Rome2Rio

How to get fromGuelph to Chicago Loopby train, plane, train (Amtrak), bus (Flixbus, Greyhound), car, bus, or bus (Flixbus, Amtrak)

Find Transport to Chicago Loop

See all options

There are 8 ways to get from Guelph to Chicago Loop by train, plane, train (Amtrak), bus (Flixbus, Greyhound), car, bus, or bus (Flixbus, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Toronto Pearson International Airport, fly to Chicago O'Hare International Airport

    best
    1. Take the train from Guelph Central GO to Bramalea GOtrain train
    2. Fly from Toronto Pearson International Airport (YYZ) to Chicago O'Hare International Airport (ORD)plane plane YYZ - ORD
    6h 14m
    $402–967

  2. Bus

    cheapest
    1. Take the bus from Kitchener to Detroit Bus Stationbus bus FlixBus N2710
    2. Take the bus from Detroit Bus Station to Chicago Bus Stationbus bus Greyhound US0160
    14h 24m
    $78–127

  3. Train

    1. Take the train from Guelph to Sarniatrain train VIA Rail
    2. Take the train from Port Huron Station to Chicago Union Stationtrain train Blue Water
    11h 14m
    $111–366

  4. Drive  466.3 mi

    1. Drive from Guelph to Chicago Loopcar car 466.3 mi
    7h 54m
    $107–155

  5. Train to Toronto Island Airport, fly to Chicago O'Hare International Airport

    1. Take the train from Guelph Central GO to Union Station GOtrain train
    2. Fly from Toronto Island Airport (YTZ) to Chicago O'Hare International Airport (ORD)plane plane YTZ - ORD
    6h 16m
    $192–1,418

  6. Bus, bus to Buffalo Niagara International Airport, fly to Chicago Midway International Airport

    1. Take the bus from Guelph Central GO Bus to Winston Churchill Transitway Stationbus bus
    2. Take the bus from Mississauga to Buffalobus bus
    3. Fly from Buffalo Niagara International Airport (BUF) to Chicago Midway International Airport (MDW)plane plane BUF - MDW
    8h 51m
    $191–384

  7. Bus, bus to Buffalo Niagara International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Guelph Central GO Bus to Winston Churchill Transitway Stationbus bus
    2. Take the bus from Mississauga to Buffalobus bus
    3. Fly from Buffalo Niagara International Airport (BUF) to Chicago O'Hare International Airport (ORD)plane plane BUF - ORD
    9h 3m
    $201–374

  8. Bus via Dearborn

    1. Take the bus from Kitchener to Detroit Bus Stationbus bus FlixBus N2710
    2. Take the bus from Dearborn to Chicago Union Stationbus bus Amtrak Thruway Connecting Service
    14h 31m
    $102–151

Guelph to Chicago Loop by train and car

Calendar7Weekly Services
Duration11h 14mAverage Duration
Ticket$111Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Guelph to Chicago Loop.ExpandLaunch map view
  • Distance: 492.5 mi
  • Duration: 6h 14m

What companies run services between Guelph, ON, Canada and Chicago Loop, IL, USA?

You can take a train from Guelph to Chicago Union Station via Sarnia and Port Huron Station in around 11h 14m. Alternatively, you can take a bus from Guelph Central GO Bus to Washington & Lasalle via Victoria / Bingemans Centre Dr., Kitchener, Detroit Bus Station, Chicago Bus Station, and Jefferson & Harrison in around 14h 24m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There