There are 7 ways to get from Hannibal to Chicago by taxi, plane, train (Amtrak), car, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi to Quincy Regional Airport, fly to Chicago O'Hare International Airport
best- Take the taxi from Hannibal to Quincy Regional Airport (UIN)taxi
- Fly from Quincy Regional Airport (UIN) to Chicago O'Hare International Airport (ORD)plane UIN - ORD
2h 53m$113–209Drive 295.5 mi
cheapest- Drive from Hannibal to Chicagocar 295.5 mi
5h 10m$54–78Train (Amtrak)
- Take the train from Quincy Amtrak Station to Chicago Union Stationtrain Carl Sandburg / ...
4h 51m$129–236Drive to Burlington Municipal Airport, fly to Chicago O'Hare International Airport
- Drive from Hannibal to Burlington Municipal Airport (BRL)car
- Fly from Burlington Municipal Airport (BRL) to Chicago O'Hare International Airport (ORD)plane BRL - ORD
4h 24m$59–149Shuttle to Lambert–St. Louis International Airport, fly to Chicago Midway International Airport
- Take a shuttle bus from Hannibal to St. Louis
- Fly from Lambert–St. Louis International Airport (STL) to Chicago Midway International Airport (MDW)plane STL - MDW
5h 2m$111–647Shuttle to Columbia Regional Airport, fly to Chicago O'Hare International Airport
- Take a shuttle bus from Hannibal to Columbia
- Fly from Columbia Regional Airport (COU) to Chicago O'Hare International Airport (ORD)plane COU - ORD
5h 21m$113–338Shuttle to Lambert–St. Louis International Airport, fly to Chicago O'Hare International Airport
- Take a shuttle bus from Hannibal to St. Louis
- Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)plane STL - ORD
5h 25m$286–467
Quincy Regional Airport (UIN) to Chicago O'Hare International Airport (ORD) flights
Questions & Answers
The cheapest way to get from Hannibal to Chicago is to drive which costs $50 - $80 and takes 5h 10m.
The fastest way to get from Hannibal to Chicago is to taxi and fly which takes 2h 53m and costs $110 - $210.
The distance between Hannibal and Chicago is 269 miles. The road distance is 297.2 miles.
The best way to get from Hannibal to Chicago without a car is to train which takes 4h 51m and costs $120 - $240.
It takes approximately 2h 53m to get from Hannibal to Chicago, including transfers.
Yes, the driving distance between Hannibal to Chicago is 297 miles. It takes approximately 5h 10m to drive from Hannibal to Chicago.
There are 1304+ hotels available in Chicago.
What companies run services between Hannibal, MO, USA and Chicago, IL, USA?
Amtrak operates a train from Quincy Amtrak Station to Chicago Union Station twice daily. Tickets cost $65–160 and the journey takes 4h 21m.
- Website
- aa.com
Flights from Columbia Regional Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $30–230
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $45–320
- Website
- united.com
Flights from Columbia Regional Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $30–230
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $45–320
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 7m
- When
- Every day
- Estimated price
- $75–600
- Website
- contouraviation.com
Flights from Quincy Regional Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $40–120
Flights from Burlington Municipal Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $40–120
- Website
- gojetairlines.com
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $45–320
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Quincy Amtrak Station to Chicago Union Station
- Ave. Duration
- 4h 21m
- Frequency
- Twice daily
- Estimated price
- $65–160
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-888-875-6287
- Website
- oatstransit.org
Shuttle from Hannibal to St. Louis
- Ave. Duration
- 1h 51m
- Frequency
- Twice a week
- Estimated price
- $4–7
- Website
- https://www.oatstransit.org
- Schedules at
- https://www.oatstransit.org/schedules
Shuttle from Hannibal to Columbia
- Ave. Duration
- 1h 45m
- Frequency
- Twice a week
- Estimated price
- $4–6
- Website
- https://www.oatstransit.org
- Schedules at
- https://www.oatstransit.org/schedules
- Ave. Duration
- 30 min
- Estimated price
- $70–85
Quincy Premium Transportation
- Phone
- +1 217-901-7433
- Website
- quincypremiumtransportation.com
Diamond Cab
- Phone
- +1-217-222-6700
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