Rome2Rio

How to get fromGuelph to Iowaby train, plane, bus, car, shuttle or bus (Flixbus, Greyhound)

Find Transport to Iowa

See all options

There are 10 ways to get from Guelph to Iowa by train, plane, bus, car, shuttle, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Toronto Pearson International Airport, fly to Des Moines

    best
    1. Take the train from Guelph Central GO to Bramalea GOtrain train
    2. Fly from Toronto Pearson International Airport (YYZ) to Des Moines (DSM)plane plane YYZ - DSM
    8h 10m
    $158–784

  2. Train to Toronto Pearson International Airport, fly to Quad City International Airport

    cheapest
    1. Take the train from Guelph Central GO to Bramalea GOtrain train
    2. Fly from Toronto Pearson International Airport (YYZ) to Quad City International Airport (MLI)plane plane YYZ - MLI
    9h 14m
    $63–325

  3. Train, bus

    1. Take the train from Guelph to Sarniatrain train
    2. Take the train from Port Huron Station to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    20h 54m
    $184–420

  4. Train, bus via London

    1. Take the train from Guelph to Londontrain train
    2. Take the bus from London to Detroit Bus Stationbus bus
    3. Take the bus from Detroit Bus Station to Chicago Bus Stationbus bus
    4. Take the bus from Chicago Bus Station to Des Moinesbus bus
    23h 43m
    $137–335

  5. Drive 783.4 mi

    1. Drive from Guelph to Des Moinescar car 783.4 mi
    13h 7m
    $180–259

  6. Train to Toronto Pearson International Airport, fly to Waterloo Municipal Airport

    1. Take the train from Guelph Central GO to Bramalea GOtrain train
    2. Fly from Toronto Pearson International Airport (YYZ) to Waterloo Municipal Airport (ALO)plane plane YYZ - ALO
    8h 19m
    $83–354

  7. Train to Toronto Island Airport, fly to Quad City International Airport

    1. Take the train from Guelph Central GO to Union Station GOtrain train
    2. Fly from Toronto Island Airport (YTZ) to Quad City International Airport (MLI)plane plane YTZ - MLI
    10h 13m
    $67–345

  8. Train, shuttle to Detroit, fly to Des Moines

    1. Take the train from Guelph to Londontrain train
    2. Take a shuttle bus from London, ON - 105, Wharncliffe Road South, Manor Park to Detroit Airportshuttle bus
    3. Fly from Detroit (DTW) to Des Moines (DSM)plane plane DTW - DSM
    10h 18m
    $190–899

  9. Train to Toronto Pearson International Airport, fly to The Eastern Iowa Airport, bus

    1. Take the train from Guelph Central GO to Bramalea GOtrain train
    2. Fly from Toronto Pearson International Airport (YYZ) to The Eastern Iowa Airport (CID)plane plane YYZ - CID
    3. Take the bus from GTC Bay 9 to Court St Transportation Centerbus bus
    10h 49m

  10. Bus

    1. Take the bus from Kitchener to Detroit Bus Stationbus bus
    2. Take the bus from Detroit Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    24h 15m
    $136–281

Toronto Pearson International Airport (YYZ) to Des Moines (DSM) flights

Calendar107Weekly Planes
Duration5h 24mAverage Duration
Ticket$135Cheapest Price
See schedules

Questions & Answers

What companies run services between Guelph, ON, Canada and Iowa, USA?

You can take a bus from Guelph Central GO Bus to Des Moines via University of Waterloo Terminal, Kitchener GO Bus, Kitchener, Detroit Bus Station, Chicago Bus Station, and Des Moines in around 24h 15m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Trips from Guelph

Trips to Iowa

Popular routes