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How to get fromGuelph to Indianaby train, plane, bus, train (Amtrak), car, shuttle, bus (Flixbus), or bus (Flixbus, Greyhound)

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There are 10 ways to get from Guelph to Indiana by train, plane, bus, train (Amtrak), car, shuttle, bus (Flixbus), or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Toronto Pearson International Airport, fly to Indianapolis

    best
    1. Take the train from Guelph Central GO to Bramalea GOtrain train
    2. Fly from Toronto Pearson International Airport (YYZ) to Indianapolis (IND)plane plane YYZ - IND
    6h 24m
    $413–1,015

  2. Bus via London

    cheapest
    1. Take the bus from Guelph to Londonbus bus
    2. Take the bus from London to Detroit Bus Stationbus bus
    3. Take the bus from Detroit, MI to Indianapolis, INbus bus
    13h 5m
    $60–126

  3. Train, bus

    1. Take the train from Guelph to Londontrain train
    2. Take the train from London to Windsortrain train
    3. Take the bus from Detroit, MI to Indianapolis, INbus bus
    11h 48m
    $77–411

  4. Train

    1. Take the train from Guelph to Sarniatrain train
    2. Take the train from Port Huron Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Indianapolistrain train
    17h 8m
    $197–522

  5. Drive 460.4 mi

    1. Drive from Guelph to Indianapoliscar car 460.4 mi
    8h 14m
    $106–153

  6. Train to Toronto Pearson International Airport, fly to Chicago O'Hare International Airport, train

    1. Take the train from Guelph Central GO to Bramalea GOtrain train
    2. Fly from Toronto Pearson International Airport (YYZ) to Chicago O'Hare International Airport (ORD)plane plane YYZ - ORD
    3. Take the train from Van Buren St. to Gary Metro Centertrain train
    7h 33m
    $350–1,127

  7. Train to Toronto Island Airport, fly to Chicago O'Hare International Airport, train

    1. Take the train from Guelph Central GO to Union Station GOtrain train
    2. Fly from Toronto Island Airport (YTZ) to Chicago O'Hare International Airport (ORD)plane plane YTZ - ORD
    3. Take the train from Van Buren St. to Gary Metro Centertrain train
    7h 37m
    $200–1,327

  8. Train to Toronto Island Airport, fly to Chicago Midway International Airport, train

    1. Take the train from Guelph Central GO to Union Station GOtrain train
    2. Fly from Toronto Island Airport (YTZ) to Chicago Midway International Airport (MDW)plane plane YTZ - MDW
    3. Take the train from Van Buren St. to Gary Metro Centertrain train
    7h 25m
    $160–457

  9. Train, shuttle to Buffalo Niagara International Airport, fly to Chicago Midway International Airport

    1. Take the train from Guelph Central GO to Bramalea GOtrain train
    2. Take a shuttle bus from Pearson International Airport Terminal 1 to Buffalo Airportshuttle bus
    3. Fly from Buffalo Niagara International Airport (BUF) to Chicago Midway International Airport (MDW)plane plane BUF - MDW
    4. Take the train from Van Buren St. to Gary Metro Centertrain train
    8h 37m
    $270–517

  10. Bus

    1. Take the bus from Kitchener to Detroit Bus Stationbus bus FlixBus N2710
    2. Take the bus from Detroit Bus Station to Indianapolis Union Stationbus bus Greyhound US0112
    13h 42m
    $77–144

Guelph to Indiana by train, car, and bus

Calendar7Weekly Services
Duration11h 48mAverage Duration
Ticket$77Cheapest Price
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Questions & Answers

Map of how to get from Guelph to Indiana.ExpandLaunch map view
  • Distance: 494.1 mi
  • Duration: 6h 24m

What companies run services between Guelph, ON, Canada and Indiana, USA?

You can take a train from Guelph to Indianapolis via Sarnia, Port Huron Station, and Chicago Union Station in around 17h 8m. Alternatively, you can take a bus from Guelph to Indianapolis, IN via London and Detroit, MI in around 13h 5m.

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