There are 6 ways to get from Guayaquil to Cali by plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  2 h 29 min

  1. Fly from Guayaquil (GYE) to Cali (CLO) GYE - CLO

$193 - $462

Cheapest option

Bus Expreso Internacional Ormeño  •  25 h 28 min

  1. Take the bus from Guayaquil to Cali

$65 - $92

4 alternative options

Bus via Santo Domingo de los Colorados  •  22 h 45 min

  1. Take the bus from Guayaquil to Santo Domingo de los Colorados
  2. Take the bus from Santo Domingo de los Colorados to Quito - Terminal Quitumbe
  3. Take the bus from Quito Terminal Quitumbe to Cali

$113 - $167

Bus  •  23 h 56 min

  1. Take the bus from Guayaquil to Quito Terminal Quitumbe
  2. Take the bus from Quito Terminal Quitumbe to Cali

$114 - $164

Bus Expreso Internacional Ormeño Perú  •  26 h 28 min

  1. Take the bus from Guayaquil Terminal, Avenida Benjamín Rosales, La Garzota, Tarqui, Guayaquil, Guayas, Ecuador to Cali

Drive  •  19 h 51 min

  1. Drive from Guayaquil to Cali 756.5 miles

$75 - $120

What companies run services between Guayaquil, Ecuador and Cali, Colombia?

Avianca - Aerovías del Continente Americano S.A. flies from Guayaquil to Cali twice daily. Alternatively, you can take a bus from Guayaquil to Cali via Santo Domingo de los Colorados, Santo Domingo de los Colorados, Quito - Terminal Quitumbe, and Quito Terminal Quitumbe in around 22 h 45 min.

Airlines
Avianca - Aerovías del Continente Americano S.A.
Website
avianca.com
Flights from Guayaquil to Cali
Ave. Duration
1 h 30 min
When
Every day
Estimated price
$370 - $900
Flights from Guayaquil to Cali via Bogota
Ave. Duration
3 h 48 min
When
Monday to Saturday
Estimated price
$370 - $900
Bus operators
Cooperativa de Transportes Zaracay
Phone
(+593)-0236547894
Website
transporteszaracay.com.ec
Bus from Guayaquil to Santo Domingo de los Colorados
Ave. Duration
5 h
Frequency
Hourly
Estimated price
$7
Schedules at
transporteszaracay.com.ec
Book at
andestransit.com
Panamericana Internacional
Phone
+593 (2) 2557133 / 2557134
Email
info@panamericana.ec
Website
panamericana.ec
Bus from Santo Domingo de los Colorados to Quito - Terminal Quitumbe
Ave. Duration
1 h 45 min
Frequency
Every 10 minutes
Estimated price
$6 - $10
Schedules at
panamericana.ec
Cruz del Sur
Phone
+51 1 311-5050
Website
cruzdelsur.com.pe
Bus from Quito Terminal Quitumbe to Cali
Ave. Duration
14 h 51 min
Frequency
Twice a week
Estimated price
$100 - $150
Schedules at
cruzdelsur.com.pe
Book at
cruzdelsur.com.pe
Cooperativa de Transportes Aerotaxi
Phone
593 99 195 2081
Email
transportesaerotaxi@yahoo.com
Website
coop_transporte_aerotaxi.amawebs.com
Bus from Guayaquil to Quito Terminal Quitumbe
Ave. Duration
8 h 5 min
Frequency
Every 2 hours
Estimated price
$14
Schedules at
coop_transporte_aerotaxi.amawebs.com
Book at
andestransit.com
Expreso Internacional Ormeño Perú
Website
grupo-ormeno.com.co
Bus from Guayaquil Terminal, Avenida Benjamín Rosales, La Garzota, Tarqui, Guayaquil, Guayas, Ecuador to Cali
Ave. Duration
26 h
Frequency
3 times a week
Schedules at
es-la.facebook.com

Want to know more about travelling around the world?

Rome2rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including How to get from JFK to New York City, French strikes 2018: What are my alternative transport options? and How do I get from Sydney to Melbourne - to help you get the most out of your next trip.

Questions & Answers

The distance between Guayaquil and Cali is 732 km. The road distance is 1210 km.

The cheapest way to get from Guayaquil to Cali is to bus which costs $65 - $95 and takes 25 h 28 min.

The quickest way to get from Guayaquil to Cali is to fly which takes 2 h 29 min and costs $190 - $470.

No, there is no direct bus from Guayaquil to Cali. However, there are services departing from Guayaquil and arriving at Cali via Santo Domingo de los Colorados and Quito Terminal Quitumbe. The journey, including transfers, takes approximately 22 h 45 min.

It takes approximately 2 h 29 min to get from Guayaquil to Cali, including transfers.