From Hammersmith Broadway bus to Southampton City Centre, Coach Station. 2 h 5 min £10. From Hammersmith (Dist&Picc Line) Underground Station Tube to Embankment Underground Station, walk to London Waterloo, then train to Southampton Central. 2 h 17 min £28. From Hammersmith (Dist&Picc Line) Underground Station Tube to London Victoria then train to Southampton Central. 3 h 37 min £58. From Hammersmith drive to Southampton. 1 h 20 min £14.
National Express operates a bus from Hammersmith to Southampton 4 times a day. Tickets cost $10 - $14 and the journey takes 2 h 5 min. Alternatively, London Underground (Tube) operates a train from Hammersmith to Southampton every 5 minutes. Tickets cost $3 - $5 and the journey takes 20 min. South Western Railway also services this route hourly.