There are 5 ways to get from Guayaquil to Cali by plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  2 h 29 min

  1. Fly from Guayaquil (GYE) to Cali (CLO) GYE - CLO

$200 - $470

Cheapest option

Bus Bolivariano  •  27 h 35 min

  1. Take the bus from Guayaquil to Quito Terminal Quitumbe
  2. Take the bus from Quito to Cali Via Bogota

$44 - $64

3 alternative options

Bus Expreso Internacional Ormeño  •  22 h 10 min

  1. Take the bus from Guayaquil to Cali Via Bogota

$71 - $94

Bus Cruz del Sur  •  31 h 48 min

  1. Take the bus from Guayaquil to Santo Domingo de los Colorados
  2. Take the bus from Santo Domingo de los Tsáchilas to Quito - Terminal Quitumbe
  3. Take the bus from Quito Terminal Quitumbe to Cali

$113 - $168

Drive  •  19 h 51 min

  1. Drive from Guayaquil to Cali 756.5 miles

$75 - $120

Questions & Answers

The cheapest way to get from Guayaquil to Cali is to bus which costs $40 - $65 and takes 27 h 35 min.

More details

The quickest way to get from Guayaquil to Cali is to fly which costs $200 - $470 and takes 2 h 29 min.

More details

The distance between Guayaquil and Cali is 732 km. The road distance is 1210.4 km.

Get driving directions

It takes approximately 2 h 29 min to get from Guayaquil to Cali, including transfers.

More details

No, there is no direct bus from Guayaquil to Cali. However, there are services departing from Guayaquil and arriving at Cali via Quito. The journey, including transfers, takes approximately 27 h 35 min.

More details

Yes, the driving distance between Guayaquil to Cali is 1210 km. It takes approximately 19 h 51 min to drive from Guayaquil to Cali.

Get driving directions

Map of how to get from Guayaquil to Cali.
Launch map view
  • Distance: 457.3 miles
  • Duration: 2 h 29 min

What companies run services between Guayaquil, Ecuador and Cali, Colombia?

Avianca - Aerovías del Continente Americano S.A. flies from Guayaquil to Cali twice daily. Alternatively, Expreso Internacional Ormeño operates a bus from Guayaquil to Cali 3 times a week. Tickets cost $50 - $70 and the journey takes 22 h.

Airlines
Avianca - Aerovías del Continente Americano S.A.
Website
avianca.com
Flights from Guayaquil to Cali
Ave. Duration
1 h 30 min
When
Every day
Estimated price
$370 - $900
Flights from Guayaquil to Cali via Bogota
Ave. Duration
3 h 48 min
When
Monday to Saturday
Estimated price
$370 - $900
Bus operators
Cooperativa de Transportes Aerotaxi
Phone
593 99 195 2081
Email
transportesaerotaxi@yahoo.com
Website
coop_transporte_aerotaxi.amawebs.com
Bus from Guayaquil to Quito Terminal Quitumbe
Ave. Duration
8 h 5 min
Frequency
Every 2 hours
Estimated price
$14
Schedules at
coop_transporte_aerotaxi.amawebs.com
Book at
andestransit.com
Cooperativa de Transportes Zaracay
Phone
(+593)-0236547894
Website
transporteszaracay.com.ec
Bus from Guayaquil to Santo Domingo de los Colorados
Ave. Duration
5 h
Frequency
Hourly
Estimated price
$7
Schedules at
transporteszaracay.com.ec
Book at
andestransit.com
Panamericana Internacional
Phone
+593 (2) 2557133 / 2557134
Email
info@panamericana.ec
Website
panamericana.ec
Bus from Santo Domingo de los Tsáchilas to Quito - Terminal Quitumbe
Ave. Duration
2 h 8 min
Frequency
Hourly
Estimated price
$6 - $9
Schedules at
panamericana.ec
Transportes Occidentales
Phone
+593 2-303-4291
Email
sistemas@transportesoccidentales.com
Website
transportesoccidentales.com.ec
Bus from Santo Domingo de los Tsáchilas to Quito - Terminal Quitumbe
Ave. Duration
2 h 18 min
Frequency
5 times a day
Estimated price
$11
Schedules at
transportesoccidentales.com.ec
Book at
andestransit.com
Reina del Camino
Phone
042130757 - 042130030, 023824850 - 023824875
Email
denuncias@reinadelcamino.ec
Website
facebook.com
Bus from Santo Domingo to Quito Terminal Quitumbe
Ave. Duration
2 h 23 min
Frequency
3 times a day
Estimated price
$9
Schedules at
busbud.com
Cruz del Sur
Phone
+51 1 311-5050
Website
cruzdelsur.com.pe
Bus from Quito Terminal Quitumbe to Cali
Ave. Duration
23 h 10 min
Frequency
Twice a week
Estimated price
$100 - $150
Schedules at
cruzdelsur.com.pe
Book at
cruzdelsur.com.pe

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