlines
Website
united.com
Flights from Newark to Syracuse
Ave. Duration
1 h 16 min
When
Every day
Estimated price
$100 - $800
Flights from Philadelphia to Syracuse via Washington Dulles
Ave. Duration
3 h 13 min
When
Wednesday and Sunday
Estimated price
$290 - $2,100
Flights from New York La Guardia to Rochester via Washington Dulles
Ave. Duration
3 h 35 min
When
Every day
Estimated price
$200 - $1,200
Flights from Newark to Elmira/Corning
Ave. Duration
1 h 11 min
When
Every day
Estimated price
$150 - $800
Flights from Newark to Rochester
Ave. Duration
1 h 22 min
When
Every day
Estimated price
$120 - $600
Delta
Website
delta.com
Flights from New York La Guardia to Syracuse
Ave. Duration
1 h 16 min
When
Every day
Estimated price
$70 - $750
Flights from New York JFK to Syracuse
Ave. Duration
1 h 24 min
When
Every day
Estimated price
$70 - $500
Flights from New York La Guardia to Rochester
Ave. Duration
1 h 29 min
When
Every day
Estimated price
$90 - $600
American Airlines
Website
aa.com
Flights from Philadelphia to Syracuse
Ave. Duration
1 h 15 min
When
Every day
Estimated price
$250 - $1,400
JetBlue Airways
Website
jetblue.com
Flights from New York JFK to Syracuse
Ave. Duration
1 h 11 min
When
Every day
Estimated price
$95 - $550
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Yonkers Amtrak to Syracuse Regional Transportation Center
Ave. Duration
4 h 59 min
Frequency
Twice daily
Estimated price
$50 - $130
Website
amtrak.com
Coach Seat
$50 - $75
Flexi Coach Seat
$85 - $130
Business Coach Seat
$90 - $130
Room
$230 - $320
Train from Croton-Harmon Amtrak to Syracuse Regional Transportation Center
Ave. Duration
4 h 39 min
Frequency
4 times a day
Estimated price
$45 - $120
Website
amtrak.com
Coach Seat
$45 - $70
Flexi Coach Seat
$85 - $130
Business Coach Seat
$85 - $120
Room
$220 - $310
Train from Rochester Amtrak to Syracuse Regional Transportation Center
Ave. Duration
1 h 15 min
Frequency
5 times a day
Estimated price
$27 - $60
Website
amtrak.com
Coach Seat
$27 - $40
Flexi Coach Seat
$45 - $70
Business Coach Seat
$40 - $60
Room
$150 - $210
VIA Rail
Phone
+1 1 888 842-7245
Website
viarail.ca
Train from Yonkers to Syracuse
Ave. Duration
4 h 59 min
Frequency
Once daily
Estimated price
$70 - $130
Website
viarail.ca
Escape
$45 - $70
Economy
$70 - $100
EconomyPlus
$90 - $130
Business
$110 - $160
Train from Croton-Harmon to Syracuse
Ave. Duration
4 h 40 min
Frequency
Once daily
Estimated price
$65 - $130
Website
viarail.ca
Escape
$45 - $65
Economy
$65 - $95
EconomyPlus
$90 - $130
Business
$110 - $150
Train from Rochester to Syracuse
Ave. Duration
1 h 15 min
Frequency
Once daily
Estimated price
$40 - $85
Website
viarail.ca
Escape
$20 - $45
Economy
$40 - $60
EconomyPlus
$60 - $85
Business
$55 - $85
Metro-North Railroad (MNR)
Phone
+1 877-690-5116
Website
mta.info
Train from Harlem-125th St. to Croton-Harmon
Ave. Duration
1 h 1 min
Frequency
Every 30 minutes
Estimated price
$10 - $20
Schedules at
mta.info
Off-peak at station
$10 - $12
Off-peak onboard
$16 - $17
Onboard
$14 - $20
At station
$10 - $15
MTA
Website
mta.info
Subway from 125 St to 68 St - Hunter College
Ave. Duration
11 min
Frequency
Every 5 minutes
Estimated price
$3
Website
mta.info
Subway from Lexington Av/63 St to Jackson Hts - Roosevelt Av
Ave. Duration
12 min
Frequency
Every 5 minutes
Estimated price
$3
Website
mta.info
Subway from 125 St to Grand Central - 42 St
Ave. Duration
17 min
Frequency
Every 5 minutes
Estimated price
$3
Website
mta.info
Subway from 125 St to 34 St - Penn Station
Ave. Duration
16 min
Frequency
Every 5 minutes
Estimated price
$3
Website
mta.info
Long Island Rail Road
Phone
+1 718-217-5477
Website
mta.info
Train from Penn Station to Jamaica
Ave. Duration
21 min
Frequency
Every 15 minutes
Estimated price
$4 - $6
Website
LIRR
Amtrak Acela Express

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak Acela Express
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from New York Penn Station to Philadelphia 30th Street Station
Ave. Duration
1 h 8 min
Frequency
Every 30 minutes
Estimated price
$75 - $210
Website
amtrak.com
Business Seat
$75 - $180
First Class Seat
$150 - $210
Bus operators
OurBus
Phone
+1 844-800-6828
Website
ourbus.com
Bus from New York, NY to Syracuse, NY
Ave. Duration
4 h 35 min
Frequency
5 times a week
Estimated price
$16 - $35
Book at
ourbus.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from New York, Ny to Syracuse, Ny
Ave. Duration
4 h 55 min
Frequency
Every 3 hours
Estimated price
$29 - $70
Website
greyhound.com
Economy
$29 - $50
Flexible
$55 - $70
Trailways New York
Phone
(800) 858-8555
Website
trailwaysny.com
Bus from Elmira, NY to Destiny USA
Ave. Duration
2 h 15 min
Frequency
Once daily
Estimated price
$21 - $30
Book at
trailwaysny.com

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

Yes, the driving distance between Harlem-125th St. to Syracuse is 255 miles. It takes approximately 4 h 24 min to drive from Harlem-125th St. to Syracuse.

Get driving directions

Delta offers flights from New York La Guardia Airport to Syracuse Airport.

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There are 74+ hotels available in Syracuse. Prices start at $62 USD per night.

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