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There are 5 ways to get from Guayaquil to Cali by plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  2 h 29 min

  1. Fly from Guayaquil (GYE) to Cali (CLO) GYE - CLO

$200 - $470

Cheapest option

Bus Bolivariano  •  27 h 35 min

  1. Take the bus from Guayaquil to Quito Terminal Quitumbe
  2. Take the bus from Quito to Cali Via Bogota

$44 - $59

3 alternative options

Bus Expreso Internacional Ormeño  •  22 h 10 min

  1. Take the bus from Guayaquil to Cali Via Bogota

$71 - $94

Bus Omega  •  22 h 10 min

  1. Take the bus from Guayaquil to Santo Domingo de los Colorados
  2. Take the bus from Santo Domingo de los Colorados to Quito - Terminal Quitumbe
  3. Take the bus from Quito to Cali

$48 - $72

Drive  •  19 h 51 min

  1. Drive from Guayaquil to Cali 756.5 miles

$75 - $120

Questions & Answers

The cheapest way to get from Guayaquil to Cali is to bus which costs $40 - $60 and takes 27 h 35 min.

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The quickest way to get from Guayaquil to Cali is to fly which costs $200 - $470 and takes 2 h 29 min.

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No, there is no direct bus from Guayaquil to Cali. However, there are services departing from Guayaquil and arriving at Cali via Santo Domingo de los Colorados and Quito. The journey, including transfers, takes approximately 22 h 10 min.

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The distance between Guayaquil and Cali is 732 km. The road distance is 1210.4 km.

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The best way to get from Guayaquil to Cali without a car is to bus which takes 22 h 10 min and costs $70 - $95.

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It takes approximately 2 h 29 min to get from Guayaquil to Cali, including transfers.

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Guayaquil to Cali bus services, operated by Cooperativa de Transportes Zaracay, depart from Guayaquil station.

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The best way to get from Guayaquil to Cali is to fly which takes 2 h 29 min and costs $200 - $470. Alternatively, you can bus, which costs $70 - $95 and takes 22 h 10 min.

Mode details

The quickest flight from Guayaquil Airport to Cali Airport is the direct flight which takes 1 h 30 min.

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Guayaquil to Cali bus services, operated by Omega, arrive at Cali station.

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Map of how to get from Guayaquil to Cali.
Launch map view
  • Distance: 457.3 miles
  • Duration: 2 h 29 min

What companies run services between Guayaquil, Ecuador and Cali, Colombia?

Avianca - Aerovías del Continente Americano S.A. flies from Guayaquil to Cali once daily. Alternatively, Expreso Internacional Ormeño operates a bus from Guayaquil to Cali 3 times a week. Tickets cost $50 - $70 and the journey takes 22 h.

Airlines
Avianca - Aerovías del Continente Americano S.A.
Website
avianca.com
Flights from Guayaquil to Cali
Ave. Duration
1 h 30 min
When
Every day
Estimated price
$370 - $900
Bus operators
Cooperativa de Transportes Zaracay
Phone
(+593)-0236547894
Website
transporteszaracay.com.ec
Bus from Guayaquil to Santo Domingo de los Colorados
Ave. Duration
5 h
Frequency
Hourly
Estimated price
$7
Schedules at
transporteszaracay.com.ec
Book at
andestransit.com
Panamericana Internacional
Phone
+593 (2) 2557133 / 2557134
Email
info@panamericana.ec
Website
panamericana.ec
Bus from Santo Domingo de los Colorados to Quito - Terminal Quitumbe
Ave. Duration
1 h 45 min
Frequency
Every 10 minutes
Estimated price
$6 - $10
Schedules at
panamericana.ec
Tiseca
Phone
+58 276 7713091
Website
tiseca.com.ve
Bus from Quito to Cali
Ave. Duration
16 h
Frequency
Hourly
Schedules at
tiseca.com.ve
Rutas de America
Phone
+51 1 992651360
Email
rutasenbus@hotmail.com
Website
rutasenbus.com
Bus from Quito to Cali
Ave. Duration
14 h
Frequency
Twice daily
Schedules at
rutasenbus.com
Alianza Internacional del Sur
Website
facebook.com
Bus from Quito to Cali
Ave. Duration
14 h
Frequency
Once daily
Schedules at
venezuelatravelinternational.com
Book at
venezuelatravelinternational.com
Cooperativa de Transportes Aerotaxi
Phone
593 99 195 2081
Email
transportesaerotaxi@yahoo.com
Website
coop_transporte_aerotaxi.amawebs.com
Bus from Guayaquil to Quito Terminal Quitumbe
Ave. Duration
8 h 5 min
Frequency
Every 2 hours
Estimated price
$14
Schedules at
coop_transporte_aerotaxi.amawebs.com
Book at
andestransit.com

Want to know more about travelling around the world?

Rome2rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including How to plan an amazing trip around Scandinavia, Train travel in France: A guide to SNCF and Getting to Rome from the airport - to help you get the most out of your next trip.

More Questions & Answers

Yes, the driving distance between Guayaquil to Cali is 1210 km. It takes approximately 19 h 51 min to drive from Guayaquil to Cali.

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Avianca - Aerovías del Continente Americano S.A. offers flights from Guayaquil Airport to Cali Airport.

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There are 530+ hotels available in Cali. Prices start at $17 USD per night.

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The best way to get from Guayaquil to Guayaquil Airport is to taxi which takes 9 min and costs $18 - $23.

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