There are 2 ways to get from Guatemala City to Santa Ana by bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  3 h 30 min

  1. Take the bus from Guatemala City Holiday Inn to Santa Ana

$28

1 alternative option

Drive  •  2 h 36 min

  1. Drive from Guatemala City to Santa Ana 110.1 miles

$12 - $19

Questions & Answers

Yes, there is a direct bus departing from Guatemala City Holiday Inn and arriving at Santa Ana. Services depart four times a day, and operate every day. The journey takes approximately 3 h 30 min.

More details

The distance between Guatemala City and Santa Ana is 125 km. The road distance is 176.2 km.

Get driving directions

The best way to get from Guatemala City to Santa Ana without a car is to bus which takes 3 h 30 min and costs .

More details

The bus from Guatemala City Holiday Inn to Santa Ana takes 3 h 30 min including transfers and departs four times a day.

More details

Guatemala City to Santa Ana bus services, operated by Pullmantur, depart from Guatemala City Holiday Inn station.

More details

Guatemala City to Santa Ana bus services, operated by Pullmantur, arrive at Santa Ana station.

More details

Yes, the driving distance between Guatemala City to Santa Ana is 176 km. It takes approximately 2 h 36 min to drive from Guatemala City to Santa Ana.

Get driving directions

There are 36+ hotels available in Santa Ana. Prices start at $12 USD per night.

More details

Map of how to get from Guatemala City to Santa Ana.
Launch map view
  • Distance: 78.4 miles
  • Duration: 3 h 30 min

What companies run services between Guatemala City, Guatemala and Santa Ana, El Salvador?

Pullmantur operates a bus from Guatemala City to Santa Ana 4 times a day. Tickets cost $28 and the journey takes 3 h 30 min.

Want to know more about travelling around the world?

Rome2rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including Train travel in Spain: A guide to Renfe, Getting around the Cyclades and 5 delightfully under-the-radar French towns you need to visit - to help you get the most out of your next trip.