There are 6 ways to get from Guaymas to Weslaco by bus, plane, car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Ciudad Obregón International Airport, fly, drive
best- Take the bus from Guaymas to Ciudad Obregón
- Fly from Ciudad Obregón International Airport (CEN) to General Lucio Blanco International Airport (REX)CEN - REX
- Drive from General Lucio Blanco International Airport (REX) to Weslaco
9h 3m$187–548Bus
cheapest- Take the bus from Empalme to Monterrey
- Take the bus from Monterrey to McAllen Central Station
39h 53m$143–390Bus via Mazatlán
- Take the bus from Guaymas to Mazatlán
- Take the bus from Mazatlán to Durango
- Take the bus from Durango to Reynosa
30h 13m$184–311Bus, train
- Take the bus from Guaymas to Nogales
- Take the bus from Nogales to Tucson
- Take the train from Tucson Amtrak Station to San Antonio Amtrak Station
- Take the bus from San Antonio to McAllen Central Station
34h 30m$207–381Drive 1,139.3 mi
- Drive from Guaymas to Weslaco1,139.3 mi
20h 27m$208–301Bus to Hermosillo International Airport, fly, drive
- Take the bus from Guaymas to Hermosillo
- Fly from Hermosillo International Airport (HMO) to General Lucio Blanco International Airport (REX)HMO - REX
- Drive from General Lucio Blanco International Airport (REX) to Weslaco
11h 3m$172–470
Ciudad Obregón International Airport (CEN) to General Lucio Blanco International Airport (REX) flights
Questions & Answers
The cheapest way to get from Guaymas to Weslaco is to bus via Mazatlán which costs $180 - $320 and takes 30h 13m.
The fastest way to get from Guaymas to Weslaco is to bus and fly and drive which takes 9h 3m and costs $180 - $550.
No, there is no direct bus from Guaymas to Weslaco. However, there are services departing from Guaymas and arriving at STC Mid Valley Campus via Mazatlán, Durango, Reynosa and McAllen Central Station. The journey, including transfers, takes approximately 30h 13m.
The distance between Guaymas and Weslaco is 840 miles. The road distance is 1146 miles.
The best way to get from Guaymas to Weslaco without a car is to bus via Mazatlán which takes 30h 13m and costs $180 - $320.
It takes approximately 9h 3m to get from Guaymas to Weslaco, including transfers.
Guaymas to Weslaco bus services, operated by Tufesa Mexico, depart from Guaymas station.
Guaymas to Weslaco bus services, operated by Tufesa Mexico, arrive at Mazatlán station.
Weslaco is 1h ahead of Guaymas. It is currently 6:15 PM in Guaymas and 7:15 PM in Weslaco.
Yes, the driving distance between Guaymas to Weslaco is 1146 miles. It takes approximately 20h 27m to drive from Guaymas to Weslaco.
What companies run services between Guaymas, Mexico and Weslaco, TX, USA?
You can take a bus from Guaymas to STC Mid Valley Campus via Mazatlán, Durango, Reynosa, and McAllen Central Station in around 30h 13m.
- Website
- vivaaerobus.com
Flights from Ciudad Obregón International Airport to General Lucio Blanco International Airport via Mexico City Santa Lucia Apt
- Ave. Duration
- 6h 15m
- When
- Monday, Friday, and Sunday
- Estimated price
- $170–500
Flights from Hermosillo International Airport to General Lucio Blanco International Airport via Mexico City Santa Lucia Apt
- Ave. Duration
- 14h 20m
- When
- Tuesday
- Estimated price
- $150–430
Flights from Hermosillo International Airport to General Lucio Blanco International Airport via Mexico City
- Ave. Duration
- 10h 14m
- When
- Every day
- Estimated price
- $140–650
Flights from Hermosillo International Airport to General Lucio Blanco International Airport via Monterrey, Mexico City Santa Lucia Apt
- Ave. Duration
- 14h 25m
- When
- Tuesday
- Estimated price
- $160–440
- Website
- aeromexico.com
Flights from Ciudad Obregón International Airport to General Lucio Blanco International Airport via Mexico City
- Ave. Duration
- 5h 9m
- When
- Monday to Saturday
- Estimated price
- $200–1,000
Flights from Hermosillo International Airport to General Lucio Blanco International Airport via Mexico City
- Ave. Duration
- 7h 20m
- When
- Every day
- Estimated price
- $180–900
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Tucson Amtrak Station to San Antonio Amtrak Station
- Ave. Duration
- 18h 7m
- Frequency
- 6 times a week
- Estimated price
- $100–190
- Website
- https://www.amtrak.com/home.html
- Phone
- +52 644 410 2444
- atencionaclientes@tufesa.com.mx
- Website
- tufesa.com.mx
Bus from Guaymas to Ciudad Obregón
- Ave. Duration
- 2h
- Frequency
- Every 3 hours
- Estimated price
- $8–21
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $8–21
- Titanium
- $9–21
Bus from Guaymas to Mazatlán
- Ave. Duration
- 10h 56m
- Frequency
- Every 4 hours
- Estimated price
- $50–75
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $50–75
- Titanium
- $55–70
Bus from Guaymas to Nogales
- Ave. Duration
- 5h 22m
- Frequency
- Once daily
- Estimated price
- $27–40
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $27–40
- Titanium
- $30–40
Bus from Nogales to Tucson
- Ave. Duration
- 1h 22m
- Frequency
- Every 4 hours
- Estimated price
- $6–19
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $6–19
- Titanium
- $7–19
Bus from Guaymas to Hermosillo
- Ave. Duration
- 1h 57m
- Frequency
- Every 4 hours
- Estimated price
- $9–22
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $9–21
- Titanium
- $10–22
- Phone
- +52 55 5141 4300
- contacto@odm.com.mx
- Website
- odm.com.mx
Bus from Guaymas to Ciudad Obregón
- Ave. Duration
- 2h
- Frequency
- 5 times a day
- Estimated price
- $13–35
- Schedules at
- odm.com.mx
- Book at
- odm.com.mx
Bus from Guaymas to Mazatlán
- Ave. Duration
- 13h 1m
- Frequency
- 3 times a day
- Estimated price
- $65–130
- Schedules at
- odm.com.mx
- Book at
- odm.com.mx
Bus from Mazatlán to Durango
- Ave. Duration
- 2h 45m
- Frequency
- 4 times a day
- Estimated price
- $35–55
- Schedules at
- odm.com.mx
- Book at
- odm.com.mx
Bus from Durango to Reynosa
- Ave. Duration
- 11h 45m
- Frequency
- Twice daily
- Estimated price
- $95–130
- Schedules at
- odm.com.mx
- Book at
- odm.com.mx
Bus from Guaymas to Nogales
- Ave. Duration
- 6h
- Frequency
- Every 4 hours
- Estimated price
- $30–75
- Schedules at
- odm.com.mx
- Book at
- odm.com.mx
- Phone
- +52 55 4440 3187
- contacto@geb.mx
- Website
- autobusesaguacaliente.mx
Bus from Guaymas to Ciudad Obregón
- Ave. Duration
- 1h 45m
- Frequency
- 4 times a day
- Estimated price
- $8–13
- Schedules at
- autobusesaguacaliente.mx
- Book at
- autobusesaguacaliente.mx
- Phone
- +52 55 4440 3187
- servicioalcliente@geb.mx
- Website
- autobuseselite.com.mx
Bus from Guaymas to Ciudad Obregón
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $13–30
- Schedules at
- autobuseselite.com.mx
- Book at
- autobuseselite.com.mx
- Phone
- +52 55 4440 3187
- servicioalcliente@geb.mx
- Website
- chihuahuenses.com.mx
Bus from Guaymas to Ciudad Obregón
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $13–28
- Schedules at
- chihuahuenses.com.mx
- Book at
- chihuahuenses.com.mx
- Phone
- +52 55 4440 3187
- servicioalcliente@geb.mx
- Website
- futura.com.mx
Bus from Guaymas to Ciudad Obregón
- Ave. Duration
- 2h
- Frequency
- Twice daily
- Estimated price
- $13–26
- Schedules at
- futura.com.mx
- Book at
- futura.com.mx
Bus from Empalme to Monterrey
- Ave. Duration
- 31h 9m
- Frequency
- Once daily
- Estimated price
- $110–320
- Schedules at
- futura.com.mx
- Book at
- futura.com.mx
- Phone
- +52 800 624 6618
- clientes@albatrosautobuses.mx
- Website
- albatrosautobuses.mx
Bus from Guaymas to Ciudad Obregón
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $7–11
- Schedules at
- albatrosautobuses.mx
- Book at
- albatrosautobuses.mx
- Phone
- +1 800-923-1799
- contactus@omexusa.net
- Website
- omnibusexpress.com
Bus from San Antonio to McAllen Central Station
- Ave. Duration
- 4h 1m
- Frequency
- Once daily
- Estimated price
- $60–80
- Schedules at
- omnibusexpress.com
- Phone
- +1 800 923 1799
- contactus@omexusa.net
- Website
- omnibusexpress.com
Bus from Monterrey to McAllen Central Station
- Ave. Duration
- 5h
- Frequency
- Every 4 hours
- Estimated price
- $30–50
- Schedules at
- omnibusexpress.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
There are 128+ hotels available in Weslaco.



































