There are 3 ways to get from Guatemala City to Santa Ana by bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  3 h 30 min

  1. Take the bus from Guatemala City Holiday Inn to Santa Ana

$29

2 alternative options

Drive  •  2 h 36 min

  1. Drive from Guatemala City to Santa Ana 110.1 miles

$12 - $19

Fly, bus  •  5 h 3 min

  1. Fly from Guatemala City (GUA) to San Salvador (SAL) GUA - SAL
  2. Take the bus from Zacatecoluca to San Salvador
  3. Take the bus from Terminal de Buses de Occidente, Calle El Estadio No 2, Colonia El Rosal, Colonia 3 de Mayo, Reparto Caribe, San Salvador, Municipio de San Salvador, Departamento de San Salvador, El Salvador to Santa Ana

$86 - $187

Questions & Answers

The cheapest way to get from Guatemala City to Santa Ana is to drive which costs $12 - $19 and takes 2 h 36 min.

More details

The quickest way to get from Guatemala City to Santa Ana is to drive which costs $12 - $19 and takes 2 h 36 min.

More details

The distance between Guatemala City and Santa Ana is 125 km. The road distance is 176.2 km.

Get driving directions

The bus from Guatemala City Holiday Inn to Santa Ana takes 3 h 30 min including transfers and departs four times a day.

More details

Yes, there is a direct bus departing from Guatemala City Holiday Inn and arriving at Santa Ana. Services depart four times a day, and operate every day. The journey takes approximately 3 h 30 min.

More details

What companies run services between Guatemala City, Guatemala and Santa Ana, El Salvador?

Pullmantur operates a bus from Guatemala City to Santa Ana 4 times a day. Tickets cost $29 and the journey takes 3 h 30 min.

Airlines
Avianca - Aerovías del Continente Americano S.A.
Website
avianca.com
Flights from Guatemala City to San Salvador
Ave. Duration
53 min
When
Every day
Estimated price
$120 - $340
Iberia
Website
iberia.com
Flights from Guatemala City to San Salvador
Ave. Duration
55 min
When
Tuesday, Thursday, Saturday and Sunday
Estimated price
$16 - $100
Skytrans
Website
skytrans.com.au
Flights from Guatemala City to San Salvador
Ave. Duration
1 h 1 min
When
Monday, Wednesday and Friday
Estimated price
$26 - $250
Bus operators
bus
Bus from Zacatecoluca to San Salvador
Ave. Duration
27 min
Frequency
Every 30 minutes
Estimated price
$2
Horario De Buses
Website
thebusschedule.com
Bus from Terminal de Buses de Occidente, Calle El Estadio No 2, Colonia El Rosal, Colonia 3 de Mayo, Reparto Caribe, San Salvador, Municipio de San Salvador, Departamento de San Salvador, El Salvador to Santa Ana
Ave. Duration
1 h 22 min
Frequency
Every 10 minutes
Schedules at
thebusschedule.com
bus
Bus from San Salvador to Santa Ana
Ave. Duration
1 h 15 min
Frequency
Every 30 minutes
Estimated price
$2

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