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How to get fromGuaymas to Weslacoby bus, plane, car or train

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There are 6 ways to get from Guaymas to Weslaco by bus, plane, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Ciudad Obregón International Airport, fly, drive

    best
    1. Take the bus from Guaymas to Ciudad Obregónbus
    2. Fly from Ciudad Obregón International Airport (CEN) to General Lucio Blanco International Airport (REX)planeCEN - REX
    3. Drive from General Lucio Blanco International Airport (REX) to Weslacocar
    9h 3m
    $187–548
  2. Bus

    cheapest
    1. Take the bus from Empalme to Monterreybus
    2. Take the bus from Monterrey to McAllen Central Stationbus
    39h 53m
    $143–390
  3. Bus via Mazatlán

    1. Take the bus from Guaymas to Mazatlánbus
    2. Take the bus from Mazatlán to Durangobus
    3. Take the bus from Durango to Reynosabus
    30h 13m
    $184–311
  4. Bus, train

    1. Take the bus from Guaymas to Nogalesbus
    2. Take the bus from Nogales to Tucsonbus
    3. Take the train from Tucson Amtrak Station to San Antonio Amtrak Stationtrain
    4. Take the bus from San Antonio to McAllen Central Stationbus
    34h 30m
    $207–381
  5. Drive 1,139.3 mi

    1. Drive from Guaymas to Weslacocar1,139.3 mi
    20h 27m
    $208–301
  6. Bus to Hermosillo International Airport, fly, drive

    1. Take the bus from Guaymas to Hermosillobus
    2. Fly from Hermosillo International Airport (HMO) to General Lucio Blanco International Airport (REX)planeHMO - REX
    3. Drive from General Lucio Blanco International Airport (REX) to Weslacocar
    11h 3m
    $172–470

Ciudad Obregón International Airport (CEN) to General Lucio Blanco International Airport (REX) flights

Calendar9Weekly Planes
Duration5h 42mAverage Duration
Ticket$175Cheapest Price
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Questions & Answers

What companies run services between Guaymas, Mexico and Weslaco, TX, USA?

You can take a bus from Guaymas to STC Mid Valley Campus via Mazatlán, Durango, Reynosa, and McAllen Central Station in around 30h 13m.

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